Di-(2-ethylhexyl) phthalate-induced hepatotoxicity exacerbated type 2 diabetes mellitus (T2DM) in female pubertal T2DM mice

Late Relapse of Diabetes After Bariatric Surgery: Not Rare, but Not a Failure

(2020) Ali Aminian et al.   DIABETES CARE

Healthy Effects of Plant Polyphenols: Molecular Mechanisms

(2020) Manuela Leri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Typical neurobehavioral methods and transcriptome analysis reveal the neurotoxicity and mechanisms of di(2-ethylhexyl) phthalate on pubertal male ICR mice with type 2 diabetes mellitus

(2020) Weiwei Feng et al.   ARCHIVES OF TOXICOLOGY

Healthspan Maintenance and Prevention of Parkinson’s-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans

(2020) Giovanni Brunetti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of c-Jun N-terminal Kinase (JNK) in Obesity and Type 2 Diabetes

(2020) Justin Hou Ming Yung et al.   Cells

Glyphosate exposure induces inflammatory responses in the small intestine and alters gut microbial composition in rats

(2020) Qian Tang et al.   ENVIRONMENTAL POLLUTION

Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson’s Models

(2020) Gabriele Di Rosa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Use of integrated biomarker response for evaluating antioxidant stress and DNA damage of earthworms (Eisenia fetida) in decabromodiphenyl ethane-contaminated soil

(2020) Yiyi Zhao et al.   ENVIRONMENTAL POLLUTION

Short-term and persistent impacts of sublethal exposure to diazepam on behavioral traits and brain GABA levels in juvenile zebrafish (Danio rerio)

(2020) Min Wu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson’s Disease in Mice

(2020) Rosalba Siracusa et al.   Antioxidants

Impacts of chronic exposure to sublethal diazepam on behavioral traits of female and male zebrafish (Danio rerio)

(2020) Kun Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity

(2019) Yuanyuan Huang et al.   International Journal of Environmental Research and Public Health

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

GABA-containing compound gammapyrone protects against brain impairments in Alzheimer’s disease model male rats and prevents mitochondrial dysfunction in cell culture

(2019) Vladimirs Pilipenko et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Combined toxicities of tributyltin and polychlorinated biphenyls on the development and hatching of Japanese medaka (Oryzias latipes) embryos via in ovo nanoinjection

(2019) Xuchun Qiu et al.   CHEMOSPHERE

Study on the Metabolism Toxicity, Susceptibility and Mechanism of Di-(2-ethylhexyl) Phthalate on Rat Liver BRL Cells with Insulin resistance in vitro

(2019) Yangyang Ding et al.   TOXICOLOGY

Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes

(2019) Brian Finan et al.   DIABETES

Phthalate exposure and metabolic effects: a systematic review of the human epidemiological evidence

(2019) Elizabeth G. Radke et al.   ENVIRONMENT INTERNATIONAL

A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK Signaling Pathways

(2019) Shi-Jun Yue et al.   MOLECULES

Effects of in utero and lactational exposure to phthalates on reproductive development and glycemic homeostasis in rats

(2019) Amanda Caroline Venturelli et al.   TOXICOLOGY

Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

(2019) Chi-Chuan Lin et al.   CANCER LETTERS

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Mothers and children are related, even in exposure to chemicals present in common consumer products

(2019) Gudrun Koppen et al.   ENVIRONMENTAL RESEARCH

Beyond Phthalate Diesters: Existence of Phthalate Monoesters in South China House Dust and Implications for Human Exposure

(2019) Xiaotu Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Di-(2-ethylhexyl)-phthalate induces apoptosis via the PPARγ/PTEN/AKT pathway in differentiated human embryonic stem cells

(2019) Haiqin Fang et al.   FOOD AND CHEMICAL TOXICOLOGY

Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus

(2019) Yangyang Ding et al.   ARCHIVES OF TOXICOLOGY

The effects of long-term exposure to low doses of cadmium on the health of the next generation of mice

(2019) Tianfeng Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Urinary levels of phthalate metabolites and their association with lifestyle behaviors in Chinese adolescents and young adults

(2019) Shuang Ding et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions

(2018) Sophie Miquel et al.   AGEING RESEARCH REVIEWS

Gender differences in mercury-induced hepatotoxicity: Potential mechanisms

(2018) María Herminia Hazelhoff et al.   CHEMOSPHERE

Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

(2018) Vittorio Calabrese et al.   FREE RADICAL BIOLOGY AND MEDICINE

Foetal-neonatal exposure of Di (2-ethylhexyl) phthalate disrupts ovarian development in mice by inducing autophagy

(2018) Yan Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Environmental toxicology and omics: A question of sex

(2018) Xuefang Liang et al.   Journal of Proteomics

Interplay of gender, age and drug properties on reporting frequency of drug-induced liver injury

(2018) Nayana George et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The associations between phthalate exposure and insulin resistance, β-cell function and blood glucose control in a population-based sample

(2018) Robert Edgar Dales et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Environmental Risk Factors for Developing Type 2 Diabetes Mellitus: A Systematic Review

(2018) Tashi Dendup et al.   International Journal of Environmental Research and Public Health

Protective Actions of Anserine Under Diabetic Conditions

(2018) Verena Peters et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hormetic approaches to the treatment of Parkinson's disease: Perspectives and possibilities

(2018) Vittorio Calabrese et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dietary fish oil supplementation during early pregnancy in rats on a cafeteria-diet prevents fatty liver in adult male offspring

(2018) Clara Sánchez-Blanco et al.   FOOD AND CHEMICAL TOXICOLOGY

Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane

(2018) Reza Farmahin et al.   FOOD AND CHEMICAL TOXICOLOGY

Phthalates exposure as determinant of albuminuria in type 2 diabetes subjects: a cross-sectional study

(2018) Alessandro Mengozzi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury

(2018) Maria Ruart et al.   JOURNAL OF HEPATOLOGY

New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis

(2018) Ting Yuan et al.   Redox Biology

Exposure to phthalates in patients with diabetes and its association with oxidative stress, adiponectin, and inflammatory cytokines

(2017) Yishuang Duan et al.   ENVIRONMENT INTERNATIONAL

Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketotic cows

(2017) Xiliang Du et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Phthalates impact human health: Epidemiological evidences and plausible mechanism of action

(2017) Sailas Benjamin et al.   JOURNAL OF HAZARDOUS MATERIALS

JNK at the crossroad of obesity, insulin resistance, and cell stress response

(2017) Giovanni Solinas et al.   Molecular Metabolism

Di (2-ethylhexyl) phthalate impairs steroidogenesis in ovarian follicular cells of prepuberal mice

(2016) Fang-Nong Lai et al.   ARCHIVES OF TOXICOLOGY

Occupational exposure to phthalates in relation to gender, consumer practices and body composition

(2016) Ida Petrovičová et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Di(2-ethylhexyl) phthalate exacerbates non-alcoholic fatty liver in rats and its potential mechanisms

(2016) Hao Chen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Toxicity and bioaccumulation of copper in Limnodrilus hoffmeisteri under different pH values: Impacts of perfluorooctane sulfonate

(2016) Lingjun Meng et al.   JOURNAL OF HAZARDOUS MATERIALS

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Phthalate esters in the environment: A critical review of their occurrence, biodegradation, and removal during wastewater treatment processes

(2016) Da-Wen Gao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Achievement of Dual Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein Targets More Frequent With the Addition of Ezetimibe to Simvastatin and Associated With Better Outcomes in IMPROVE-ITCLINICAL PERSPECTIVES

(2015) Erin A. Bohula et al.   CIRCULATION

The Future of Treating Youth-Onset Type 2 Diabetes: Focusing Upstream and Extending Our Influence into Community Environments

(2015) Shazhan Amed   Current Diabetes Reports

A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry

(2015) Longfei Lin et al.   JOURNAL OF HAZARDOUS MATERIALS

Metabolic Outcome of Female Mice Exposed to a Mixture of Low-Dose Pollutants in a Diet-Induced Obesity Model

(2015) Danielle Naville et al.   PLoS One

Sex differences in metabolic homeostasis, diabetes, and obesity

(2015) Franck Mauvais-Jarvis   Biology of Sex Differences

Type 2 Diabetic Rats on Diet Supplemented With Chromium Malate Show Improved Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism

(2015) Weiwei Feng et al.   PLoS One

Hepatoprotective effect of silymarin on di(2-ethylhexyl)phthalate (DEHP) induced injury in liver FL83B cells

(2014) Diana Lo et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Predator cues magnify effects of the pesticide endosulfan in water bugs in a multi-species test in outdoor containers

(2013) Hendrik Trekels et al.   AQUATIC TOXICOLOGY

Taiwan food scandal: The illegal use of phthalates as a clouding agent and their contribution to maternal exposure

(2013) Justin Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Estrogen: A master regulator of bioenergetic systems in the brain and body

(2013) Jamaica R. Rettberg et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action

(2013) C. Lindtner et al.   Science Translational Medicine

Species and inter-individual differences in metabolic capacity of di(2-ethylhexyl)phthalate (DEHP) between human and mouse livers

(2013) Yuki Ito et al.   Environmental Health and Preventive Medicine

Sex differences in mesenteric endothelial function of streptozotocin-induced diabetic rats: a shift in the relative importance of EDRFs

(2012) Rui Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Curcumin Extract for Prevention of Type 2 Diabetes

(2012) S. Chuengsamarn et al.   DIABETES CARE

Effects of Di(2-ethylhexyl) Phthalate (DEHP) on Female Fertility and Adipogenesis in C3H/N Mice

(2012) Juliane-Susanne Schmidt et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Vascular Disease in Diabetic Women: Why Do They Miss the Female Protection?

(2012) Ana Paula Villela Dantas et al.   Experimental Diabetes Research

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

(2010) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

(2010) Karima Begriche et al.   JOURNAL OF HEPATOLOGY

Extranuclear estrogen receptor-  stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

(2010) W. P. S. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism