Discovery of degradable niclosamide derivatives able to specially inhibit small cell lung cancer (SCLC)

Niclosamide, a Drug with Many (Re)purposes

(2018) Hachemi Kadri et al.   ChemMedChem

Octenylsuccinate hydroxypropyl phytoglycogen enhances the solubility and in-vitro antitumor efficacy of niclosamide

(2018) Ying Xie et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide

(2018) Lu Lu et al.   ONCOGENE

A scalable online tool for quantitative social network assessment reveals potentially modifiable social environmental risks

(2018) Amar Dhand et al.   Nature Communications

Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer

(2017) Chengfei Liu et al.   MOLECULAR CANCER THERAPEUTICS

Precision Diagnosis and Treatment for Advanced Non–Small-Cell Lung Cancer

(2017) Martin Reck et al.   NEW ENGLAND JOURNAL OF MEDICINE

New Triazole-Containing Branched Bis(dipeptidomimetic) – Switching from Self-Dimerization to Anion-Binding Properties

(2017) Hak-Fun Chow et al.   SYNLETT

Lung Cancer-Targeting Peptides with Multi-subtype Indication for Combinational Drug Delivery and Molecular Imaging

(2017) Yi-Hsuan Chi et al.   Theranostics

A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities

(2016) Youlin Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Anthelmintic Niclosamide Disrupts the Interplay of p65 and FOXM1/β-catenin and Eradicates Leukemia Stem Cells in Chronic Myelogenous Leukemia

(2016) Bei Jin et al.   CLINICAL CANCER RESEARCH

Submillisecond organic synthesis: Outpacing Fries rearrangement through microfluidic rapid mixing

(2016) H. Kim et al.   SCIENCE

Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer

(2016) Junjun Liu et al.   TUMOR BIOLOGY

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

(2016) Rebecca C. Arend et al.   Oncotarget

Structure–activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure

(2015) Robert A. Mook et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthetic strategies to achieve further-functionalised monoaryl phosphate primary building units: crystal structures and solid-state aggregation behavior

(2015) Aijaz A. Dar et al.   NEW JOURNAL OF CHEMISTRY

Direct biosynthetic cyclization of a distorted paracyclophane highlighted by double isotopic labelling of l-tyrosine

(2015) Alexandre Ear et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design and evaluation of injectable niclosamide nanocrystals prepared by wet media milling technique

(2014) Yanghuan Ye et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Effect of Niclosamide on Basal-like Breast Cancers

(2014) A. I. Londono-Joshi et al.   MOLECULAR CANCER THERAPEUTICS

Understanding and targeting cancer stem cells: therapeutic implications and challenges

(2013) Ke Chen et al.   ACTA PHARMACOLOGICA SINICA

A phase I clinical trial of weekly oral topotecan for relapsed small cell lung cancer

(2013) S. Agelaki et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Anticancer Effects of Niclosamide in Human Glioblastoma

(2013) A. Wieland et al.   CLINICAL CANCER RESEARCH

Niclosamide Overcomes Acquired Resistance to Erlotinib through Suppression of STAT3 in Non-Small Cell Lung Cancer

(2013) R. Li et al.   MOLECULAR CANCER THERAPEUTICS

Disruption of STAT3 by Niclosamide Reverses Radioresistance of Human Lung Cancer

(2013) S. You et al.   MOLECULAR CANCER THERAPEUTICS

Discovery of O-Alkylamino-Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents

(2013) Haijun Chen et al.   ACS Medicinal Chemistry Letters

Pharmaceutical Cocrystals of Niclosamide

(2012) Palash Sanphui et al.   CRYSTAL GROWTH & DESIGN

Salicylanilide Inhibitors of Toxoplasma gondii

(2012) Alina Fomovska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of glycosylated psoralen derivatives

(2012) Chao-Yue Chen et al.   TETRAHEDRON

Quality control and fate determination of Hsp90 client proteins

(2011) Maria A. Theodoraki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phase Solubility Studies of Poorly Soluble Drug Molecules by Using O-Phosphorylated Calixarenes as Drug-Solubilizing Agents

(2011) Mevlüt Bayrakcı et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Novel Effect of Antihelminthic Niclosamide on S100A4-Mediated Metastatic Progression in Colon Cancer

(2011) U. Sack et al.   JNCI-Journal of the National Cancer Institute

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species

(2010) Y. Jin et al.   CANCER RESEARCH

Semi-synthesis and anti-tumor activity of 5,8-O-dimethyl acylshikonin derivatives

(2010) Wen Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure−Activity Relationship Analysis of Novel Derivatives of Narciclasine (anAmaryllidaceaeIsocarbostyril Derivative) as Potential Anticancer Agents

(2009) Laurent Ingrassia et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Advances in the Second-Line Treatment of Small Cell Lung Cancer

(2009) J. L. Hurwitz et al.   ONCOLOGIST