The immune landscape of neuroblastoma: Challenges and opportunities for novel therapeutic strategies in pediatric oncology
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Title
The immune landscape of neuroblastoma: Challenges and opportunities for novel therapeutic strategies in pediatric oncology
Authors
Keywords
Neuroblastoma, Tumour immunology, Immunotherapy, Tumour microenvironment, T cells, NK cells, Tumour immune evasion
Journal
EUROPEAN JOURNAL OF CANCER
Volume 144, Issue -, Pages 123-150
Publisher
Elsevier BV
Online
2020-12-18
DOI
10.1016/j.ejca.2020.11.014
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- (2020) Priti S. Hegde et al. IMMUNITY
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- (2020) Edward A. Stadtmauer et al. SCIENCE
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- (2020) Suzanne L. Topalian et al. SCIENCE
- Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies
- (2020) Dana L. Casey et al. Cancer Immunology Research
- Monitoring Immune Responses in Neuroblastoma Patients during Therapy
- (2020) Celina L. Szanto et al. Cancers
- Investigation of the Role of Dinutuximab Beta-Based Immunotherapy in the SIOPEN High-Risk Neuroblastoma 1 Trial (HR-NBL1)
- (2020) Ladenstein et al. Cancers
- CAMKV Is a Candidate Immunotherapeutic Target in MYCN Amplified Neuroblastoma
- (2020) Robyn T. Sussman et al. Frontiers in Oncology
- Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
- (2020) Theodore L. Roth et al. CELL
- Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
- (2020) Malkiel A. Cohen et al. Cell Stem Cell
- Long-term follow up of lifileucel (LN-144) cryopreserved autologous tumor infiltrating lymphocyte therapy in patients with advanced melanoma progressed on multiple prior therapies.
- (2020) Amod Sarnaik et al. JOURNAL OF CLINICAL ONCOLOGY
- Targets and Antibody Formats for Immunotherapy of Neuroblastoma
- (2020) Jeong A. Park et al. JOURNAL OF CLINICAL ONCOLOGY
- A conserved dendritic-cell regulatory program limits antitumour immunity
- (2020) Barbara Maier et al. NATURE
- A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
- (2020) Michal Slyper et al. NATURE MEDICINE
- Control of brain tumor growth by reactivating myeloid cells with niacin
- (2020) Susobhan Sarkar et al. Science Translational Medicine
- Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
- (2020) Constance J. Martin et al. Science Translational Medicine
- Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy
- (2020) Maud Mayoux et al. Science Translational Medicine
- Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
- (2020) Joseph D. Butner et al. Science Advances
- Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial
- (2020) Rosa Nguyen et al. Journal for ImmunoTherapy of Cancer
- Nivolumab and dinutuximab beta in two patients with refractory neuroblastoma
- (2020) Karoline Ehlert et al. Journal for ImmunoTherapy of Cancer
- CD200 is overexpressed in neuroblastoma and regulates tumor immune microenvironment
- (2020) Chao Xin et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor‐stroma drug targeting
- (2020) Anna Kock et al. FASEB JOURNAL
- Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors
- (2020) Lorenzo Galluzzi et al. Nature Reviews Clinical Oncology
- News on immune checkpoint inhibitors as immunotherapy strategies in adult and pediatric solid tumors
- (2020) Ombretta Melaiu et al. SEMINARS IN CANCER BIOLOGY
- MHC Class I Downregulation in Cancer: Underlying Mechanisms and Potential Targets for Cancer Immunotherapy
- (2020) Annelisa M. Cornel et al. Cancers
- Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis
- (2020) Andras Heczey et al. NATURE MEDICINE
- Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation
- (2019) Kazuaki Harada et al. CANCER SCIENCE
- The BET-bromodomain inhibitor JQ1 renders neuroblastoma cells more resistant to NK cell-mediated recognition and killing by downregulating ligands for NKG2D and DNAM1 receptors
- (2019) Irene Veneziani et al. Oncotarget
- Engineering the TGFβ receptor to Enhance the Therapeutic Potential of Natural Killer Cells as an Immunotherapy for Neuroblastoma
- (2019) Rachel A Burga et al. CLINICAL CANCER RESEARCH
- Anti-CD105 Antibody Eliminates Tumor Microenvironment Cells and Enhances Anti-GD2 Antibody Immunotherapy of Neuroblastoma with Activated Natural Killer Cells
- (2019) Hong-Wei Wu et al. CLINICAL CANCER RESEARCH
- Safety and efficacy of adoptive cell transfer using autologous tumor infiltrating lymphocytes (LN-145) for treatment of recurrent, metastatic, or persistent cervical carcinoma.
