Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice

Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses

(2020) Shuixian Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Potential interaction between lysophosphatidic acid and tumor-associated macrophages in ovarian carcinoma

(2020) Ying Feng et al.   Journal of Inflammation-London

PRP1, a heteropolysaccharide from Platycodonis Radix, induced apoptosis of HepG2 cells via regulating miR-21-mediated PI3K/AKT pathway

(2020) Jia-Qi He et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

ARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway

(2020) Pengfei Li et al.   Cancer Management and Research

Cisplatin-Membrane Interactions and Their Influence on Platinum Complexes Activity and Toxicity

(2019) Nuno Martinho et al.   Frontiers in Physiology

Thioridazine Sensitizes Cisplatin Against Chemoresistant Human Lung and Ovary Cancer Cells

(2019) Guanhua Qian et al.   DNA AND CELL BIOLOGY

Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

(2019) Xiaocheng Cao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Efficacy and Safety of First-Line Carboplatin- versus Cisplatin-based Chemotherapy for Non-Small Cell Lung Cancer: A Meta-Analysis

(2019) Frank Griesinger et al.   LUNG CANCER

Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer

(2019) Onsurang Wattanathamsan et al.   PHYTOTHERAPY RESEARCH

Loss of PKM2 in Lgr5+ intestinal stem cells promotes colitis-associated colorectal cancer

(2019) Yeji Kim et al.   Scientific Reports

Systemic Therapy for Locally Advanced and Metastatic Non–Small Cell Lung Cancer

(2019) Kathryn C. Arbour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

(2019) Xinming Jing et al.   Molecular Cancer

Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

(2019) Bingrun Liu et al.   Frontiers in Immunology

Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis

(2019) Xiao Liang et al.   Cancer Management and Research

Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy

(2019) Ali F. Abdel-Wahab et al.   PHARMACOLOGICAL RESEARCH

Isovitexin (IV) induces apoptosis and autophagy in liver cancer cells through endoplasmic reticulum stress

(2018) Sheng-Xiang Lv et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PKM2, a potential target for regulating cancer

(2018) Yu-huan Li et al.   GENE

Heat treatment improves the immunomodulatory and cellular antioxidant behavior of a natural flavanone: Eriodictyol

(2018) Rihab Khlifi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells

(2018) Cian-Song Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isovitexin alleviates liver injury induced by lipopolysaccharide/ d -galactosamine by activating Nrf2 and inhibiting NF-κB activation

(2018) Jian-jian Hu et al.   MICROBIAL PATHOGENESIS

Anti-Inflammatory Activities of Compounds Isolated from the Rhizome of Anemarrhena asphodeloides

(2018) Zeyuan Wang et al.   MOLECULES

Water extract of ginseng and astragalus regulates macrophage polarization and synergistically enhances DDP's anticancer effect

(2018) Yingna Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Knockdown of BRCA2 enhances cisplatin and cisplatin-induced autophagy in ovarian cancer cells

(2017) Biao Wan et al.   ENDOCRINE-RELATED CANCER

Role of chemotherapy and targeted therapy in early-stage non-small cell lung cancer

(2017) Misako Nagasaka et al.   Expert Review of Anticancer Therapy

Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis

(2017) Shuhua Shan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Platinum-based drugs: past, present and future

(2016) Shahana Dilruba et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

PKM2, cancer metabolism, and the road ahead

(2016) Talya L Dayton et al.   EMBO REPORTS

Pharmacokinetic profiles of cancer sonochemotherapy

(2016) Ying Zhang et al.   Expert Opinion on Drug Delivery

Platinum-based chemotherapy in advanced non-small-cell lung cancer: optimal number of treatment cycles

(2016) Antonio Rossi et al.   Expert Review of Anticancer Therapy

A review on the pharmacological effects of vitexin and isovitexin

(2016) Miao He et al.   FITOTERAPIA

Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways

(2016) Hongming Lv et al.   International Journal of Biological Sciences

Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture

(2015) Tianfu Dong et al.   BIOMEDICINE & PHARMACOTHERAPY

In Vitro Effects of Some Flavones on Human Pyruvate Kinase Isoenzyme M2

(2014) Erdem Aslan et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Antitumor and immunomodulatory effects of a water-soluble polysaccharide from Lilii Bulbus in mice

(2013) Xin Sun et al.   CARBOHYDRATE POLYMERS