Phosphorothioate nucleic acids for probing metal binding, biosensing and nanotechnology

Crystal engineering with DNA

(2019) Christine R. Laramy et al.   Nature Reviews Materials

Discovery of and Insights into DNA “Codes” for Tunable Morphologies of Metal Nanoparticles

(2019) Nitya Sai Reddy Satyavolu et al.   Small

Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors

(2019) Kevin Hwang et al.   INORGANIC CHEMISTRY

Evidence for a Catalytic Strategy to Promote Nucleophile Activation in Metal-Dependent RNA-Cleaving Ribozymes and 8-17 DNAzyme

(2019) Abir Ganguly et al.   ACS Catalysis

Programming nanoparticle valence bonds with single-stranded DNA encoders

(2019) Guangbao Yao et al.   NATURE MATERIALS

A Half-Century History of Applications of Antisense Oligonucleotides in Medicine, Agriculture and Forestry: We Should Continue the Journey

(2018) Volodymyr Oberemok et al.   MOLECULES

Metal ion complexes of nucleoside phosphorothioates reflecting the ambivalent properties of lead(ii)

(2018) Astrid Sigel et al.   NEW JOURNAL OF CHEMISTRY

Simple construction of ratiometric fluorescent probe for the detection of dopamine and tyrosinase by the naked eye

(2018) Guobin Mao et al.   ANALYST

Phosphorothioated Oligonucleotides as Receptor Layers in Electrochemical Detection of Uranyl Cation

(2017) Agnieszka Bala et al.   JOURNAL OF THE ELECTROCHEMICAL SOCIETY

The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

(2017) Jamie L Bingaman et al.   Nature Chemical Biology

Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ

(2017) Xijun Piao et al.   RNA

Hg2+ detection using a phosphorothioate RNA probe adsorbed on graphene oxide and a comparison with thymine-rich DNA

(2016) Po-Jung Jimmy Huang et al.   ANALYST

One-pot synthesis of strongly fluorescent DNA-CuInS2 quantum dots for label-free and ultrasensitive detection of anthrax lethal factor DNA

(2016) Ziping Liu et al.   ANALYTICA CHIMICA ACTA

An Ultrasensitive Light-up Cu2+ Biosensor Using a New DNAzyme Cleaving a Phosphorothioate-Modified Substrate

(2016) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

Application of nucleic acid analogues as receptor layers for biosensors

(2016) Agnieszka Bala et al.   Analytical Methods

One-pot Synthesis of Quencher Labeled Hairpin DNA–CdTe QDs Conjugate for Target DNA and Deoxyribonuclease I Detection

(2016) Qingfeng ZHANG et al.   ANALYTICAL SCIENCES

In Vitro Selection of a DNAzyme Cooperatively Binding Two Lanthanide Ions for RNA Cleavage

(2016) Po-Jung Jimmy Huang et al.   BIOCHEMISTRY

Photocaged G-Quadruplex DNAzyme and Aptamer by Post-Synthetic Modification on Phosphodiester Backbone

(2016) Mengli Feng et al.   BIOCONJUGATE CHEMISTRY

Metal binding to nucleic acids – A journey from the beginning

(2016) Einar Sletten   INORGANICA CHIMICA ACTA

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

(2016) Kevin Hwang et al.   INORGANICA CHIMICA ACTA

Crystal structure of a DNA catalyst

(2016) Almudena Ponce-Salvatierra et al.   NATURE

Evoking picomolar binding in RNA by a single phosphorodithioate linkage

(2016) N. Dinuka Abeydeera et al.   NUCLEIC ACIDS RESEARCH

DNA-Mediated Morphological Control of Silver Nanoparticles

(2016) Jiuxing Li et al.   Small

Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes

(2016) Scott K. Silverman   TRENDS IN BIOCHEMICAL SCIENCES

Structural investigation into physiological DNA phosphorothioate modification

(2016) Wenxian Lan et al.   Scientific Reports

Postsynthetic Modification of DNA Phosphodiester Backbone for Photocaged DNAzyme

(2015) Xiaoyan Wang et al.   ACS Chemical Biology

Desulfurization Activated Phosphorothioate DNAzyme for the Detection of Thallium

(2015) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

Cleavable Molecular Beacon for Hg2+ Detection Based on Phosphorothioate RNA Modifications

(2015) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds

(2015) Tingjie Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical Characterization of a Lanthanide-Dependent DNAzyme with Normal and Phosphorothioate-Modified Substrates

(2015) Mahsa Vazin et al.   BIOCHEMISTRY

Inverse Thio Effects in the Hepatitis Delta Virus Ribozyme Reveal that the Reaction Pathway Is Controlled by Metal Ion Charge Density

(2015) Pallavi Thaplyal et al.   BIOCHEMISTRY

Mechanistic Insight into DNA-Guided Control of Nanoparticle Morphologies

(2015) Li Huey Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational evolution of Cd2+-specific DNAzymes with phosphorothioate modified cleavage junction and Cd2+sensing

(2015) Po-Jung Jimmy Huang et al.   NUCLEIC ACIDS RESEARCH

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Phosphorothioate DNA Stabilized Fluorescent Gold and Silver Nanoclusters

(2015) Daniel Weadick et al.   Nanomaterials

DNA as a Powerful Tool for Morphology Control, Spatial Positioning, and Dynamic Assembly of Nanoparticles

(2014) Li Huey Tan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy

(2014) Hao Liang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles

(2014) Wenhu Zhou et al.   ACS Applied Materials & Interfaces

Sensing Parts-per-Trillion Cd2+, Hg2+, and Pb2+ Collectively and Individually Using Phosphorothioate DNAzymes

(2014) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

DNA-Templated Assembly of a Heterobivalent Quantum Dot Nanoprobe For Extra- and Intracellular Dual-Targeting and Imaging of Live Cancer Cells

(2014) Wei Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thioaptamers targeting dengue virus type-2 envelope protein domain III

(2014) Sai Hari A. Gandham et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nucleic Acid Catalysis: Metals, Nucleobases, and Other Cofactors

(2014) W. Luke Ward et al.   CHEMICAL REVIEWS

DNA Sequence-Dependent Morphological Evolution of Silver Nanoparticles and Their Optical and Hybridization Properties

(2014) Jiangjiexing Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new heavy lanthanide-dependent DNAzyme displaying strong metal cooperativity and unrescuable phosphorothioate effect

(2014) Po-Jung Jimmy Huang et al.   NUCLEIC ACIDS RESEARCH

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

(2014) Sherry Y. Wu et al.   Nature Communications

Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

(2014) Fritz Eckstein   Nucleic Acid Therapeutics

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Thio Effects and an Unconventional Metal Ion Rescue in the Genomic Hepatitis Delta Virus Ribozyme

(2013) Pallavi Thaplyal et al.   BIOCHEMISTRY

Formation of targeted monovalent quantum dots by steric exclusion

(2013) Justin Farlow et al.   NATURE METHODS

Dissecting the effect of anions on Hg2+ detection using a FRET based DNA probe

(2012) Mehmet Murat Kiy et al.   ANALYST

Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

(2012) Glen F. Deleavey et al.   CHEMISTRY & BIOLOGY

Stereocontrolled Solid-Phase Synthesis of Phosphorothioate Oligoribonucleotides Using 2′-O-(2-Cyanoethoxymethyl)-nucleoside 3′-O-Oxazaphospholidine Monomers

(2012) Yohei Nukaga et al.   JOURNAL OF ORGANIC CHEMISTRY

Robust DNA-Functionalized Core/Shell Quantum Dots with Fluorescent Emission Spanning from UV–vis to Near-IR and Compatible with DNA-Directed Self-Assembly

(2012) Zhengtao Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adsorption of DNA onto gold nanoparticles and graphene oxide: surface science and applications

(2012) Juewen Liu   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

G4-DNA-Coated Gold Nanoparticles: Synthesis and Assembly

(2011) Irit Lubitz et al.   BIOCONJUGATE CHEMISTRY

Self-Assembled G4-DNA-Silver Nanoparticle Structures

(2011) Irit Lubitz et al.   BIOCONJUGATE CHEMISTRY

Nucleic acid X-ray crystallography via direct selenium derivatization

(2011) Lina Lin et al.   CHEMICAL SOCIETY REVIEWS

Binding of metal ions by pyrimidine base pairs in DNA duplexes

(2011) Akira Ono et al.   CHEMICAL SOCIETY REVIEWS

Phosphorothioate Nucleotides and Oligonucleotides - Recent Progress in Synthesis and Application

(2011) Piotr Guga et al.   CHEMISTRY & BIODIVERSITY

DNA-based programming of quantum dot valency, self-assembly and luminescence

(2011) Grigory Tikhomirov et al.   Nature Nanotechnology

Challenges and opportunities for structural DNA nanotechnology

(2011) Andre V. Pinheiro et al.   Nature Nanotechnology

Site-Specific Attachment of Proteins onto a 3D DNA Tetrahedron through Backbone-Modified Phosphorothioate DNA

(2011) Ngo Yin Wong et al.   Small

A Stability Concept for Metal Ion Coordination to Single-Stranded Nucleic Acids and Affinities of Individual Sites

(2010) Roland K. O. Sigel et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Stereochemical Glimpse of the Active Site of the 8−17 Deoxyribozyme from Iodine-Mediated Cross-Links Formed with the Substrate’s Scissile Site

(2010) Gurpreet S. Sekhon et al.   BIOCHEMISTRY

Controlled Alignment of Multiple Proteins and Nanoparticles with Nanometer Resolution via Backbone-Modified Phosphorothioate DNA and Bifunctional Linkers

(2010) Jung Heon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Twenty years hunting for sulfur in DNA

(2010) Shi Chen et al.   Protein & Cell

Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach

(2009) Xiaohong Fang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stable silver nanoparticle–DNA conjugates for directed self-assembly of core-satellite silver–gold nanoclusters

(2009) Suchetan Pal et al.   CHEMICAL COMMUNICATIONS

Biologically Inspired Synthetic Enzymes Made from DNA

(2009) Kenny Schlosser et al.   CHEMISTRY & BIOLOGY

Adenosine Reagentless Electrochemical Aptasensor Using a Phosphorothioate Immobilization Strategy

(2009) Helena Ceretti et al.   ELECTROANALYSIS

Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-β1 protein

(2008) Jonghoon Kang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discrimination in Metal-Ion Binding to RNA Dinucleotides with a Non-Bridging Oxygen or Sulfur in the Phosphate Diester Link

(2008) Bernd Knobloch et al.   CHEMISTRY-A EUROPEAN JOURNAL

Effect of RP and SPPhosphorothioate Substitution at the Scissile Site on the Cleavage Activity of Deoxyribozyme 10-23

(2008) Barbara Nawrot et al.   CURRENT ORGANIC CHEMISTRY

One-step DNA-programmed growth of luminescent and biofunctionalized nanocrystals

(2008) Nan Ma et al.   Nature Nanotechnology

Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme

(2008) K. Schlosser et al.   NUCLEIC ACIDS RESEARCH