Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

Hepatic Macrophages in Liver Injury

(2020) Zhao Shan et al.   Frontiers in Immunology

TAZ stimulates liver regeneration through interleukin-6–induced hepatocyte proliferation and inhibition of cell death after liver injury

(2019) A Rum Kim et al.   FASEB JOURNAL

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

(2019) Lara Planas-Paz et al.   Cell Stem Cell

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

(2019) Brian J. Pepe-Mooney et al.   Cell Stem Cell

Comparison of the Opn-CreER and Ck19-CreER Drivers in Bile Ducts of Normal and Injured Mouse Livers

(2019) Lesaffer et al.   Cells

A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling

(2019) Weiping Li et al.   Cell Stem Cell

Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells

(2019) Masakazu Hashimoto et al.   DEVELOPMENTAL CELL

CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization

(2019) Meng Li et al.   Cellular & Molecular Immunology

Hepatocyte Stress Increases Expression of YAP and TAZ in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis

(2019) Meghan Mooring et al.   HEPATOLOGY

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

(2019) Iván M. Moya et al.   SCIENCE

Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes

(2018) Seh-Hoon Oh et al.   JOURNAL OF HEPATOLOGY

Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids

(2018) Marianne Wammers et al.   Scientific Reports

Pregnane X Receptor Regulates Liver Size and Liver Cell Fate via Yes-associated Protein Activation

(2018) Yiming Jiang et al.   HEPATOLOGY

Axis of serotonin -pERK-YAP in liver regeneration

(2018) Yu Fang et al.   LIFE SCIENCES

Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection

(2018) Elisabeth Lang et al.   Scientific Reports

CEACAM1 in Liver Injury, Metabolic and Immune Regulation

(2018) Andrea Horst et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

(2018) Iván M. Moya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PPARα activation protects against cholestatic liver injury

(2017) Qi Zhao et al.   Scientific Reports

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2

(2016) Giulio Loforese et al.   EMBO Molecular Medicine

Hedgehog regulates yes-associated protein 1 in regenerating mouse liver

(2016) Marzena Swiderska-Syn et al.   HEPATOLOGY

Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ

(2016) Jing Yi et al.   HEPATOLOGY

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

(2016) Andrew G. Cox et al.   NATURE CELL BIOLOGY

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

(2016) Fuqin Fan et al.   Science Translational Medicine

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

(2016) Charlotte L. Scott et al.   Nature Communications

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

(2015) Julien Fitamant et al.   Cell Reports

Two-signal requirement for growth-promoting function of Yap in hepatocytes

(2015) Tian Su et al.   eLife

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis

(2014) Seddik Hammad et al.   ARCHIVES OF TOXICOLOGY

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Mechanisms of coagulative necrosis in malignant epithelial tumors (Review)

(2014) ROSARIO A. CARUSO et al.   Oncology Letters

Bile acid receptors as targets for drug development

(2013) Frank G. Schaap et al.   Nature Reviews Gastroenterology & Hepatology

Yes-associated protein regulates the hepatic response after bile duct ligation

(2012) Haibo Bai et al.   HEPATOLOGY

Abcb11Deficiency Induces Cholestasis Coupled to Impaired β-Fatty Acid Oxidation in Mice

(2012) Yuanyuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Chemokines in Acute Liver Injury

(2012) Yedidya Saiman et al.   Frontiers in Physiology

Changes of Organic Anion Transporter MRP4 and Related Nuclear Receptors in Human Obstructive Cholestasis

(2011) Jin Chai et al.   JOURNAL OF GASTROINTESTINAL SURGERY

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Pregnane X Receptor Is SUMOylated to Repress the Inflammatory Response

(2010) G. Hu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The PXR is a drug target for chronic inflammatory liver disease

(2010) Karen Wallace et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY