CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis

CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells

(2017) Sandra C. Silva-Cardoso et al.   JOURNAL OF IMMUNOLOGY

Psoriatic Arthritis

(2017) Christopher T. Ritchlin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

(2016) G. Guggino et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL-23/IL-17 axis in spondyloarthritis-bench to bedside

(2016) Siba P. Raychaudhuri et al.   CLINICAL RHEUMATOLOGY

Serum CXCL4 increase in primary Sjögren’s syndrome characterizes patients with microvascular involvement and reduced salivary gland infiltration and lymph node involvement

(2016) Serena Vettori et al.   CLINICAL RHEUMATOLOGY

CXCL4 and CXCL4L1 Differentially Affect Monocyte Survival and Dendritic Cell Differentiation and Phagocytosis

(2016) Mieke Gouwy et al.   PLoS One

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis

(2015) L Yeo et al.   ANNALS OF THE RHEUMATIC DISEASES

Platelets Play Differential Role During the Initiation and Progression of Autoimmune NeuroinflammationNovelty and Significance

(2015) Sarah C. Starossom et al.   CIRCULATION RESEARCH

Regulation of human helper T cell subset differentiation by cytokines

(2015) Nathalie Schmitt et al.   CURRENT OPINION IN IMMUNOLOGY

Elevated expression of platelet-derived chemokines in patients with antiphospholipid syndrome

(2015) Markos D. Patsouras et al.   JOURNAL OF AUTOIMMUNITY

The IL-23–IL-17 axis in inflammatory arthritis

(2015) Erik Lubberts   Nature Reviews Rheumatology

Brief Report: Enrichment of Activated Group 3 Innate Lymphoid Cells in Psoriatic Arthritis Synovial Fluid

(2015) Emmerik F. A. Leijten et al.   Arthritis & Rheumatology

Pathogenesis of Systemic Sclerosis

(2015) Debendra Pattanaik et al.   Frontiers in Immunology

Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus

(2015) Nils Rother et al.   Frontiers in Immunology

IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis

(2014) Iannis E Adamopoulos et al.   ANNALS OF THE RHEUMATIC DISEASES

Platelet Factor 4 Inhibits IL-17/Stat3 Pathway via Upregulation of SOCS3 Expression in Melanoma

(2014) Shanshan Fang et al.   INFLAMMATION

Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection

(2014) Guanfang Shi et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of IL-17+ T Cell Trafficking and Development by IFN- : Mechanism and Pathological Relevance in Psoriasis

(2014) I. Kryczek et al.   JOURNAL OF IMMUNOLOGY

Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+T-cell proliferation

(2014) L. Zhu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells

(2014) R. Noster et al.   Science Translational Medicine

Interleukin-17+CD8+ T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

(2014) Bina Menon et al.   Arthritis & Rheumatology

Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis

(2013) Lenny van Bon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

(2013) T. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet chemokines in health and disease

(2013) Ela Karshovska et al.   THROMBOSIS AND HAEMOSTASIS

Intra-articular CD1c-expressing myeloid dendritic cells from rheumatoid arthritis patients express a unique set of T cell-attracting chemokines and spontaneously induce Th1, Th17 and Th2 cell activity

(2013) Frederique M Moret et al.   ARTHRITIS RESEARCH & THERAPY

Th17 and Th22 cells in psoriatic arthritis and psoriasis

(2013) Helen Benham et al.   ARTHRITIS RESEARCH & THERAPY

Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury

(2012) Jochen Grommes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Role of Platelet Factor 4 in Local and Remote Tissue Damage in a Mouse Model of Mesenteric Ischemia/Reperfusion Injury

(2012) Peter H. Lapchak et al.   PLoS One

Molecular pathways of platelet factor 4/CXCL4 signaling

(2011) Brigitte Kasper et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

IL-17 receptor and its functional significance in psoriatic arthritis

(2011) Siba P. Raychaudhuri et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans

(2011) Norbert Gerdes et al.   THROMBOSIS AND HAEMOSTASIS

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease

(2011) Marie-Elise Truchetet et al.   ARTHRITIS RESEARCH & THERAPY

CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1

(2010) Brigitte Kasper et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Th17 cells: Are they different from murine Th17 cells?

(2009) Francesco Annunziato et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

(2009) Rory R Koenen et al.   NATURE MEDICINE

Elevated Platelet Activation in Patients with Atopic Dermatitis and Psoriasis: Increased Plasma Levels of β-Thromboglobulin and Platelet Factor 4

(2008) Risa Tamagawa-Mineoka et al.   ALLERGOLOGY INTERNATIONAL