G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3β and stabilizing β-catenin

Aberrant WNT/CTNNB1 Signaling as a Therapeutic Target in Human Breast Cancer: Weighing the Evidence

(2020) Emma H. van Schie et al.   Frontiers in Cell and Developmental Biology

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

The RNA-Binding Protein Rasputin/G3BP Enhances the Stability and Translation of Its Target mRNAs

(2020) John D. Laver et al.   Cell Reports

Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome

(2020) Je-Hwan Lee et al.   Blood Advances

Loss of G3BP1 suppresses proliferation, migration, and invasion of esophageal cancer cells via Wnt/β‐catenin and PI3K/AKT signaling pathways

(2019) Li‐Na Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis

(2019) Yong Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer

(2019) Rui Xiong et al.   OncoTargets and Therapy

Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection

(2019) Hongmei Zheng et al.   Cancer Medicine

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer

(2019) Kai Li et al.   ONCOGENE

G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response

(2019) Wenping Yang et al.   Cell Death & Disease

G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas

(2018) Yong Wang et al.   Cell Death & Disease

Rasputin a decade on and more promiscuous than ever? A review of G3BPs

(2018) Umber Alam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists

(2018) Ping Yin et al.   CANCER SCIENCE

MiR-128-3p accelerates cardiovascular calcification and insulin resistance through ISL1-dependent Wnt pathway in type 2 diabetes mellitus rats

(2018) Xin-Yong Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

G3BP1 promotes DNA binding and activation of cGAS

(2018) Zhao-Shan Liu et al.   NATURE IMMUNOLOGY

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Mammary Development and Breast Cancer: A Wnt Perspective

(2016) Qing Yu et al.   Cancers

Wnt/ -Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells

(2015) G.-B. Jang et al.   CANCER RESEARCH

Wnt Signaling Regulates Blood Pressure by Downregulating a GSK-3β–Mediated Pathway to Enhance Insulin Signaling in the Central Nervous System

(2015) Pei-Wen Cheng et al.   DIABETES

Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients

(2015) Lingqiang Min et al.   HISTOPATHOLOGY

Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway

(2015) Hao Zhang et al.   Oncotarget

Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype

(2015) Gyu-Beom Jang et al.   Scientific Reports

Small Molecule Inhibitors of Wnt/β-Catenin/Lef-1 Signaling Induces Apoptosis in Chronic Lymphocytic Leukemia Cells In Vitro and In Vivo

(2015) Rajesh Kumar Gandhirajan et al.   NEOPLASIA

Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway

(2013) H Zhang et al.   CANCER GENE THERAPY

Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells

(2013) Sofia Winslow et al.   Molecular Cancer

GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells

(2012) Hao Zhang et al.   CANCER SCIENCE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab

(2011) Stefan Glück et al.   BREAST CANCER RESEARCH AND TREATMENT

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

Arginine methylation of G3BP1 in response to Wnt3a regulates  -catenin mRNA

(2011) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome

(2010) Andrey I. Khramtsov et al.   AMERICAN JOURNAL OF PATHOLOGY

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

(2010) Felipe C Geyer et al.   MODERN PATHOLOGY

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

(2010) S. A. Ettenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

The Wnt-5a-Derived Hexapeptide Foxy-5 Inhibits Breast Cancer Metastasis In vivo by Targeting Cell Motility

(2008) A. Safholm et al.   CLINICAL CANCER RESEARCH