Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells

PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells

(2020) Mingcan Yu et al.   Nature Communications

Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota

(2020) Jau-Yi Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin 17A: a Janus-faced regulator of osteoporosis

(2020) J. M. Scheffler et al.   Scientific Reports

The gut-bone axis: how bacterial metabolites bridge the distance

(2019) Mario M. Zaiss et al.   JOURNAL OF CLINICAL INVESTIGATION

Host defense against oral microbiota by bone-damaging T cells

(2018) Masayuki Tsukasaki et al.   Nature Communications

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney

(2016) Christian F. Krebs et al.   IMMUNITY

Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

(2016) Jau-Yi Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

(2016) Tze Guan Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic skin inflammation leads to bone loss by IL-17–mediated inhibition of Wnt signaling in osteoblasts

(2016) Özge Uluçkan et al.   Science Translational Medicine

IL-17-producing γδ T cells enhance bone regeneration

(2016) Takehito Ono et al.   Nature Communications

Bone Loss in Surgically Ovariectomized Premenopausal Women Is Associated With T Lymphocyte Activation and Thymic Hypertrophy

(2016) Saira Adeel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice

(2015) Jau-Yi Li et al.   Cell Metabolism

T Cell-Expressed CD40L Potentiates the Bone Anabolic Activity of Intermittent PTH Treatment

(2015) Jerid W Robinson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency

(2015) Francesco Grassi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Induction of Th17 cells by segmented filamentous bacteria in the murine intestine

(2015) Adam M. Farkas et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Exit Strategies: S1P Signaling and T Cell Migration

(2015) Audrey Baeyens et al.   TRENDS IN IMMUNOLOGY

IL-17 inhibits osteoblast differentiation and bone regeneration in rat

(2014) Yong-Gun Kim et al.   ARCHIVES OF ORAL BIOLOGY

Changes of serum cytokines-related Th1/Th2/Th17 concentration in patients with postmenopausal osteoporosis

(2014) Jing Zhang et al.   GYNECOLOGICAL ENDOCRINOLOGY

Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation

(2014) Yoshiyuki Goto et al.   IMMUNITY

Enhanced Immunoprotective Effects by Anti-IL-17 Antibody Translates to Improved Skeletal Parameters Under Estrogen Deficiency Compared With Anti-RANKL and Anti-TNF-α Antibodies

(2014) Abdul M Tyagi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut

(2014) A. M. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER–ERK–mTOR pathway

(2013) Yue-Hua Yang et al.   APOPTOSIS

Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B

(2013) J.-Y. Li et al.   BLOOD

The Th17 family: flexibility follows function

(2013) Rajatava Basu et al.   IMMUNOLOGICAL REVIEWS

The Sclerostin-Independent Bone Anabolic Activity of Intermittent PTH Treatment Is Mediated by T-Cell-Produced Wnt10b

(2013) Jau-Yi Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of T cells in ovariectomy induced bone loss-revisited

(2012) Roberto Pacifici   JOURNAL OF BONE AND MINERAL RESEARCH

IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner

(2012) Carl J. DeSelm et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis

(2012) Abdul M. Tyagi et al.   PLoS One

Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors

(2012) Iannis E Adamopoulos et al.   ARTHRITIS RESEARCH & THERAPY

Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease

(2012) Sunao Sugita et al.   ARTHRITIS RESEARCH & THERAPY

T helper cell populations: As flexible as the skin?

(2011) Ari Waisman   EUROPEAN JOURNAL OF IMMUNOLOGY

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

CXCL10 expressing hematopoietic-derived cells are requisite in defense against HSV-1 infection in the nervous system of CXCL10 deficient mice

(2011) Todd R. Wuest et al.   JOURNAL OF NEUROIMMUNOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy

(2011) Der-Yuan Chen et al.   ARTHRITIS RESEARCH & THERAPY

Bone, Inflammation, and Inflammatory Bowel Disease

(2011) Manasi Agrawal et al.   Current Osteoporosis Reports

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

(2010) Jerold Chun et al.   CLINICAL NEUROPHARMACOLOGY

Increased PTHrP and Decreased Estrogens Alter Bone Turnover but Do Not Reproduce the Full Effects of Lactation on the Skeleton

(2010) Laleh Ardeshirpour et al.   ENDOCRINOLOGY

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

TNFα-exposed Bone Marrow-derived Mesenchymal Stem Cells Promote Locomotion of MDA-MB-231 Breast Cancer Cells through Transcriptional Activation of CXCR3 Ligand Chemokines

(2010) Soon Young Shin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

(2010) Michio Tomura et al.   JOURNAL OF CLINICAL INVESTIGATION

CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis

(2010) J. E. Turner et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand

(2010) J.-Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation and Function of Proinflammatory TH17 Cells

(2009) Gustavo J. Martinez et al.   Annals of the New York Academy of Sciences

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis

(2008) Patrizia D'Amelio et al.   BONE

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

(2008) Susan A Krum et al.   EMBO JOURNAL

Monitoring cellular movement in vivo with photoconvertible fluorescence protein "Kaede" transgenic mice

(2008) M. Tomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The highway code of T cell trafficking

(2007) FM Marelli-Berg et al.   JOURNAL OF PATHOLOGY