Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

Beyond the boundaries of cardiology: Still untapped anticancer properties of the cardiovascular system-related drugs

(2019) Katarzyna Regulska et al.   PHARMACOLOGICAL RESEARCH

Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor

(2018) Ji-Chang Wang et al.   CANCER SCIENCE

Statins reduce testicular and ocular VEGF: A potential compromise to microcirculation

(2018) Nuran Ekerbicer et al.   MICROVASCULAR RESEARCH

Atorvastatin enhances endothelial adherens junctions through promoting VE-PTP gene transcription and reducing VE-cadherin-Y731 phosphorylation

(2018) Zihe Huo et al.   VASCULAR PHARMACOLOGY

Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels

(2018) M. R. de Vries et al.   JOURNAL OF INTERNAL MEDICINE

Evaluating the Efficacy of Atorvastatin on Patients with Carotid Plaque by an Innovative Ultrasonography

(2018) Yi-Cheng Zhu et al.   Journal of Stroke & Cerebrovascular Diseases

Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis

(2017) Laura Parma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Therapeutic targeting of the angiopoietin–TIE pathway

(2017) Pipsa Saharinen et al.   NATURE REVIEWS DRUG DISCOVERY

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

(2017) Martin Teichert et al.   Nature Communications

Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization

(2017) Reginald V.C.T. van der Kwast et al.   CIRCULATION RESEARCH

Cholesterol-independent effects of atorvastatin prevent cardiovascular morbidity and mortality in a mouse model of atherosclerotic plaque rupture

(2016) Lynn Roth et al.   VASCULAR PHARMACOLOGY

Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia

(2014) Sabine M.J. Welten et al.   CIRCULATION RESEARCH

Atorvastatin Improves Plaque Stability in ApoE-Knockout Mice by Regulating Chemokines and Chemokine Receptors

(2014) Peng Nie et al.   PLoS One

Statin therapy prevents expansive remodeling in venous bypass grafts

(2012) Beiping Qiang et al.   ATHEROSCLEROSIS

Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

(2012) Margreet R. de Vries et al.   PLoS One

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

(2012) Fabrizio Orsenigo et al.   Nature Communications

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels

(2010) Ilze Bot et al.   ATHEROSCLEROSIS

Immaturity of microvessels in haemorrhagic plaques is associated with proteolytic degradation of angiogenic factors

(2009) J. Le Dall et al.   CARDIOVASCULAR RESEARCH

Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis

(2009) Judith C Sluimer et al.   JOURNAL OF PATHOLOGY

Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions

(2009) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Angiopoietin-1 Prevents VEGF-Induced Endothelial Permeability by Sequestering Src through mDia

(2008) Julie Gavard et al.   DEVELOPMENTAL CELL

The role of adherens junctions and VE-cadherin in the control of vascular permeability

(2008) E. Dejana et al.   JOURNAL OF CELL SCIENCE

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

(2008) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Protein kinase C   promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor

(2007) H. Xu et al.   CARDIOVASCULAR RESEARCH