Mitochondrial translation deficiency impairs NAD + ‐mediated lysosomal acidification

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis

(2019) Lorena Fernandez-Mosquera et al.   Autophagy

Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects

(2019) Cláudia M. Deus et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NAD metabolism: Implications in aging and longevity

(2018) Keisuke Yaku et al.   AGEING RESEARCH REVIEWS

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance

(2018) Maryam Gulshan et al.   AGING CELL

Lysosomes Support the Degradation, Signaling, and Mitochondrial Metabolism Necessary for Human Epidermal Differentiation

(2018) Christine L. Monteleon et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

(2018) Antonio Davila et al.   eLife

Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice

(2018) Álvaro F. Fernández et al.   NATURE

A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers

(2018) Andrés Norambuena et al.   EMBO JOURNAL

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

(2017) Monther Abu-Remaileh et al.   SCIENCE

PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes

(2017) Christin Bissig et al.   TRAFFIC

NAD + in Aging: Molecular Mechanisms and Translational Implications

(2017) Evandro F. Fang et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders

(2017) Nicoletta Plotegher et al.   TRENDS IN MOLECULAR MEDICINE

Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis

(2017) Lorena Fernández-Mosquera et al.   Scientific Reports

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration

(2017) Mikako Yagi et al.   Scientific Reports

Loss of Mitochondrial Function Impairs Lysosomes

(2016) Julie Demers-Lamarche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies

(2016) Masakazu Kohda et al.   PLoS Genetics

Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo

(2016) Masashi Yamamoto et al.   PLoS One

Chaperone-like protein p32 regulates ULK1 stability and autophagy

(2015) H Jiao et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses

(2015) Francesc Baixauli et al.   Cell Metabolism

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

(2015) Carles Cantó et al.   Cell Metabolism

Mitochondrial Reactive Oxygen Species at the Heart of the Matter: New Therapeutic Approaches for Cardiovascular Diseases

(2015) O. S. Kornfeld et al.   CIRCULATION RESEARCH

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

(2015) Ju-Hyun Lee et al.   Cell Reports

Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy

(2014) Tania Zaglia et al.   JOURNAL OF CLINICAL INVESTIGATION

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

Regulation of Luminal Acidification by the V-ATPase

(2013) Sylvie Breton et al.   PHYSIOLOGY

Insight into Molecular and Functional Properties of NMNAT3 Reveals New Hints of NAD Homeostasis within Human Mitochondria

(2013) Roberta Felici et al.   PLoS One

NMNATs, evolutionarily conserved neuronal maintenance factors

(2013) Yousuf O. Ali et al.   TRENDS IN NEUROSCIENCES

p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability

(2012) Mikako Yagi et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy

(2011) Mantong Zhao et al.   Cell Metabolism

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Energetics and Therapeutics

(2010) Douglas C. Wallace et al.   Annual Review of Pathology-Mechanisms of Disease

The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging

(2010) Scott F. Leiser et al.   BIOLOGICAL CHEMISTRY

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Enrichment and analysis of secretory lysosomes from lymphocyte populations

(2009) Hendrik Schmidt et al.   BMC IMMUNOLOGY

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH