Combined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment

Physiological and Pharmacological Control of BAK, BAX, and Beyond

(2016) Mark P.A. Luna-Vargas et al.   TRENDS IN CELL BIOLOGY

The proteasome inhibitor Bortezomib (Velcade) as potential inhibitor of estrogen receptor-positive breast cancer

(2015) Sonja Thaler et al.   INTERNATIONAL JOURNAL OF CANCER

Progresses towards safe and efficient gene therapy vectors

(2015) Sergiu Chira et al.   Oncotarget

Tumor extracellular acidity activated “off–on” release of bortezomib from a biocompatible dendrimer

(2015) Mingming Wang et al.   Biomaterials Science

Small interfering RNA delivery by polyethylenimine-functionalised porous silicon nanoparticles

(2015) M. Hasanzadeh Kafshgari et al.   Biomaterials Science

Hydrophilic Molybdenum Oxide Nanomaterials with Controlled Morphology and Strong Plasmonic Absorption for Photothermal Ablation of Cancer Cells

(2014) Guosheng Song et al.   ACS Applied Materials & Interfaces

A universal gene carrier platform for treatment of human prostatic carcinoma by p53 transfection

(2014) Lu Han et al.   BIOMATERIALS

Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis

(2014) Tao Yu et al.   CELL RESEARCH

D-Cyclins Repress Apoptosis in Hematopoietic Cells by Controlling Death Receptor Fas and Its Ligand FasL

(2014) Yoon Jong Choi et al.   DEVELOPMENTAL CELL

Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function

(2014) Jia Shen et al.   Cell Reports

A Low-Toxic Multifunctional Nanoplatform Based on Cu9S5@mSiO2Core-Shell Nanocomposites: Combining Photothermal- and Chemotherapies with Infrared Thermal Imaging for Cancer Treatment

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The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy

(2013) Jia Shen et al.   BIOMATERIALS

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis

(2012) Fan Yang et al.   CANCER BIOLOGY & THERAPY

Functionalized mesoporous silica materials for controlled drug delivery

(2012) Piaoping Yang et al.   CHEMICAL SOCIETY REVIEWS

Bortezomib: a proteasome inhibitor with an evolving role in select subtypes of B-cell non-Hodgkin’s lymphoma

(2012) Jamie L Koprivnikar et al.   Future Oncology

Mesoporous silicananoparticles for the design of smart delivery nanodevices

(2012) Montserrat Colilla et al.   Biomaterials Science

p14ARFinhibits the functions of adenovirus E1A oncoprotein

(2011) Jia Shen et al.   BIOCHEMICAL JOURNAL

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

(2011) D. Chen et al.   CURRENT CANCER DRUG TARGETS

Phase 2 study of frontline bortezomib in patients with advanced non-small cell lung cancer

(2011) Benjamin Besse et al.   LUNG CANCER

Bortezomib and dexamethasone induction for multiple myeloma

(2010) Jacob Laubach et al.   Nature Reviews Clinical Oncology

CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells

(2010) K-F Chen et al.   ONCOGENE

Phase II study of the proteasome inhibitor bortezomib (PS-341, Velcade®) in chemotherapy-naïve patients with advanced stage non-small cell lung cancer (NSCLC)

(2009) Tianhong Li et al.   LUNG CANCER

Bortezomib induces schedule-dependent modulation of gemcitabine pharmacokinetics and pharmacodynamics in non-small cell lung cancer and blood mononuclear cells

(2009) C. Ceresa et al.   MOLECULAR CANCER THERAPEUTICS

Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway

(2008) M. Lioni et al.   MOLECULAR CANCER THERAPEUTICS

Cancer gene therapy using adeno-associated virus vectors

(2007) Keerang Park   Frontiers in Bioscience-Landmark