Maternal Low-Grade Chronic Inflammation and Intrauterine Programming of Health and Disease

Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging

(2020) Hiroshi Tamura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In utero Exposure to Maternal Chronic Inflammation Transfers a Pro-Inflammatory Profile to Generation F2 via Sex-Specific Mechanisms

(2020) Rozanne Charlene McChary Adams et al.   Frontiers in Immunology

Placental function in maternal obesity

(2020) Amy C. Kelly et al.   CLINICAL SCIENCE

Maternal high-fat diet induces long-term obesity with sex-dependent metabolic programming of adipocyte differentiation, hypertrophy and dysfunction in the offspring

(2020) Thorsten Litzenburger et al.   CLINICAL SCIENCE

Maternal Obesity and the Uterine Immune Cell Landscape: The Shaping Role of Inflammation

(2020) Lauren E. St-Germain et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolomic alternations of follicular fluid of obese women undergoing in-vitro fertilization treatment

(2020) Jingyan Song et al.   Scientific Reports

Perinatal exposure to maternal obesity: Lasting cardiometabolic impact on offspring

(2020) Sezen Kislal et al.   PRENATAL DIAGNOSIS

Maternal Obesity Influences Placental Nutrient Transport, Inflammatory Status, and Morphology in Human Term Placenta

(2020) Perrine Nogues et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?

(2020) Vidit V Satokar et al.   NUTRITION REVIEWS

Placental Adaptive Changes to Protect Function and Decrease Oxidative Damage in Metabolically Healthy Maternal Obesity

(2020) Celeste Santos-Rosendo et al.   Antioxidants

The role of obesity and gestational diabetes on placental size and fetal oxygenation

(2020) Chiara Bianchi et al.   PLACENTA

Pre-pregnancy BMI is associated with offspring body composition in adulthood before adiposity-related disorders: a retrospective cohort

(2020) Ilana Eshriqui et al.   PUBLIC HEALTH NUTRITION

Behavioral Feeding Circuit: Dietary Fat-Induced Effects of Inflammatory Mediators in the Hypothalamus

(2020) Kinning Poon   Frontiers in Endocrinology

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

(2019) Ellis Voerman et al.   PLOS MEDICINE

Sex modifies placental gene expression in response to metabolic and inflammatory stress

(2019) Theresa L. Barke et al.   PLACENTA

Periconceptional environment and the developmental origins of disease

(2019) Miguel A Velazquez et al.   JOURNAL OF ENDOCRINOLOGY

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

(2019) Chantel L. Martin et al.   Epigenetics

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American, and Australian cohorts

(2019) S Santos et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Obesity Induces Ovarian Inflammation and Reduces Oocyte Quality

(2019) Alexandria P Snider et al.   REPRODUCTION

Prepregnancy Obesity, Maternal Dietary Intake, and Oxidative Stress Biomarkers in the Fetomaternal Unit

(2019) Ana Karen Ballesteros-Guzmán et al.   Biomed Research International

Intrauterine programming of obesity and type 2 diabetes

(2019) Denise S. Fernandez-Twinn et al.   DIABETOLOGIA

Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny

(2019) R. C. M. Adams et al.   MEDIATORS OF INFLAMMATION

Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse†

(2018) Tami J Stuart et al.   BIOLOGY OF REPRODUCTION

Maternal obesity alters uterine NK activity through a functional KIR2DL1/S1 imbalance

(2018) Barbara Castellana et al.   IMMUNOLOGY AND CELL BIOLOGY

Embryotoxic cytokines—Potential roles in embryo loss and fetal programming

(2018) Sarah A. Robertson et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health

(2018) Judith Stephenson et al.   LANCET

Perinatal Origins of Adult Disease

(2018) Umberto Simeoni et al.   Neonatology

Association of Maternal Prepregnancy Body Mass Index With Placental Histopathological Characteristics in Uncomplicated Term Pregnancies

(2018) Laura Brouwers et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Preliminary metabolomics analysis of placenta in maternal obesity

(2018) Claudia Fattuoni et al.   PLACENTA

Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial

(2018) Yangying Xu et al.   Reproductive Biology and Endocrinology

Inflammatory and Oxidative Responses in Pregnancies With Obesity and Periodontal Disease

