Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer

Epithelial–mesenchymal transition induces similar metabolic alterations in two independent breast cancer cell lines

(2015) Yuvabharath Kondaveeti et al.   CANCER LETTERS

The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro

(2015) Olga Piskareva et al.   CANCER LETTERS

The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells

(2015) Ryan Charles Pink et al.   GYNECOLOGIC ONCOLOGY

Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction

(2015) D-W Wu et al.   ONCOGENE

Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance

(2014) Le Yu et al.   CANCER LETTERS

Circulating tumor cells exhibit a biologically aggressive cancer phenotype accompanied by selective resistance to chemotherapy

(2014) Janet M. Pavese et al.   CANCER LETTERS

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

(2014) Yonghe Li et al.   CANCER LETTERS

ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway

(2014) Marco Lo Iacono et al.   INTERNATIONAL JOURNAL OF CANCER

Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial

(2014) Gunter von Minckwitz et al.   LANCET ONCOLOGY

Effect of Niclosamide on Basal-like Breast Cancers

(2014) A. I. Londono-Joshi et al.   MOLECULAR CANCER THERAPEUTICS

Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment

(2014) D Ciavardelli et al.   Cell Death & Disease

HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2

(2013) G. Cheng et al.   CANCER RESEARCH

Dual Inhibition of PI3K and mTOR Mitigates Compensatory AKT Activation and Improves Tamoxifen Response in Breast Cancer

(2013) Xiaosong Chen et al.   MOLECULAR CANCER RESEARCH

The Invasion Inhibitor Sarasinoside A1 Reverses Mesenchymal Tumor Transformation in an E-Cadherin–Independent Manner

(2013) Pamela Austin et al.   MOLECULAR CANCER RESEARCH

Niclosamide Overcomes Acquired Resistance to Erlotinib through Suppression of STAT3 in Non-Small Cell Lung Cancer

(2013) R. Li et al.   MOLECULAR CANCER THERAPEUTICS

Drug Screening Identifies Niclosamide as an Inhibitor of Breast Cancer Stem-Like Cells

(2013) Yu-Chi Wang et al.   PLoS One

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

(2012) Alexandria M Haslehurst et al.   BMC CANCER

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Expression of Wnt3 Activates Wnt/ -Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells

(2012) Y. Wu et al.   MOLECULAR CANCER RESEARCH

Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide

(2012) Y.-T. Yo et al.   MOLECULAR CANCER THERAPEUTICS

Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death

(2011) So-Jung Park et al.   BMB Reports

Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations

(2011) T. Osada et al.   CANCER RESEARCH

Cancer early dissemination: cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor   signalling

(2011) H. Sabe   JOURNAL OF BIOCHEMISTRY

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

(2011) Wenyan Lu et al.   PLoS One

Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

(2011) F L Khanim et al.   Blood Cancer Journal

Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression pattern

(2010) Özlem Darcansoy Işeri et al.   BIOMEDICINE & PHARMACOTHERAPY

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species

(2010) Y. Jin et al.   CANCER RESEARCH

Pharmacogenomics of Taxane/Platinum Therapy in Ovarian Cancer

(2010) Sharon Marsh   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

(2010) Daniel P. Silver et al.   JOURNAL OF CLINICAL ONCOLOGY

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells

(2009) M. Santisteban et al.   CANCER RESEARCH

Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells

(2009) Mi Ra Kim et al.   CANCER SCIENCE

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells

(2009) An-Ming Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies

(2009) Brett G. Hollier et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells

(2009) Martin Michaelis et al.   Molecular Cancer

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

(2009) Nawneet K. Kurrey et al.   STEM CELLS

In vitro trypanocidal activity of the anti-helminthic drug niclosamide

(2008) Karin Merschjohann et al.   EXPERIMENTAL PARASITOLOGY