Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery

DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen

(2019) Grace Cole et al.   Acta Biomaterialia

Delivery of RALA/siFKBPL nanoparticles via electrospun bilayer nanofibres: An innovative angiogenic therapy for wound repair

(2019) Eoghan J. Mulholland et al.   JOURNAL OF CONTROLLED RELEASE

DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system

(2018) Grace Cole et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles

(2017) Ahlam A. Ali et al.   Nanomedicine-Nanotechnology Biology and Medicine

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

(2017) Vimal K. Udhayakumar et al.   Advanced Healthcare Materials

Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment

(2017) Cian M. McCrudden et al.   Molecular Therapy-Nucleic Acids

Nonhemolytic Cell-Penetrating Peptides: Site Specific Introduction of Glutamine and Lysine Residues into the α-Helical Peptide Causes Deletion of Its Direct Membrane Disrupting Ability but Retention of Its Cell Penetrating Ability

(2016) Seoyeon Kim et al.   BIOMACROMOLECULES

Potentiating the Anticancer Properties of Bisphosphonates by Nanocomplexation with the Cationic Amphipathic Peptide, RALA

(2016) Ashley S. Massey et al.   MOLECULAR PHARMACEUTICS

RALA-mediated delivery of FKBPL nucleic acid therapeutics

(2015) Rachel Bennett et al.   Nanomedicine

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

The Uptake of Arginine-Rich Cell-Penetrating Peptides: Putting the Puzzle Together

(2014) Roland Brock   BIOCONJUGATE CHEMISTRY

Contrasting effects of cysteine modification on the transfection efficiency of amphipathic peptides

(2014) Rajpal Sharma et al.   BIOMATERIALS

Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

(2014) Helen O. McCarthy et al.   JOURNAL OF CONTROLLED RELEASE

Linear Short Histidine and Cysteine Modified Arginine Peptides Constitute a Potential Class of DNA Delivery Agents

(2014) Anita Mann et al.   MOLECULAR PHARMACEUTICS

Cell-penetrating peptides: 20 years later, where do we stand?

(2013) Chérine Bechara et al.   FEBS LETTERS

Endocytosis of Gene Delivery Vectors: From Clathrin-dependent to Lipid Raft-mediated Endocytosis

(2013) Ayman El-Sayed et al.   MOLECULAR THERAPY

Effects of Tryptophan Content and Backbone Spacing on the Uptake Efficiency of Cell-Penetrating Peptides

(2012) Hanna A. Rydberg et al.   BIOCHEMISTRY

Novel gene transfer vectors based on artificial recombinant multi-functional oligopeptides

(2012) Kai Han et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cell entry of cell penetrating peptides: tales of tails wagging dogs

(2012) Arwyn T. Jones et al.   JOURNAL OF CONTROLLED RELEASE

Biodistribution Studies of Nanoparticles Using Fluorescence Imaging: A Qualitative or Quantitative Method?

(2012) Yang Liu et al.   PHARMACEUTICAL RESEARCH

Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

(2011) Ikuhiko Nakase et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Novel, Bio-Reducible Gene Vector Containing Arginine and Histidine Enhances Gene Transfection and Expression of Plasmid DNA

(2011) Ko Tanaka et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Differences in DNA Condensation and Release by Lysine and Arginine Homopeptides Govern Their DNA Delivery Efficiencies

(2011) Anita Mann et al.   MOLECULAR PHARMACEUTICS

Cell-penetrating peptide exploited syndecans

(2010) Tamás Letoha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

PEP and CADY-mediated delivery of fluorescent peptides and proteins into living cells

(2010) Laetitia Kurzawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Different membrane behaviour and cellular uptake of three basic arginine-rich peptides

(2010) Astrid Walrant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

(2009) Ayman El-Sayed et al.   AAPS Journal

Delivery of Nucleic Acids via Disulfide-Based Carrier Systems

(2009) Sonja Bauhuber et al.   ADVANCED MATERIALS

Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate

(2009) Peter Guterstam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

(2009) Frederic Heitz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fractal analysis and ionic dependence of endocytotic membrane activity of human breast cancer cells

(2009) Monika Krasowska et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Arginine-rich cell-penetrating peptides

(2009) Nathan Schmidt et al.   FEBS LETTERS

An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection

(2008) Seong Loong Lo et al.   BIOMATERIALS

Peptides in DNA delivery: current insights and future directions

(2008) A MANN et al.   DRUG DISCOVERY TODAY

A New Potent Secondary Amphipathic Cell–penetrating Peptide for siRNA Delivery Into Mammalian Cells

(2008) Laurence Crombez et al.   MOLECULAR THERAPY

Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides

(2007) Ikuhiko Nakase et al.   ADVANCED DRUG DELIVERY REVIEWS