(2018) Marta Zambon et al.   Reproductive Sciences

Inflammatory markers in human follicular fluid correlate with lipid levels and Body Mass Index

(2018) Macarena B. Gonzalez et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Impact of Obesity and Hyperglycemia on Placental Mitochondria

(2018) Chiara Mandò et al.   Oxidative Medicine and Cellular Longevity

Association Between Prepregnancy Body Mass Index and Severe Maternal Morbidity

(2017) Sarka Lisonkova et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective

(2017) Meghan L. Ruebel et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Programmed hyperphagia in offspring of obese dams: Altered expression of hypothalamic nutrient sensors, neurogenic factors and epigenetic modulators

(2016) Mina Desai et al.   APPETITE

Adiponectin Inhibits Nutrient Transporters and Promotes Apoptosis in Human Villous Cytotrophoblasts: Involvement in the Control of Fetal Growth1

(2016) Fabien Duval et al.   BIOLOGY OF REPRODUCTION

Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet

(2016) Michael D. Thompson et al.   GENE EXPRESSION

Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy

(2016) Julie S. Rhee et al.   HUMAN REPRODUCTION

Sex specific adaptations in placental biometry of overweight and obese women

(2016) Chiara Mandò et al.   PLACENTA

Maternal obesity and sex-specific differences in placental pathology

(2016) Sandra M. Leon-Garcia et al.   PLACENTA

The effect of maternal Inflammation on foetal programming of metabolic disease

(2015) C. Ingvorsen et al.   Acta Physiologica

Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project

(2015) Kristen E. Boyle et al.   DIABETES

Reproductive outcomes in oocyte donation cycles are associated with donor BMI

(2015) E.R. Cardozo et al.   HUMAN REPRODUCTION

Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity

(2015) S Muralimanoharan et al.   INTERNATIONAL JOURNAL OF OBESITY

Eicosapentaenoic Acid Reduces Adipocyte Hypertrophy and Inflammation in Diet-Induced Obese Mice in an Adiposity-Independent Manner

(2015) Monique J LeMieux et al.   JOURNAL OF NUTRITION

Maternal obesity and high-fat diet program offspring metabolic syndrome

(2014) Mina Desai et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Increasing Maternal Body Mass Index Is Associated with Systemic Inflammation in the Mother and the Activation of Distinct Placental Inflammatory Pathways1

(2014) Irving L.M.H. Aye et al.   BIOLOGY OF REPRODUCTION

Pregnancy and Infants’ Outcome: Nutritional and Metabolic Implications

(2014) C. Berti et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Longitudinal changes in serum proinflammatory markers across pregnancy and postpartum: Effects of maternal body mass index

(2014) Lisa M. Christian et al.   CYTOKINE

Effects of pregnancy on obesity-induced inflammation in a mouse model of fetal programming

(2014) C Ingvorsen et al.   INTERNATIONAL JOURNAL OF OBESITY

Maternal obesity is associated with a lipotoxic placental environment

(2014) J. Saben et al.   PLACENTA

Maternal Obesity, Inflammation, and Developmental Programming

(2014) Stephanie A. Segovia et al.   Biomed Research International

Maternal high-fat diets cause insulin resistance through inflammatory changes in fetal adipose tissue

(2013) N. Murabayashi et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

How Early Should Obesity Prevention Start?

(2013) Matthew W. Gillman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pro-Inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans

(2013) Lisbeth N. Fink et al.   Obesity

LPS Exposure Increases Maternal Corticosterone Levels, Causes Placental Injury and Increases IL-1Β Levels in Adult Rat Offspring: Relevance to Autism

(2013) Thiago B. Kirsten et al.   PLoS One

Body mass index and height over three generations: evidence from the Lifeways cross-generational cohort study

(2012) Celine M Murrin et al.   BMC PUBLIC HEALTH

Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response

(2012) Devon B. Oskvig et al.   BRAIN BEHAVIOR AND IMMUNITY

Metabolic Syndrome in Adolescence

(2012) Stamatis P. Efstathiou et al.   CIRCULATION

Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes

(2012) Xing Yang et al.   FERTILITY AND STERILITY

Intrahepatic Fat Is Increased in the Neonatal Offspring of Obese Women with Gestational Diabetes

(2012) David E. Brumbaugh et al.   JOURNAL OF PEDIATRICS

Cardiovascular Risk Factors in Children and Young Adults Born to Preeclamptic Pregnancies: A Systematic Review

(2012) E. F. Davis et al.   PEDIATRICS

Placental weight and efficiency in relation to maternal body mass index and the risk of pregnancy complications in women delivering singleton babies

(2012) J.M. Wallace et al.   PLACENTA

Placental fatty acid transport in maternal obesity

(2012) I. Cetin et al.   Journal of Developmental Origins of Health and Disease

Mechanisms of early life programming: current knowledge and future directions

(2011) Jane L Tarry-Adkins et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Survival effects of prenatal famine exposure

(2011) Annet FM van Abeelen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Inflammation and pregnancy: the role of the immune system at the implantation site

(2011) Gil Mor et al.   Annals of the New York Academy of Sciences

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Association of Maternal Diabetes Mellitus in Pregnancy With Offspring Adiposity Into Early Adulthood

(2011) Debbie A. Lawlor et al.   CIRCULATION

Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models

(2011) M. Li et al.   Experimental Diabetes Research

Placental structure and inflammation in pregnancies associated with obesity

(2011) K.A. Roberts et al.   PLACENTA

Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus

(2011) J. Wienecke et al.   PLACENTA

Prenatal origin of obesity and their complications: Gestational diabetes, maternal overweight and the paradoxical effects of fetal growth restriction and macrosomia

(2011) Asher Ornoy   REPRODUCTIVE TOXICOLOGY

Maternal obesity associated with inflammation in their children

(2011) Karen L. Leibowitz et al.   World Journal of Pediatrics

Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring

(2010) Bianca M. Gregorio et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Full-Length Adiponectin Attenuates Insulin Signaling and Inhibits Insulin-Stimulated Amino Acid Transport in Human Primary Trophoblast Cells

(2010) H. N. Jones et al.   DIABETES

Impact of Maternal Periconceptional Overnutrition on Fat Mass and Expression of Adipogenic and Lipogenic Genes in Visceral and Subcutaneous Fat Depots in the Postnatal Lamb

(2010) L. Rattanatray et al.   ENDOCRINOLOGY

Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring1

(2010) N. M. Long et al.   JOURNAL OF ANIMAL SCIENCE

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ

(2010) Eve Draper et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of Pre-Pregnancy Body Mass Index and Gestational Weight Gain on Infant Anthropometric Outcomes

(2010) Andrea L. Deierlein et al.   JOURNAL OF PEDIATRICS

Pregravid Obesity Associates With Increased Maternal Endotoxemia and Metabolic Inflammation

(2010) Subhabrata Basu et al.   Obesity

Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta

(2010) M.J. Zhu et al.   PLACENTA

Obesity, pregnancy, inflammation, and vascular function

(2010) F C Denison et al.   REPRODUCTION

IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2

(2009) H. N. Jones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Leptin Stimulates Protein Synthesis-Activating Translation Machinery in Human Trophoblastic Cells1

(2009) Antonio Pérez-Pérez et al.   BIOLOGY OF REPRODUCTION

Maternal Obesity, Inflammation, and Fetal Skeletal Muscle Development1

(2009) Min Du et al.   BIOLOGY OF REPRODUCTION

Up-Regulation of Toll-Like Receptor 4/Nuclear Factor-κB Signaling Is Associated with Enhanced Adipogenesis and Insulin Resistance in Fetal Skeletal Muscle of Obese Sheep at Late Gestation

(2009) Xu Yan et al.   ENDOCRINOLOGY

Decidual leucocyte populations in early to late gestation normal human pregnancy

(2009) P.J. Williams et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

(2009) E. Maury et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Association of Parental Obesity With Concentrations of Select Systemic Biomarkers in Nonobese Offspring: The Framingham Heart Study

(2008) W. Lieb et al.   DIABETES

Differential inflammatory status in rats susceptible or resistant to diet-induced obesity: effects of EPA ethyl ester treatment

(2008) Nerea Pérez-Echarri et al.   EUROPEAN JOURNAL OF NUTRITION

Uterine DCs are crucial for decidua formation during embryo implantation in mice

(2008) Vicki Plaks et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

(2008) J.C. Challier et al.   PLACENTA

Predictive adaptive responses in perspective

(2008) Peter D. Gluckman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION