Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.

Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures

(2020) Yixuan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

(2020) Giada Mondanelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia

(2020) Martina Ulivieri et al.   SCHIZOPHRENIA BULLETIN

COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

(2020) Tiffany Thomas et al.   JCI Insight

Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

(2020) Torben Kimhofer et al.   JOURNAL OF PROTEOME RESEARCH

Aryl Hydrocarbon Receptor Role in Co-Ordinating SARS-CoV-2 Entry and Symptomatology: Linking Cytotoxicity Changes in COVID-19 and Cancers; Modulation by Racial Discrimination Stress

(2020) George Anderson et al.   Biology-Basel

Assessment of neopterin and indoleamine 2,3‐dioxygenase activity in patients with seasonal influenza: A pilot study

(2019) Alex Pizzini et al.   Influenza and Other Respiratory Viruses

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

(2019) Rani K. Powers et al.   Nature Communications

Neopterin levels and Kyn/Trp ratios were significantly increased in dengue virus patients and subsequently decreased after recovery

(2019) Simon Geisler et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

(2017) Giada Mondanelli et al.   IMMUNITY

HIV/Human herpesvirus co-infections: Impact on tryptophan-kynurenine pathway and immune reconstitution

(2017) Siew Hwei Yap et al.   PLoS One

Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

(2016) Wejdan A. Aldajani et al.   Oncotarget

Indoleamine 2,3-dioxygenase downregulates T-cell receptor complex ζ-chain and c-Myc, and reduces proliferation, lactate dehydrogenase levels and mitochondrial glutaminase in human T-cells

(2015) THEODOROS ELEFTHERIADIS et al.   Molecular Medicine Reports

Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia

(2015) Francesco Fazio et al.   Scientific Reports

The Coevolution of IDO1 and AhR in the Emergence of Regulatory T-Cells in Mammals

(2015) Ursula Grohmann et al.   Frontiers in Immunology

Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice

(2014) Francesco Fazio et al.   NEUROPHARMACOLOGY

Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells

(2013) J. Loebbermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-Like Receptor-3 Ligation-Induced Indoleamine 2, 3-Dioxygenase Expression in Human Trophoblasts

(2011) Bo Wang et al.   ENDOCRINOLOGY

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

(2011) Patricia A Zunszain et al.   NEUROPSYCHOPHARMACOLOGY

Analysis of tryptophan catabolism in HBV patients by HPLC with programmed wavelength ultraviolet detection

(2009) Li Ma et al.   CLINICA CHIMICA ACTA