- Home
- Publications
- Publication Search
- Publication Details
Title
Genetic Therapy for Intervertebral Disc Degeneration
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 4, Pages 1579
Publisher
MDPI AG
Online
2021-02-05
DOI
10.3390/ijms22041579
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
- (2020) Filipe V. Jacinto et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Resveratrol Combined with 17β-Estradiol Prevents IL-1β Induced Apoptosis in Human Nucleus Pulposus Via The PI3K/AKT/Mtor and PI3K/AKT/GSK-3β Pathway
- (2020) Xiaoliang Bai et al. JOURNAL OF INVESTIGATIVE SURGERY
- Therapeutic Potential of Extracellular Vesicles in Degenerative Diseases of the Intervertebral Disc
- (2020) Nathan Piazza et al. Frontiers in Bioengineering and Biotechnology
- In vivo delivery of MMP3-shRNA and Sox9 lentivirus cocktail enhances matrix synthesis to prevent lumbar disc degeneration
- (2020) Zheng Zhao et al. Advances in Clinical and Experimental Medicine
- TRPV4 Inhibition and CRISPR-Cas9 Knockout Reduce Inflammation Induced by Hyperphysiological Stretching in Human Annulus Fibrosus Cells
- (2020) Elena Cambria et al. Cells
- An Injectable Hyaluronan–Methylcellulose (HAMC) Hydrogel Combined with Wharton’s Jelly-Derived Mesenchymal Stromal Cells (WJ-MSCs) Promotes Degenerative Disc Repair
- (2020) Un Yong Choi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of structure and function changes of sensory nervous system in intervertebral disc-related low back pain
- (2020) S. Zhang et al. OSTEOARTHRITIS AND CARTILAGE
- Efficacy of matrilin-3-primed adipose-derived mesenchymal stem cell spheroids in a rabbit model of disc degeneration
- (2020) Manjunatha S. Muttigi et al. Stem Cell Research & Therapy
- Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids Prevent Mesenchymal Stromal-Cell-Derived Chondrocyte Hypertrophy
- (2020) Manjunatha S. Muttigi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of AP-2α/TGF-β1/Smad3 axis in rats with intervertebral disc degeneration
- (2020) Haoxi Li et al. LIFE SCIENCES
- Sustained Release of GDF5 from a Designed Coacervate Attenuates Disc Degeneration in a Rat Model
- (2019) Jian Zhu et al. Acta Biomaterialia
- Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration
- (2019) Niloofar Farhang et al. HUMAN GENE THERAPY
- Tissue Engineering Strategies for Intervertebral Disc Treatment Using Functional Polymers
- (2019) Choi et al. Polymers
- Intervertebral Disc Nucleus Repair: Hype or Hope?
- (2019) Gauri Tendulkar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Delivery of CRISPR/Cas9 for therapeutic genome editing
- (2019) Xiaojie Xu et al. JOURNAL OF GENE MEDICINE
- Gene Therapy
- (2019) Katherine A. High et al. NEW ENGLAND JOURNAL OF MEDICINE
- Towards the scale up of tissue engineered intervertebral discs for clinical application
- (2018) Sarah E. Gullbrand et al. Acta Biomaterialia
- Delivering CRISPR: a review of the challenges and approaches
- (2018) Christopher A. Lino et al. DRUG DELIVERY
- Understanding the molecular biology of intervertebral disc degeneration and potential gene therapy strategies for regeneration: a review
- (2018) Prasanthi Sampara et al. GENE THERAPY
- Delivery approaches for CRISPR/Cas9 therapeutics in vivo: advances and challenges
- (2018) D.C. Luther et al. Expert Opinion on Drug Delivery
- Sustained and Bioresponsive Two-Stage Delivery of Therapeutic miRNA via Polyplex Micelle-Loaded Injectable Hydrogels for Inhibition of Intervertebral Disc Fibrosis
- (2018) Ganjun Feng et al. Advanced Healthcare Materials
- CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation
- (2017) Joshua D. Stover et al. MOLECULAR THERAPY
- Intervertebral Disk Degeneration and Repair
- (2017) James Dowdell et al. NEUROSURGERY
- Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction
- (2017) M. Ito et al. OSTEOARTHRITIS AND CARTILAGE
- CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments
- (2017) Niloofar Farhang et al. TISSUE ENGINEERING PART A
- The PI3K/Akt pathway: a critical player in intervertebral disc degeneration
- (2017) Zhi-Hua Ouyang et al. Oncotarget
- Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study
- (2017) Hemant Kumar et al. Stem Cell Research & Therapy
- Treatment of chronic low back pain – new approaches on the horizon
- (2017) Nebojsa Nick Knezevic et al. Journal of Pain Research
- Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine
- (2017) Yu Moriguchi et al. PLoS One
- Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
- (2016) Chencheng Feng et al. CELL CYCLE
- Molecular mechanisms of cell death in intervertebral disc degeneration (Review)
- (2016) FAN ZHANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Molecular mechanisms of biological aging in intervertebral discs
- (2016) Nam V. Vo et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Current trends in biologics delivery to restore intervertebral disc anabolism
- (2015) Gianluca Fontana et al. ADVANCED DRUG DELIVERY REVIEWS
- Advancing the cellular and molecular therapy for intervertebral disc disease
- (2015) Daisuke Sakai et al. ADVANCED DRUG DELIVERY REVIEWS
- Viral Vectors for Gene Therapy: Translational and Clinical Outlook
- (2015) Melissa A. Kotterman et al. Annual Review of Biomedical Engineering
- Biological Approaches to Treating Intervertebral Disk Degeneration: Devising Stem Cell Therapies
- (2015) Inbo Han et al. CELL TRANSPLANTATION
- Growth and Differentiation Factor-5 Contributes to the Structural and Functional Maintenance of the Intervertebral Disc
- (2015) Chencheng Feng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Anterior cervical corpectomy for cervical spondylotic myelopathy: Reconstruction with expandable cylindrical cage versus iliac crest autograft. A retrospective study
- (2015) Paolo Perrini et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Transplantation of human Wharton’s jelly-derived mesenchymal stem cells highly expressing TGFβ receptors in a rabbit model of disc degeneration
- (2015) Jongchan Ahn et al. Stem Cell Research & Therapy
- The Responses of Autophagy and Apoptosis to Oxidative Stress in Nucleus Pulposus Cells: Implications for Disc Degeneration
- (2014) Jiang-Wei Chen et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Vertebral endplate change as a feature of intervertebral disc degeneration: a heritability study
- (2014) Juhani H. Määttä et al. EUROPEAN SPINE JOURNAL
- Blocking the Function of Inflammatory Cytokines and Mediators by Using IL-10 and TGF-β: A Potential Biological Immunotherapy for Intervertebral Disc Degeneration in a Beagle Model
- (2014) Wei Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Gene therapy for cardiovascular disease mediated by ultrasound and microbubbles
- (2013) Zhi-Yi Chen et al. Cardiovascular Ultrasound
- Synergistic Effect of Combined Growth Factors in Porcine Intervertebral Disc Degeneration
- (2013) Hongsik Cho et al. CONNECTIVE TISSUE RESEARCH
- Role of cytokines in intervertebral disc degeneration: pain and disc content
- (2013) Makarand V. Risbud et al. Nature Reviews Rheumatology
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?
- (2013) James C. Iatridis et al. Spine Journal
- The molecular basis of intervertebral disc degeneration
- (2013) Christopher K. Kepler et al. Spine Journal
- Functional Multipotency of Stem Cells: A Conceptual Review of Neurotrophic Factor-Based Evidence and Its Role in Translational Research
- (2011) Yang D et al. Current Neuropharmacology
- Ultrasound Exposure of Lipoplex Loaded Microbubbles Facilitates Direct Cytoplasmic Entry of the Lipoplexes
- (2009) Ine Lentacker et al. MOLECULAR PHARMACEUTICS
- The promises and pitfalls of RNA-interference-based therapeutics
- (2009) Daniela Castanotto et al. NATURE
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model
- (2009) Shoji Seki et al. ARTHRITIS RESEARCH & THERAPY
- Ultrasound-Targeted Gene Delivery Induces Angiogenesis After a Myocardial Infarction in Mice
- (2009) Hiroko Fujii et al. JACC-Cardiovascular Imaging
- Gene therapy approach for disc degeneration and associated spinal disorders
- (2008) Kotaro Nishida et al. EUROPEAN SPINE JOURNAL
- Tissue engineering and the intervertebral disc: the challenges
- (2008) Rita Kandel et al. EUROPEAN SPINE JOURNAL
- Biological repair of the degenerated intervertebral disc by the injection of growth factors
- (2008) Koichi Masuda EUROPEAN SPINE JOURNAL
- Stem cell–mediated regeneration of the intervertebral disc: cellular and molecular challenges
- (2008) Rahul Jandial et al. Neurosurgical Focus
- Molecular Changes in the Degenerated Goat Intervertebral Disc
- (2008) Roel Hoogendoorn et al. SPINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now