FGF19 protects skeletal muscle against obesity‐induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT‐1/PGC‐α pathway

Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration

(2020) Zhen Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis

(2020) Qiu-Nan Chen et al.   EXPERIMENTAL CELL RESEARCH

Linking epidemiology and molecular mechanisms in sarcopenic obesity in populations

(2020) Issam El Bizri et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

New insights into the cellular activities of Fndc5/Irisin and its signaling pathways

(2020) Farzaneh Rabiee et al.   Cell and Bioscience

Fibroblast growth factor 19 alleviates palmitic acid-induced mitochondrial dysfunction and oxidative stress via the AMPK/PGC-1α pathway in skeletal muscle

(2020) Ai Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of Melatonin on Lipid Metabolism and Circulating Irisin in Sprague-Dawley Rats with Diet-Induced Obesity

(2020) Yu-Tang Tung et al.   MOLECULES

Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux

(2020) Zhen Fan et al.   LIFE SCIENCES

Obesity: global epidemiology and pathogenesis

(2019) Matthias Blüher   Nature Reviews Endocrinology

Thirty sweet years of GLUT4

(2019) Amira Klip et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega-3 Fatty Acids-Enriched Fish Oil Activates AMPK/PGC-1α Signaling and Prevents Obesity-Related Skeletal Muscle Wasting

(2019) Shing-Hwa Liu et al.   Marine Drugs

Sarcopenic Obesity: Epidemiologic Evidence, Pathophysiology, and Therapeutic Perspectives

(2019) Chrysi Koliaki et al.   Current Obesity Reports

Metabolic Health—The Role of Adipo-Myokines

(2019) Christine Graf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Brown adipose tissue and lipid metabolism

(2018) Joerg Heeren et al.   CURRENT OPINION IN LIPIDOLOGY

AMPK in skeletal muscle function and metabolism

(2018) Rasmus Kjøbsted et al.   FASEB JOURNAL

An Overview of FGF19 and FGF21: The Therapeutic Role in the Treatment of the Metabolic Disorders and Obesity

(2018) Nasim Babaknejad et al.   HORMONE AND METABOLIC RESEARCH

Sarcopenic obesity

(2018) Stergios A. Polyzos et al.   Hormones-International Journal of Endocrinology and Metabolism

Fibroblast Growth Factor 15/19 – From Basic Functions to Therapeutic Perspectives

(2018) Emmanuel Somm et al.   ENDOCRINE REVIEWS

Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

(2018) John A. Batsis et al.   Nature Reviews Endocrinology

The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration

(2018) David Thomson   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PGC-1α as a Pivotal Factor in Lipid and Metabolic Regulation

(2018) Ching-Feng Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway

(2017) Zhi-Yin Liao et al.   EXPERIMENTAL GERONTOLOGY

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

(2017) Gloria Alvarez-Sola et al.   GUT

Skeletal muscle inflammation and insulin resistance in obesity

(2017) Huaizhu Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Apigenin Ameliorates the Obesity-Induced Skeletal Muscle Atrophy by Attenuating Mitochondrial Dysfunction in the Muscle of Obese Mice

(2017) Won Hee Choi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice

(2017) Bérengère Benoit et al.   NATURE MEDICINE

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

(2017) Musarrat Maisha Reza et al.   Nature Communications

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

(2016) Rasmus Kjøbsted et al.   DIABETES

SIRT1 and insulin resistance

(2016) Yue Cao et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

Lipid modulation of skeletal muscle mass and function

(2016) Christopher Lipina et al.   Journal of Cachexia Sarcopenia and Muscle

The physiological roles of Sirt1 in skeletal muscle

(2016) Patricia S. Pardo et al.   Aging-US

Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism

(2016) Junaith S. Mohamed et al.   Aging-US

The impact of obesity on skeletal muscle strength and structure through adolescence to old age

(2015) D. J. Tomlinson et al.   BIOGERONTOLOGY

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease

(2015) Daniel Jahn et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Irisin, a unique non-inflammatory myokine in stimulating skeletal muscle metabolism

(2015) Roger A. Vaughan et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading

(2015) Jessica Cannavino et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Skeletal Muscle: A Brief Review of Structure and Function

(2014) Walter R. Frontera et al.   CALCIFIED TISSUE INTERNATIONAL

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm

(2012) Marion Pauly et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of PGC-1α signaling in skeletal muscle health and disease

(2012) Chounghun Kang et al.   Annals of the New York Academy of Sciences

SIRT1 signaling as potential modulator of skeletal muscle diseases

(2012) Joanne Tonkin et al.   CURRENT OPINION IN PHARMACOLOGY

Fibroblast Growth Factor-19 Action in the Brain Reduces Food Intake and Body Weight and Improves Glucose Tolerance in Male Rats

(2012) Karen K. Ryan et al.   ENDOCRINOLOGY

Dual actions of fibroblast growth factor 19 on lipid metabolism

(2012) Xinle Wu et al.   JOURNAL OF LIPID RESEARCH

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deacetylation of PGC-1α by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis

(2011) Brendon J. Gurd   Applied Physiology Nutrition and Metabolism

Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat

(2011) Iman Momken et al.   FASEB JOURNAL

Angiotensin II Upregulates Protein Phosphatase 2Cα and Inhibits AMP-Activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting

(2011) A. Michael Tabony et al.   HYPERTENSION

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model

(2010) Balindiwe Sishi et al.   EXPERIMENTAL PHYSIOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA