Metformin-conjugated micellar system with intratumoral pH responsive de-shielding for co-delivery of doxorubicin and nucleic acid

Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

(2020) Maximilian M. L. Knott et al.   CANCER AND METASTASIS REVIEWS

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

(2020) Esther Rheinbay et al.   NATURE

Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs

(2020) John Kokkinos et al.   BIOMATERIALS

Dual MicroRNA-Triggered Drug Release System for Combined Chemotherapy and Gene Therapy with Logic Operation

(2020) Renye Yue et al.   ACS Applied Materials & Interfaces

Dual Functional Immunostimulatory Polymeric Prodrug Carrier with Pendent Indoximod for Enhanced Cancer Immunochemotherapy

(2019) Zhuoya Wan et al.   Acta Biomaterialia

Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis

(2019) Jieni Xu et al.   BIOMATERIALS

pH-sensitive carboxymethyl chitosan hydrogels via acid-labile ortho ester linkage as an implantable drug delivery system

(2019) Jialu Gao et al.   CARBOHYDRATE POLYMERS

pH-responsive prodrug nanoparticles based on xylan-curcumin conjugate for the efficient delivery of curcumin in cancer therapy

(2018) Sauraj et al.   CARBOHYDRATE POLYMERS

PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy

(2018) Gizem Osman et al.   JOURNAL OF CONTROLLED RELEASE

Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications

(2018) Wei Wu et al.   Theranostics

Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway

(2018) Jianqin Lu et al.   ACS Nano

Study on the effectiveness of ligand reversible shielding strategy in targeted delivery and tumor therapy

(2018) Zhenpeng Hu et al.   Acta Biomaterialia

Targeted codelivery of doxorubicin and IL-36γ expression plasmid for an optimal chemo-gene combination therapy against cancer lung metastasis

(2018) Yichao Chen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy

(2017) Xiaoyuan Wang et al.   MACROMOLECULAR BIOSCIENCE

Combined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment

(2017) Chun Li et al.   Biomaterials Science

Synthesis and application of poly(ethylene glycol)-co-poly(β-amino ester) copolymers for small cell lung cancer gene therapy

(2016) Jayoung Kim et al.   Acta Biomaterialia

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA

(2016) Cong Luo et al.   BIOMATERIALS

Metformin: An anti-diabetic drug to fight cancer

(2016) Marie Daugan et al.   PHARMACOLOGICAL RESEARCH

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

(2016) Yi Zhao et al.   Nature Communications

Synthesis of diblock/statistical cationic glycopolymers with pendant galactose and lysine moieties: gene delivery application and intracellular behaviors

(2016) Jingjing Sun et al.   Journal of Materials Chemistry B

Harnessing the PEG-cleavable strategy to balance cytotoxicity, intracellular release and the therapeutic effect of dendrigraft poly-l-lysine for cancer gene therapy

(2016) Min Tang et al.   Journal of Materials Chemistry B

Production and clinical development of nanoparticles for gene delivery

(2016) Jie Chen et al.   Molecular Therapy-Methods & Clinical Development

Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment

(2015) Lin Kang et al.   Acta Pharmaceutica Sinica B

Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

(2014) Alba Luengo et al.   BMC BIOLOGY

Metformin-Loaded BSA Nanoparticles in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug

(2014) Pinkybel Jose et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Carbohydrate-Based Nanogels as Drug and Gene Delivery Systems

(2014) Saji Uthaman et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Charge-Conversional and pH-Sensitive PEGylated Polymeric Micelles as Efficient Nanocarriers for Drug Delivery

(2014) Gong-Yan Liu et al.   MACROMOLECULAR BIOSCIENCE

Polymer gene delivery: overcoming the obstacles

(2013) Ahmed Aied et al.   DRUG DISCOVERY TODAY

Efficient siRNA delivery and tumor accumulation mediated by ionically cross-linked folic acid–poly(ethylene glycol)–chitosan oligosaccharide lactate nanoparticles: For the potential targeted ovarian cancer gene therapy

(2013) Tony Shing Chau Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Biodegradable cationic polymeric nanocapsules for overcoming multidrug resistance and enabling drug–gene co-delivery to cancer cells

(2013) Chih-Kuang Chen et al.   Nanoscale

Facile Synthesis of a Fluorescent Cyclosporin A Analogue To Study Cyclophilin 40 and Cyclophilin 18 Ligands

(2010) Steffen Gaali et al.   ACS Medicinal Chemistry Letters