mRNA-Activated Multifunctional DNAzyme Nanotweezer for Intracellular mRNA Sensing and Gene Therapy

Structure-Dependent Biodistribution of Liposomal Spherical Nucleic Acids

(2020) Jennifer R. Ferrer et al.   ACS Nano

Bioinspired Framework Nucleic Acid Capture Sensitively and Rapidly Resolving MicroRNAs Biomarkers in Living Cells

(2020) Fan Yang et al.   ANALYTICAL CHEMISTRY

A Smart, Autocatalytic, DNAzyme Biocircuit for in Vivo, Amplified, MicroRNA Imaging

(2020) Jie Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A smart theranostic nanocapsule for spatiotemporally programmable photo‐genetherapy

(2020) Xue Gong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Framework nucleic acids as programmable carrier for transdermal drug delivery

(2019) Christian Wiraja et al.   Nature Communications

Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

(2019) Angela C. Stelson et al.   Nature Communications

DNAzyme-Loading MOFs for Self-Sufficient Gene Therapy

(2019) Huimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrahedral DNA Nanostructure-Delivered DNAzyme for Gene Silencing to Suppress Cell Growth

(2019) Lingxian Meng et al.   ACS Applied Materials & Interfaces

Metal-Organic Framework (MOF) Hybrid as a Tandem Catalyst for Enhanced Therapy against Hypoxic Tumor Cells

(2019) Jintong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme-Driven Assembly and Disassembly of Hybrid DNA–RNA Nanotubes

(2019) Siddharth Agarwal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures

(2019) Megan E. Kizer et al.   Small

Triplex DNA Nanoswitch for pH-Sensitive Release of Multiple Cancer Drugs

(2019) Xiaoxia Chen et al.   ACS Nano

Triple-Targeting Delivery of CRISPR/Cas9 to Reduce the Risk of Cardiovascular Diseases

(2019) Lingmin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Camptothecin-Grafted DNA Tetrahedron as Precise Nanomedicine to Inhibit the Tumor Growth

(2019) Jiao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation

(2019) Lei Miao et al.   NATURE BIOTECHNOLOGY

Functional DNA hexahedron for real-time detection of multiple microRNAs in living cells

(2019) Jinhong Dong et al.   ANALYTICA CHIMICA ACTA

A Nanobody-Conjugated DNA Nanoplatform for Targeted Platinum-Drug Delivery

(2019) Tiantian Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A DNA-Azobenzene Nanopump Fueled by Upconversion Luminescence for Controllable Intracellular Drug Release

(2019) Yue Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

(2019) Jianbing Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

(2019) Paul S. Kwon et al.   Nature Chemistry

Aptamer-Functionalized DNA Origami for Targeted Codelivery of Antisense Oligonucleotides and Doxorubicin to Enhance Therapy in Drug-Resistant Cancer Cells

(2019) Qingshan Pan et al.   ACS Applied Materials & Interfaces

Isothermal Self-Assembly of Spermidine–DNA Nanostructure Complex as a Functional Platform for Cancer Therapy

(2018) Dong Wang et al.   ACS Applied Materials & Interfaces

Cross-Platform Cancer Cell Identification Using Telomerase-Specific Spherical Nucleic Acids

(2018) Zhengjie Liu et al.   ACS Nano

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

(2018) Miguel M. Lino et al.   ACS Nano

Rapid Photoactuation of a DNA Nanostructure using an Internal Photocaged Trigger Strand

(2018) Minghui Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Situ Synthesis of Ultrathin ZIF-8 Film-Coated MSNs for Codelivering Bcl 2 siRNA and Doxorubicin to Enhance Chemotherapeutic Efficacy in Drug-Resistant Cancer Cells

(2018) Qing-Shan Pan et al.   ACS Applied Materials & Interfaces

Spatial Regulation of Biomolecular Interactions with a Switchable Trident-Shaped DNA Nanoactuator

(2018) Chao Xing et al.   ACS Applied Materials & Interfaces

Functional-DNA-Driven Dynamic Nanoconstructs for Biomolecule Capture and Drug Delivery

(2018) Jinhwan Kim et al.   ADVANCED MATERIALS

A DNA Octahedron-based Fluorescence Nanoprobe for Dual Tumor-related mRNAs Detection and Imaging

(2018) Lin Zhong et al.   ANALYTICAL CHEMISTRY

Mitochondria-Targeted DNA Nanoprobe for Real-Time Imaging and Simultaneous Quantification of Ca2+ and pH in Neurons

(2018) Zhichao Liu et al.   ACS Nano

Versatile Catalytic Deoxyribozyme Vehicles for Multimodal Imaging-Guided Efficient Gene Regulation and Photothermal Therapy

(2018) Jie Feng et al.   ACS Nano

A DNA Walker as a Fluorescence Signal Amplifier

(2017) Dongfang Wang et al.   NANO LETTERS

Genome Editing for Cancer Therapy: Delivery of Cas9 Protein/sgRNA Plasmid via a Gold Nanocluster/Lipid Core-Shell Nanocarrier

(2017) Peng Wang et al.   Advanced Science

Multicolor-Encoded Reconfigurable DNA Nanostructures Enable Multiplexed Sensing of Intracellular MicroRNAs in Living Cells

(2016) Wenjiao Zhou et al.   ACS Applied Materials & Interfaces

Optimized DNA “Nanosuitcases” for Encapsulation and Conditional Release of siRNA

(2016) Katherine E. Bujold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescence resonance energy transfer-based hybridization chain reaction for in situ visualization of tumor-related mRNA

(2016) Jin Huang et al.   Chemical Science

A Smart DNAzyme-MnO2Nanosystem for Efficient Gene Silencing

(2015) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly sensitive fluorescence detection of target DNA by coupling exonuclease-assisted cascade target recycling and DNAzyme amplification

(2015) Shufeng Liu et al.   BIOSENSORS & BIOELECTRONICS

FRET Nanoflares for Intracellular mRNA Detection: Avoiding False Positive Signals and Minimizing Effects of System Fluctuations

(2015) Yanjing Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery

(2014) Rong Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Behavior of DNA Cages Anchored on Spherically Supported Lipid Bilayers

(2014) J. W. Conway et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A DNA tweezer-actuated enzyme nanoreactor

(2013) Minghui Liu et al.   Nature Communications

Amplified Surface Plasmon Resonance and Electrochemical Detection of Pb2+ Ions Using the Pb2+-Dependent DNAzyme and Hemin/G-Quadruplex as a Label

(2012) Gilad Pelossof et al.   ANALYTICAL CHEMISTRY

A Multicolor Nanoprobe for Detection and Imaging of Tumor-Related mRNAs in Living Cells

(2012) Na Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reversible Regulation of Protein Binding Affinity by a DNA Machine

(2012) Chao Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Discovery of Cationic Polymers for Non-Viral Gene Delivery Using Combinatorial Approaches

(2011) Sutapa Barua et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Deoxyribozymes: Selection Design and Serendipity in the Development of DNA Catalysts†

(2009) Scott K. Silverman   ACCOUNTS OF CHEMICAL RESEARCH

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS

Deoxyribozymes: useful DNA catalysts in vitro and in vivo

(2008) D. A. Baum et al.   CELLULAR AND MOLECULAR LIFE SCIENCES