- (2019) Amir A. Jazaeri et al. JOURNAL OF CLINICAL ONCOLOGY
- Anti-tumor activity and tolerability of hu14.18-IL2 with GMCSF and isotretinoin in recurrent or refractory neuroblastoma: A Children's Oncology Group phase II study
- (2019) Suzanne Shusterman et al. CLINICAL CANCER RESEARCH
- Diminished cytolytic activity of γδ T cells with reduced DNAM-1 expression in neuroblastoma patients
- (2019) Xiaolin Wang et al. CLINICAL IMMUNOLOGY
- Supercharging adoptive T cell therapy to overcome solid tumor–induced immunosuppression
- (2019) Sherly Mardiana et al. Science Translational Medicine
- Location, location, location: Tissue resident memory T cells in mice and humans
- (2019) Peter A. Szabo et al. Science Immunology
- In vivo modelling of chemo-resistant neuroblastoma provides new insights into chemo-refractory disease and metastasis.
- (2019) Orli Yogev et al. CANCER RESEARCH
- Tumor infiltrating lymphocytes expanded from pediatric neuroblastoma display heterogeneity of phenotype and function
- (2019) Marina Ollé Hurtado et al. PLoS One
- Cell-Laden Hydrogel as a Clinical-Relevant 3D Model for Analyzing Neuroblastoma Growth, Immunophenotype, and Susceptibility to Therapies
- (2019) Alessandra Marrella et al. Frontiers in Immunology
- Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors
- (2019) Rachel Grosser et al. CANCER CELL
- CAR-NK for tumor immunotherapy: Clinical transformation and future prospects
- (2019) Wenxiu Wang et al. CANCER LETTERS
- Dendritic Cell-Based Immunotherapy in Advanced Sarcoma and Neuroblastoma Pediatric Patients: Anti-cancer Treatment Preceding Monocyte Harvest Impairs the Immunostimulatory and Antigen-Presenting Behavior of DCs and Manufacturing Process Outcome
- (2019) Eva Hlavackova et al. Frontiers in Oncology
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- (2019) Young Bae Choi et al. PLoS One
- Cellular components in tumor microenvironment of neuroblastoma and the prognostic value
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- (2019) Julie Voeller et al. Journal for ImmunoTherapy of Cancer
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- (2018) Susanne N. Gröbner et al. NATURE
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- (2018) Filippo Veglia et al. NATURE IMMUNOLOGY
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- (2018) Priya Srinivasan et al. PLOS MEDICINE
- A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children’s Oncology Group Study ANBL0931
- (2018) M. Fevzi Ozkaynak et al. Frontiers in Immunology
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- (2018) Lotte Spel et al. CANCER RESEARCH
- Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
- (2018) Noam Auslander et al. NATURE MEDICINE
- The hallmarks of successful anticancer immunotherapy
- (2018) Lorenzo Galluzzi et al. Science Translational Medicine
- Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis
- (2018) Xian Shen et al. BMJ-British Medical Journal
- Immune landscape and in vivo immunogenicity of NY-ESO-1 tumor antigen in advanced neuroblastoma patients
- (2018) Chiara Camisaschi et al. BMC CANCER
- Microenvironment in neuroblastoma: isolation and characterization of tumor-derived mesenchymal stromal cells
- (2018) Gloria Pelizzo et al. BMC CANCER
- Organoid Modeling of the Tumor Immune Microenvironment
- (2018) James T. Neal et al. CELL
- Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial
- (2018) Ruth Ladenstein et al. LANCET ONCOLOGY
- CAR T Cell Therapy for Neuroblastoma
- (2018) Rebecca M. Richards et al. Frontiers in Immunology
- Secretory High-Mobility Group Box 1 Protein Affects Regulatory T Cell Differentiation in Neuroblastoma Microenvironment In Vitro
- (2018) Thitinee Vanichapol et al. Journal of Oncology
- Sequential actions of immune effector cells induced by viral activation of dendritic cells to eliminate murine neuroblastoma
- (2017) Naonori Kawakubo et al. JOURNAL OF PEDIATRIC SURGERY
- Irinotecan–temozolomide with temsirolimus or dinutuximab in children with refractory or relapsed neuroblastoma (COG ANBL1221): an open-label, randomised, phase 2 trial
- (2017) Rajen Mody et al. LANCET ONCOLOGY
- CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma
