The emerging roles of OSBP-related proteins in cancer: Impacts through phosphoinositide metabolism and protein–protein interactions
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The emerging roles of OSBP-related proteins in cancer: Impacts through phosphoinositide metabolism and protein–protein interactions
Authors
Keywords
Cancer, Cell signaling, Lipid transport, ORP, OSBPL, Oxysterol-binding protein
Journal
BIOCHEMICAL PHARMACOLOGY
Volume -, Issue -, Pages 114455
Publisher
Elsevier BV
Online
2021-02-06
DOI
10.1016/j.bcp.2021.114455
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at PM-ER contact sites
- (2020) Gergő Gulyás et al. JOURNAL OF CELL SCIENCE
- OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis
- (2020) Mengyang Xu et al. JOURNAL OF IMMUNOLOGY
- To construct a ceRNA regulatory network as prognostic biomarkers for bladder cancer
- (2020) Jiazhi Jiang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes
- (2020) Kexin Zhao et al. MOLECULAR BIOLOGY OF THE CELL
- Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex
- (2020) Ryan S D'Souza et al. eLife
- FOXA1-induced circOSBPL10 potentiates cervical cancer cell proliferation and migration through miR-1179/UBE2Q1 axis
- (2020) Shanshan Yang et al. Cancer Cell International
- Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine
- (2020) Michael N. Trinh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway
- (2020) Hong-li Jiao et al. Cell Death & Disease
- GPCR mediated control of calcium dynamics: A systems perspective
- (2020) Vaibhav Dhyani et al. CELLULAR SIGNALLING
- Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer
- (2020) Pengfei Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer
- (2020) Mariah P. Csolle et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Lipid Metabolic Landscape of Cancers and New Therapeutic Perspectives
- (2020) Wenjun Wang et al. Frontiers in Oncology
- Cancer cell metabolism: Rewiring the mitochondrial hub
- (2020) Gabriela L. Oliveira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Molecular determinants of ER–Golgi contacts identified through a new FRET–FLIM system
- (2019) Rossella Venditti et al. JOURNAL OF CELL BIOLOGY
- ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells
- (2019) Wenbin Zhong et al. Cell Reports
- Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2
- (2019) Jiangqing Dong et al. Nature Communications
- Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer
- (2019) Sen Wang et al. ONCOGENE
- Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor
- (2019) Sospeter N. Njeru et al. ONCOGENE
- ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release
- (2019) Xiuye Cao et al. FASEB JOURNAL
- Mechanisms and regulation of cholesterol homeostasis
- (2019) Jie Luo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bridging the molecular and biological functions of the oxysterol-binding protein family
- (2018) Antonietta Pietrangelo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism
- (2018) Henriikka Kentala et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons
- (2018) Shinya Mochizuki et al. EXPERIMENTAL CELL RESEARCH
- Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation
- (2018) Henriikka Kentala et al. FASEB JOURNAL
- Oxysterol-binding protein–related protein 5 (ORP5) promotes cell proliferation by activation of mTORC1 signaling
- (2018) Ximing Du et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PI(4,5)P2controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites
- (2018) Mira Sohn et al. JOURNAL OF CELL BIOLOGY
- TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis
- (2018) Akito Dobashi et al. Oncotarget
- OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells
- (2018) Guoping Pan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 25-hydroxycholesterol down-regulates oxysterol binding protein like 2 (OSBPL2) via the p53/SREBF2/NFYA signaling pathway
- (2018) Quan Wang et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2)
- (2018) Huan Wang et al. MOLECULAR CELL
- ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol
- (2018) Annika Koponen et al. BIOCHIMIE
- Oxysterol-Binding Protein-Related Protein 8 Inhibits Gastric Cancer Growth Through Induction of ER Stress, Inhibition of Wnt Signaling, and Activation of Apoptosis
- (2017) Xiaohe Guo et al. ONCOLOGY RESEARCH
- ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane
- (2017) Rajesh Ghai et al. Nature Communications
- Targeted next generation sequencing identifies somatic mutations and gene fusions in papillary thyroid carcinoma
- (2017) Zheming Lu et al. Oncotarget
- Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System
- (2017) Kexin Zhao et al. Cell Reports
- miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and EffluxSignificance
- (2016) Mireille Ouimet et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A 19-Gene expression signature as a predictor of survival in colorectal cancer
- (2016) Nurul Ainin Abdul Aziz et al. BMC Medical Genomics
- Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
- (2016) L. Erdem-Eraslan et al. CANCER RESEARCH
- LDL–cholesterol transport to the endoplasmic reticulum
- (2016) Simon G. Pfisterer et al. CURRENT OPINION IN LIPIDOLOGY
- Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport
- (2016) Emily R. Eden et al. DEVELOPMENTAL CELL
- ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function
- (2016) Romain Galmes et al. EMBO REPORTS
- SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells
- (2016) William's Elong Edimo et al. JOURNAL OF CELL SCIENCE
- ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival
- (2016) Wenbin Zhong et al. Nature Communications
- Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca2+ homeostasis in cervical carcinoma cell lines
- (2016) Ji-Wei Li et al. Oncotarget
- The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis
- (2015) Lisa M. Ooms et al. CANCER CELL
- OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity
- (2015) Marion Weber-Boyvat et al. EXPERIMENTAL CELL RESEARCH
- Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors
- (2015) KAZUYA NAGANO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Oxysterol-binding Protein-related Protein 8 (ORP8) Increases Sensitivity of Hepatocellular Carcinoma Cells to Fas-Mediated Apoptosis
- (2015) Wenbin Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt
- (2015) Yan Ye et al. JOURNAL OF GASTROENTEROLOGY
- Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate
- (2015) J. Moser von Filseck et al. SCIENCE
- PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts
- (2015) J. Chung et al. SCIENCE
- PI3K/AKT signaling pathway and cancer: an updated review
- (2014) Miriam Martini et al. ANNALS OF MEDICINE
- Crosstalk between ERK, AKT, and cell survival
- (2014) Paul Dent CANCER BIOLOGY & THERAPY
- Oxysterol-binding Protein (OSBP)-related Protein 4 (ORP4) Is Essential for Cell Proliferation and Survival
- (2014) Mark Charman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis
- (2014) O. Keinan et al. JOURNAL OF CELL SCIENCE
- A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP
- (2013) Bruno Mesmin et al. CELL
- Cell survival and metastasis regulation by Akt signaling in colorectal cancer
- (2013) Ekta Agarwal et al. CELLULAR SIGNALLING
- Role of adhesion receptor trafficking in 3D cell migration
- (2013) Guillaume Jacquemet et al. CURRENT OPINION IN CELL BIOLOGY
- Oligo-astheno-teratozoospermia in mice lacking ORP4, a sterol-binding protein in the OSBP-related protein family
- (2013) Osamu Udagawa et al. GENES TO CELLS
- Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L
- (2013) R. van der Kant et al. JOURNAL OF CELL SCIENCE
- R-RAS2 overexpression in tumors of the human central nervous system
- (2013) Sylvia Gutierrez-Erlandsson et al. Molecular Cancer
- Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins
- (2013) Kenji Maeda et al. NATURE
- Structure of Osh3 Reveals a Conserved Mode of Phosphoinositide Binding in Oxysterol-Binding Proteins
- (2013) Junsen Tong et al. STRUCTURE
- Effective Killing of Leukemia Cells by the Natural Product OSW-1 through Disruption of Cellular Calcium Homeostasis
- (2012) Celia Garcia-Prieto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis
- (2012) Asako Goto et al. MOLECULAR BIOLOGY OF THE CELL
- The neural guidance receptor Plexin C1 delays melanoma progression
- (2012) Y Chen et al. ONCOGENE
- Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis
- (2011) Kasper Thorsen et al. BMC GENOMICS
- Phosphatidylserine is a critical modulator for Akt activation
- (2011) Bill X. Huang et al. JOURNAL OF CELL BIOLOGY
- A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
- (2011) Ximing Du et al. JOURNAL OF CELL BIOLOGY
- Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
- (2011) Maud de Saint-Jean et al. JOURNAL OF CELL BIOLOGY
- Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
- (2011) Sabine D. Jordan et al. NATURE CELL BIOLOGY
- Natural products reveal cancer cell dependence on oxysterol-binding proteins
- (2011) Anthony W G Burgett et al. Nature Chemical Biology
- Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: A potential molecular marker for tumor metastasis
- (2011) Watcharin Loilome et al. PARASITOLOGY INTERNATIONAL
- OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi–late endosome interface
- (2010) You Zhou et al. EXPERIMENTAL CELL RESEARCH
- R-Ras Regulates Migration through an Interaction with Filamin A in Melanoma Cells
- (2010) Joanna E. Gawecka et al. PLoS One
- The role of oxysterol binding protein-related protein 5 in pancreatic cancer
- (2009) Shinji Ishikawa et al. CANCER SCIENCE
- Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning
- (2009) Nuno Rocha et al. JOURNAL OF CELL BIOLOGY
- Oxysterol Binding Protein–related Protein 9 (ORP9) Is a Cholesterol Transfer Protein That Regulates Golgi Structure and Function
- (2009) Mike Ngo et al. MOLECULAR BIOLOGY OF THE CELL
- Oxysterol binding protein-related protein-5 is related to invasion and poor prognosis in pancreatic cancer
- (2008) Yoshikatsu Koga et al. CANCER SCIENCE
- The R-Ras interaction partner ORP3 regulates cell adhesion
- (2008) M. Lehto et al. JOURNAL OF CELL SCIENCE
- High Expression of Obesity-Linked Phosphatase SHIP2 in Invasive Breast Cancer Correlates with Reduced Disease-Free Survival
- (2008) Nagendra K. Prasad et al. TUMOR BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started