The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ

(2019) Cecilia Hurtado et al.   Scientific Reports

Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis

(2019) Jan Broder Engler et al.   JOURNAL OF IMMUNOLOGY

DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch Signaling

(2019) Jie Feng et al.   Frontiers in Oncology

Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells

(2019) Melissa S. F. Ng et al.   Science Immunology

CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis

(2018) Alsya J. Affandi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation

(2018) Lei Ma et al.   Journal of Translational Medicine

Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival

(2018) Andrew Baker et al.   ONCOGENE

Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation

(2018) Tomohiro Fukaya et al.   Frontiers in Immunology

Elevated Notch1 enhances interleukin-22 production by CD4+ T cells via aryl hydrocarbon receptor in patients with lung adenocarcinoma

(2018) Bo Pang et al.   BIOSCIENCE REPORTS

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

(2018) Marc O. Johnson et al.   CELL

Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis

(2018) Yusuke Miyazaki et al.   Frontiers in Immunology

Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity

(2017) Maximilian W. Plank et al.   JOURNAL OF IMMUNOLOGY

Notch Signaling in Development, Tissue Homeostasis, and Disease

(2017) Chris Siebel et al.   PHYSIOLOGICAL REVIEWS

Notch Signaling Regulates Circulating T Helper 22 Cells in Patients with Chronic Hepatitis C

(2017) Ben-Chun Jiang et al.   VIRAL IMMUNOLOGY

Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea

(2017) Qianqian Chen et al.   Stem Cell Reports

Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus

(2016) Xiaojing Li et al.   Cell Death & Disease

Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis

(2015) Chong Zeng et al.   APOPTOSIS

IL-21 induces IL-22 production in CD4+ T cells

(2014) Ada Yeste et al.   Nature Communications

Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells

(2013) Tatsuro Murano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation

(2013) Elodie Segura et al.   IMMUNITY

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria

(2012) Rajatava Basu et al.   IMMUNITY

SPARC Stimulates Neuronal Differentiation of Medulloblastoma Cells via the Notch1/STAT3 Pathway

(2011) P. Bhoopathi et al.   CANCER RESEARCH

Notch Signaling Regulates Mouse and Human Th17 Differentiation

(2011) S. Keerthivasan et al.   JOURNAL OF IMMUNOLOGY

Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention

(2011) Ning Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor

(2010) M. S. Alam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY