MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway

Maresin 1 attenuates the inflammatory response and mitochondrial damage in mice with cerebral ischemia/reperfusion in a SIRT1-dependent manner

(2019) Wenjing Xian et al.   BRAIN RESEARCH

Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome

(2019) Brooke A. Napier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tanshinone IIA protects against lipopolysaccharide-induced lung injury through targeting Sirt1

(2019) Minxue Quan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Sonchus oleraceus Linn protects against LPS-induced sepsis and inhibits inflammatory responses in RAW264.7 cells

(2019) Lei Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Heme oxygenase-1 induction by rosiglitazone via PKCα/AMPKα/p38 MAPKα/SIRT1/PPARγ pathway suppresses lipopolysaccharide-mediated pulmonary inflammation

(2018) Rou-Ling Cho et al.   BIOCHEMICAL PHARMACOLOGY

LncRNA H19 functions as an Aquaporin 1 competitive endogenous RNA to regulate microRNA-874 expression in LPS sepsis

(2018) Yu Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

Resolvin D1 Promotes SIRT1 Expression to Counteract the Activation of STAT3 and NF-κB in Mice with Septic-Associated Lung Injury

(2018) Yuzhen Zhuo et al.   INFLAMMATION

Maresin 1 attenuates mitochondrial dysfunction through the ALX/cAMP/ROS pathway in the cecal ligation and puncture mouse model and sepsis patients

(2018) Jiaqi Gu et al.   LABORATORY INVESTIGATION

Review: the Role and Mechanisms of Macrophage Autophagy in Sepsis

(2018) Peng Qiu et al.   INFLAMMATION

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration

(2018) Martin Schlegel et al.   JOURNAL OF CLINICAL INVESTIGATION

Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNFα and JNK/NF-κB pathways in HK-2 cells

(2017) Wei Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin inhibits angiotensin II-induced inflammation and proliferation of rat vascular smooth muscle cells by elevating PPAR-γ activity and reducing oxidative stress

(2017) Hai-Yu Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis

(2017) Shiyan Peng et al.   Oxidative Medicine and Cellular Longevity

Magnolol attenuates the inflammation and apoptosis through the activation of SIRT1 in experimental stroke rats

(2017) Dong-Quan Kou et al.   Pharmacological Reports

miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model

(2017) Dagmar Pfeiffer et al.   PLoS One

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response

(2017) Yung-Li Hung et al.   Scientific Reports

The pro-resolving lipid mediator Maresin 1 protects against cerebral ischemia/reperfusion injury by attenuating the pro-inflammatory response

(2016) Wenjing Xian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related signaling

(2016) Wenhui Zhong et al.   BIOMEDICINE & PHARMACOTHERAPY

Resolvin D1, resolvin D2 and maresin 1 activate the GSK3β anti-inflammatory axis in TLR4-engaged human monocytes

(2016) Zhen Gu et al.   Innate Immunity

MicroRNA-205-5b inhibits HMGB1 expression in LPS-induced sepsis

(2016) WENHAI ZHOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons

(2016) Johanna Mäkelä et al.   NEUROPHARMACOLOGY

Adiponectin Protects against Glutamate-Induced Excitotoxicity via Activating SIRT1-Dependent PGC-1αExpression in HT22 Hippocampal Neurons

(2016) Liang Yue et al.   Oxidative Medicine and Cellular Longevity

Sirtuins Link Inflammation and Metabolism

(2016) Vidula T. Vachharajani et al.   Journal of Immunology Research

Sirt1 restrains lung inflammasome activation in a murine model of sepsis

(2015) Rong Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sirtuin regulation in aging and injury

(2015) Ninu Poulose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

(2015) Jae-Min Yuk et al.   IMMUNITY

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

(2014) Limei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Resveratrol and SIRT1 on PGC-1α Activity and Mitochondrial Biogenesis: A Reevaluation

(2013) Kazuhiko Higashida et al.   PLOS BIOLOGY

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS