Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition

(2020) Magdalena Marek et al.   JOURNAL OF CELL BIOLOGY

Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins

(2020) Joshua A. Lees et al.   CURRENT OPINION IN CELL BIOLOGY

Aster proteins regulate the accessible cholesterol pool in the plasma membrane

(2020) Alessandra Ferrari et al.   MOLECULAR AND CELLULAR BIOLOGY

Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

(2020) Michael N. Trinh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol Handling in Lysosomes and Beyond

(2020) Ying Meng et al.   TRENDS IN CELL BIOLOGY

Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions

(2019) Summer B. Thyme et al.   CELL

Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes

(2019) Shreya Endapally et al.   CELL

SMP domain proteins in membrane lipid dynamics

(2019) Darshini Jeyasimman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Specialized ER membrane domains for lipid metabolism and transport

(2019) Taki Nishimura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum

(2019) Kristen A. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The functional universe of membrane contact sites

(2019) William A. Prinz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex

(2019) Tomoki Naito et al.   eLife

Exchange of water for sterol underlies sterol egress from a StARkin domain

(2019) George Khelashvili et al.   eLife

The Oxysterol-Binding Protein Cycle: Burning Off PI(4)P to Transport Cholesterol

(2018) Bruno Antonny et al.   Annual Review of Biochemistry

Retrospective on Cholesterol Homeostasis: The Central Role of Scap

(2018) Michael S. Brown et al.   Annual Review of Biochemistry

Structural insights into a StART-like domain in Lam4 and its interaction with sterol ligands

(2018) Alberto T. Gatta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular basis for sterol transport by StART‐like lipid transfer domains

(2018) Florian A Horenkamp et al.   EMBO JOURNAL

Structural basis of sterol binding and transport by a yeast StARkin domain

(2018) Julian-Alexander Jentsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites

(2018) Junsen Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transverse distribution of plasma membrane bilayer cholesterol: Picking sides

(2018) Theodore L. Steck et al.   TRAFFIC

GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells

(2018) Marina Besprozvannaya et al.   eLife

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

(2018) Jaspreet Sandhu et al.   CELL

Novel candidate genes and variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability

(2018) Regie Lyn P. Santos-Cortez et al.   HUMAN GENETICS

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2)

(2018) Huan Wang et al.   MOLECULAR CELL

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

(2018) Louise H. Wong et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

(2018) Jie Luo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Lipid exchange at ER-mitochondria contact sites: a puzzle falling into place with quite a few pieces missing

(2018) Carmelina Petrungaro et al.   CURRENT OPINION IN CELL BIOLOGY

Variability of cholesterol accessibility in human red blood cells measured using a bacterial cholesterol-binding toxin

(2017) Rima S Chakrabarti et al.   eLife

Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol

(2017) Rodney Elwood Infante et al.   eLife

Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders

(2017) Miriam S. Reuter et al.   JAMA Psychiatry

Control of plasma membrane lipid homeostasis by the extended synaptotagmins

(2016) Yasunori Saheki et al.   NATURE CELL BIOLOGY

Switch-like Responses of Two Cholesterol Sensors Do Not Require Protein Oligomerization in Membranes

(2015) Austin Gay et al.   BIOPHYSICAL JOURNAL

A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins

(2015) Joseph L. Goldstein et al.   CELL

Transbilayer Lipid Interactions Mediate Nanoclustering of Lipid-Anchored Proteins

(2015) Riya Raghupathy et al.   CELL

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol

(2015) M. Maekawa et al.   JOURNAL OF CELL SCIENCE

Structure and function of ER membrane contact sites with other organelles

(2015) Melissa J. Phillips et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1

(2015) Xiaoying Jian et al.   STRUCTURE

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Topological Regulation of Lipid Balance in Cells

(2014) Guillaume Drin   Annual Review of Biochemistry

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Essentially All Excess Fibroblast Cholesterol Moves from Plasma Membranes to Intracellular Compartments

(2014) Yvonne Lange et al.   PLoS One

Phospholipid Synthesis and Transport in Mammalian Cells

(2014) Jean E. Vance   TRAFFIC

Stability and Stoichiometry of Bilayer Phospholipid–Cholesterol Complexes: Relationship to Cellular Sterol Distribution and Homeostasis

(2013) Yvonne Lange et al.   BIOCHEMISTRY

Staying in touch: the molecular era of organelle contact sites

(2011) Yael Elbaz et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

Accessibility of Cholesterol in Endoplasmic Reticulum Membranes and Activation of SREBP-2 Switch Abruptly at a Common Cholesterol Threshold

(2010) Anna Sokolov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2

(2009) M. Guerrero-Valero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE