Capillary zone electrophoresis tandem mass spectrometry detects low concentration host cell impurities in monoclonal antibodies

Thermally-initiated free radical polymerization for reproducible production of stable linear polyacrylamide coated capillaries, and their application to proteomic analysis using capillary zone electrophoresis–mass spectrometry

(2016) Guijie Zhu et al.   TALANTA

Detachable Strong Cation Exchange Monolith, Integrated with Capillary Zone Electrophoresis and Coupled with pH Gradient Elution, Produces Improved Sensitivity and Numbers of Peptide Identifications during Bottom-up Analysis of Complex Proteomes

(2015) Zhenbin Zhang et al.   ANALYTICAL CHEMISTRY

Third-Generation Electrokinetically Pumped Sheath-Flow Nanospray Interface with Improved Stability and Sensitivity for Automated Capillary Zone Electrophoresis–Mass Spectrometry Analysis of Complex Proteome Digests

(2015) Liangliang Sun et al.   JOURNAL OF PROTEOME RESEARCH

Integrated strong cation-exchange hybrid monolith coupled with capillary zone electrophoresis and simultaneous dynamic pH junction for large-volume proteomic analysis by mass spectrometry

(2015) Zhenbin Zhang et al.   TALANTA

Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry for Top-Down Characterization of Pyrococcus furiosus Proteins on a Proteome Scale

(2014) Xuemei Han et al.   ANALYTICAL CHEMISTRY

Simple Capillary Electrophoresis–Mass Spectrometry Method for Complex Glycan Analysis Using a Flow-Through Microvial Interface

(2014) Roxana G. Jayo et al.   ANALYTICAL CHEMISTRY

Bottom-Up Proteomics of Escherichia coli Using Dynamic pH Junction Preconcentration and Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry

(2014) Guijie Zhu et al.   ANALYTICAL CHEMISTRY

Over 10 000 Peptide Identifications from the HeLa Proteome by Using Single-Shot Capillary Zone Electrophoresis Combined with Tandem Mass Spectrometry

(2014) Liangliang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies

(2014) Nabila Aboulaich et al.   BIOTECHNOLOGY PROGRESS

Absolute quantitation of host cell proteins in recombinant human monoclonal antibodies with an automated CZE-ESI-MS/MS system

(2014) Guijie Zhu et al.   ELECTROPHORESIS

Uncovering immobilized trypsin digestion features from large-scale proteome data generated by high-resolution mass spectrometry

(2014) Liangliang Sun et al.   JOURNAL OF CHROMATOGRAPHY A

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs

(2014) Arne H. Smits et al.   NUCLEIC ACIDS RESEARCH

Single-Shot Proteomics Using Capillary Zone Electrophoresis–Electrospray Ionization-Tandem Mass Spectrometry with Production of More than 1 250 Escherichia coli Peptide Identifications in a 50 min Separation

(2013) Guijie Zhu et al.   ANALYTICAL CHEMISTRY

Capillary Isotachophoresis-Nanoelectrospray Ionization-Selected Reaction Monitoring MS via a Novel Sheathless Interface for High Sensitivity Sample Quantification

(2013) Chenchen Wang et al.   ANALYTICAL CHEMISTRY

Ultrasensitive and Fast Bottom-up Analysis of Femtogram Amounts of Complex Proteome Digests

(2013) Liangliang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Profiling the effects of process changes on residual host cell proteins in biotherapeutics by mass spectrometry

(2013) Matthew R. Schenauer et al.   BIOTECHNOLOGY PROGRESS

Capillary electrophoresis-mass spectrometry using a flow-through microvial interface for cationic metabolome analysis

(2013) Petrus W. Lindenburg et al.   ELECTROPHORESIS

Bottom-up proteome analysis ofE. coliusing capillary zone electrophoresis-tandem mass spectrometry with an electrokinetic sheath-flow electrospray interface

(2013) Xiaojing Yan et al.   PROTEOMICS

Identification and quantification of host cell protein impurities in biotherapeutics using mass spectrometry

(2012) Matthew R. Schenauer et al.   ANALYTICAL BIOCHEMISTRY

Improving the Comprehensiveness and Sensitivity of Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry for Proteomic Analysis

(2012) Yueju Wang et al.   ANALYTICAL CHEMISTRY

Analysis of host-cell proteins in biotherapeutic proteins by comprehensive online two-dimensional liquid chromatography/mass spectrometry

(2012) Catalin Doneanu et al.   mAbs

A rapid cIEF–ESI–MS/MS method for host cell protein analysis of a recombinant human monoclonal antibody

(2012) Guijie Zhu et al.   TALANTA

Optimization and Evaluation of a Sheathless Capillary Electrophoresis–Electrospray Ionization Mass Spectrometry Platform for Peptide Analysis: Comparison to Liquid Chromatography–Electrospray Ionization Mass Spectrometry

(2011) Klaus Faserl et al.   ANALYTICAL CHEMISTRY

Flow-Through Microvial Facilitating Interface of Capillary Isoelectric Focusing and Electrospray Ionization Mass Spectrometry

(2011) Xuefei Zhong et al.   ANALYTICAL CHEMISTRY

Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry as an Alternative Proteomics Platform to Ultraperformance Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry for Samples of Intermediate Complexity

(2011) Yihan Li et al.   ANALYTICAL CHEMISTRY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Decoupling CE and ESI for a more robust interface with MS

(2010) E. Jane Maxwell et al.   ELECTROPHORESIS

Simplified capillary electrophoresis nanospray sheath-flow interface for high efficiency and sensitive peptide analysis

(2010) Roza Wojcik et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Host cell proteins in biologics development: Identification, quantitation and risk assessment

(2009) Xing Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans

(2009) Johan Malmström et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY