Comprehensive analysis of host cell impurities in monoclonal antibodies with improved sensitivity by capillary zone electrophoresis mass spectrometry

Quantitative analysis of the supernatant from host and transfected CHO cells using iTRAQ 8-plex technique

(2016) Guijie Zhu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Capillary zone electrophoresis tandem mass spectrometry detects low concentration host cell impurities in monoclonal antibodies

(2016) Guijie Zhu et al.   ELECTROPHORESIS

Detachable Strong Cation Exchange Monolith, Integrated with Capillary Zone Electrophoresis and Coupled with pH Gradient Elution, Produces Improved Sensitivity and Numbers of Peptide Identifications during Bottom-up Analysis of Complex Proteomes

(2015) Zhenbin Zhang et al.   ANALYTICAL CHEMISTRY

Integrated strong cation-exchange hybrid monolith coupled with capillary zone electrophoresis and simultaneous dynamic pH junction for large-volume proteomic analysis by mass spectrometry

(2015) Zhenbin Zhang et al.   TALANTA

Absolute quantitation of host cell proteins in recombinant human monoclonal antibodies with an automated CZE-ESI-MS/MS system

(2014) Guijie Zhu et al.   ELECTROPHORESIS

Comprehensive tracking of host cell proteins during monoclonal antibody purifications using mass spectrometry

(2014) Qingchun Zhang et al.   mAbs

Proteomic Analysis of Chinese Hamster Ovary Cells

(2012) Deniz Baycin-Hizal et al.   JOURNAL OF PROTEOME RESEARCH

CE–MS for proteomics: Advances in interface development and application

(2012) Rawi Ramautar et al.   Journal of Proteomics

Analysis of host-cell proteins in biotherapeutic proteins by comprehensive online two-dimensional liquid chromatography/mass spectrometry

(2012) Catalin Doneanu et al.   mAbs

A rapid cIEF–ESI–MS/MS method for host cell protein analysis of a recombinant human monoclonal antibody

(2012) Guijie Zhu et al.   TALANTA

Online Comprehensive RPLC × RPLC with Mass Spectrometry Detection for the Analysis of Proteome Samples

(2011) Paola Donato et al.   ANALYTICAL CHEMISTRY

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

Engineering mammalian cells in bioprocessing – current achievements and future perspectives

(2010) Yiping Lim et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activity

(2010) Sharon X. Gao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Simplified capillary electrophoresis nanospray sheath-flow interface for high efficiency and sensitive peptide analysis

(2010) Roza Wojcik et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Assessment of cell engineering strategies for improved therapeutic protein production in CHO cells

(2008) Chaya Mohan et al.   Biotechnology Journal

Limitations to the comparative proteomic analysis of thrombopoietin producing Chinese hamster ovary cells treated with sodium butyrate

(2007) Jong Youn Baik et al.   JOURNAL OF BIOTECHNOLOGY