- (2017) Andras Heczey et al. MOLECULAR THERAPY
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- Invariant natural killer T infiltration in neuroblastoma with favorable outcome
- (2017) Tomoro Hishiki et al. PEDIATRIC SURGERY INTERNATIONAL
- Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma
- (2017) Valentina Rigo et al. Scientific Reports
- The State of Cellular Adoptive Immunotherapy for Neuroblastoma and Other Pediatric Solid Tumors
- (2017) Thanh-Phuong Le et al. Frontiers in Immunology
- MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET Database
- (2017) Peng Zhang et al. Frontiers in Immunology
- Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
- (2017) Julian P. Layer et al. OncoImmunology
- PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD2 antibody ch14.18/CHO
- (2017) Nikolai Siebert et al. OncoImmunology
- MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma
- (2017) Elisa Brandetti et al. OncoImmunology
- TGFβR1 Blockade with Galunisertib (LY2157299) Enhances Anti-Neuroblastoma Activity of the Anti-GD2 Antibody Dinutuximab (ch14.18) with Natural Killer Cells
- (2016) Hung C. Tran et al. CLINICAL CANCER RESEARCH
- Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma
- (2016) Y. Mao et al. CLINICAL CANCER RESEARCH
- KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma
- (2016) Christopher J. Forlenza et al. JOURNAL OF CLINICAL ONCOLOGY
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- Involvement of IL-10 and TGF-β in HLA-E-mediated neuroblastoma migration and invasion
- (2016) Zijun Zhen et al. Oncotarget
- Soluble HLA-G and HLA-E Levels in Bone Marrow Plasma Samples Are Related to Disease Stage in Neuroblastoma Patients
- (2016) Fabio Morandi et al. Journal of Immunology Research
- Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma
- (2016) Gabriele Büchel et al. OncoImmunology
- Neuroblastoma patients with high-affinity FCGR2A, -3A and stimulatory KIR 2DS2 treated by long-term infusion of anti-GD2 antibody ch14.18/CHO show higher ADCC levels and improved event-free survival
- (2016) Nikolai Siebert et al. OncoImmunology
- Neuroblastoma
- (2016) Katherine K. Matthay et al. Nature Reviews Disease Primers
- A phase I trial combining decitabine/dendritic cell vaccine targeting MAGE-A1, MAGE-A3 and NY-ESO-1 for children with relapsed or therapy-refractory neuroblastoma and sarcoma
- (2015) Deepa K. Krishnadas et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- TLR3 triggering regulates PD-L1 (CD274) expression in human neuroblastoma cells
- (2015) Marianne Boes et al. CANCER LETTERS
- Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity
- (2015) F. Mussai et al. CANCER RESEARCH
- Advances in Risk Classification and Treatment Strategies for Neuroblastoma
- (2015) Navin R. Pinto et al. JOURNAL OF CLINICAL ONCOLOGY
- A Phase I Study of the Anti-Idiotype Vaccine Racotumomab in Neuroblastoma and Other Pediatric Refractory Malignancies
- (2015) Walter Cacciavillano et al. PEDIATRIC BLOOD & CANCER
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients
- (2015) Michaela Semeraro et al. Science Translational Medicine
- Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma
- (2015) Lotte Spel et al. Oncotarget
- Expression ofFOXP3,CD14, andARG1in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival
- (2015) Sara Stigliani et al. Biomed Research International
- IL-10 and ARG-1 Concentrations in Bone Marrow and Peripheral Blood of Metastatic Neuroblastoma Patients Do Not Associate with Clinical Outcome
- (2015) Fabio Morandi et al. Journal of Immunology Research
- Natural killer cell mediated immunosurveillance of pediatric neuroblastoma
- (2015) Michaela Semeraro et al. OncoImmunology
- Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma
- (2015) Marco Mina et al. OncoImmunology
- PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance
- (2015) Alessandra Dondero et al. OncoImmunology
- PD-L1 and CD8+PD1+lymphocytes exist as targets in the pediatric tumor microenvironment for immunomodulatory therapy
- (2015) Ferdousi Chowdhury et al. OncoImmunology
- Phase I Trial of a Bivalent Gangliosides Vaccine in Combination with β-Glucan for High-Risk Neuroblastoma in Second or Later Remission
- (2014) Brian H. Kushner et al. CLINICAL CANCER RESEARCH
- Expression of Macrophage Migration Inhibitory Factor by Neuroblastoma Leads to the Inhibition of Antitumor T Cell Reactivity In Vivo
- (2014) Q. Zhou et al. JOURNAL OF IMMUNOLOGY
- Immunoglobulin GM and FcγRIIIa genotypes influence cytotoxicity of neuroblastoma cells
- (2014) Janardan P. Pandey et al. JOURNAL OF NEUROIMMUNOLOGY
- Circulating T-Regulatory Cells in Neuroblastoma: A Pilot Prospective Study
- (2014) TVSVGK Tilak et al. PEDIATRIC HEMATOLOGY AND ONCOLOGY
- ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment
- (2014) G Bianchi et al. Cell Death & Disease
- Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches
- (2014) Cristina Bottino et al. Frontiers in Immunology
- Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+ T and NK cells and improves survival
- (2013) Richard K. Yang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Low-dose aspirin delays an inflammatory tumor progression in vivo in a transgenic mouse model of neuroblastoma
- (2013) Lena-Maria Carlson et al. CARCINOGENESIS
- Polyphenol E Enhances the Antitumor Immune Response in Neuroblastoma by Inactivating Myeloid Suppressor Cells
- (2013) G. Santilli et al. CLINICAL CANCER RESEARCH
- Immunomodulatory Monoclonal Antibodies Combined with Peptide Vaccination Provide Potent Immunotherapy in an Aggressive Murine Neuroblastoma Model
- (2013) E. L. Williams et al. CLINICAL CANCER RESEARCH
- The immune environment of paediatric solid malignancies: evidence from an immunohistochemical study of clinical cases
- (2013) John R. Apps et al. Fetal and Pediatric Pathology
- Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
- (2013) Gabriela Bindea et al. IMMUNITY
- A transplantable TH-MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma
- (2013) Michiel Kroesen et al. INTERNATIONAL JOURNAL OF CANCER
- The genetic landscape of high-risk neuroblastoma
- (2013) Trevor J Pugh et al. NATURE GENETICS
- The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes
- (2013) Lena-Maria Carlson et al. OncoImmunology
- Neuroblastoma-related inflammation
- (2013) Lena-Maria Carlson et al. OncoImmunology
- Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment
- (2012) Nidale Tarek et al. JOURNAL OF CLINICAL INVESTIGATION
- Examining T Cells at Vaccine Sites of Tumor-bearing Hosts Provides Insights to Dysfunctional T-Cell Immunity
- (2012) Kristen M. Barr et al. JOURNAL OF IMMUNOTHERAPY
- Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
- (2011) C. U. Louis et al. BLOOD
- Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy
- (2011) Thorsten Simon et al. BMC CANCER
- Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments
- (2011) Rocio Soldati et al. INTERNATIONAL JOURNAL OF CANCER
- NK Cell immunotherapy for high-risk neuroblastoma relapse after haploidentical HSCT
- (2011) Justyna Kanold et al. PEDIATRIC BLOOD & CANCER
- Genotypes of NK Cell KIR Receptors, Their Ligands, and Fc Receptors in the Response of Neuroblastoma Patients to Hu14.18-IL2 Immunotherapy
- (2010) D. C. Delgado et al. CANCER RESEARCH
- Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma
- (2010) Alice L. Yu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interferon- -Dependent Infiltration of Human T Cells into Neuroblastoma Tumors In vivo
- (2009) G. S.D. Reid et al. CLINICAL CANCER RESEARCH
- Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
- (2009) Liping Song et al. JOURNAL OF CLINICAL INVESTIGATION
- Differentiation induced by physiological and pharmacological stimuli leads to increased antigenicity of human neuroblastoma cells
- (2008) Lena-Maria Carlson et al. CELL RESEARCH
- Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule
- (2008) A Gregorio et al. HISTOPATHOLOGY
- A Phase 1/2 Study of Autologous Neuroblastoma Tumor Cells Genetically Modified to Secrete IL-2 in Patients With High-risk Neuroblastoma
- (2008) Heidi V. Russell et al. JOURNAL OF IMMUNOTHERAPY
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- (2008) Martin A Pule et al. NATURE MEDICINE
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