Outer-membrane-acting peptides and lipid II-targeting antibiotics cooperatively kill Gram-negative pathogens

In vitro activity of oritavancin alone or in combination against vancomycin-susceptible and -resistant enterococci

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Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa

(2019) Imran Mohammed et al.   Frontiers in Microbiology

Synergistic Activities of Colistin Combinations with Meropenem, Sulbactam, Minocycline, Disodium Fosfomycin, or Vancomycin Against Different Clones of Carbapenem-Resistant Acinetobacter baumannii Strains

(2019) Ahmet Sertcelik et al.   Microbial Drug Resistance

Preclinical studies of toxicity and safety of the AS-48 bacteriocin

(2019) Rubén Cebrián et al.   Journal of Advanced Research

LL-37-derived short antimicrobial peptide KR-12-a5 and its d -amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional antibiotics, and anti-inflammatory activity

(2017) Eun Young Kim et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid-β 1-42

(2017) Devkee M. Vadukul et al.   FEBS LETTERS

Design, synthesis and evaluation of new ligustrazine derivatives as potential plasma-stable neuroprotective agents

(2017) Chenze Zhang et al.   MedChemComm

Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application

(2017) Christopher A. Kerantzas et al.   mBio

Synergistic effects of antimicrobial peptide DP7 combined with antibiotics against multidrug-resistant bacteria

(2017) Xiaozhe Wu et al.   Drug Design Development and Therapy

Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance

(2017) Jonathan M. Stokes et al.   Nature Microbiology

Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum

(2017) Roland Böttger et al.   PLoS One

Reflecting on the final report of the O'Neill Review on Antimicrobial Resistance

(2016) Laura J V Piddock   LANCET INFECTIOUS DISEASES

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens

(2016) Sirijan Santajit et al.   Biomed Research International

Bacteriocins and their position in the next wave of conventional antibiotics

(2015) Veronica L. Cavera et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs

(2015) Jiajun Wang et al.   Scientific Reports

Synergistic Interactions of Vancomycin with Different Antibiotics against Escherichia coli: Trimethoprim and Nitrofurantoin Display Strong Synergies with Vancomycin against Wild-Type E. coli

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Antibiotic Adjuvants: Diverse Strategies for Controlling Drug-Resistant Pathogens

(2014) Erin E. Gill et al.   Chemical Biology & Drug Design

Development of the ECODAB into a relational database for Escherichia coli O-antigens and other bacterial polysaccharides

(2014) M. A. Rojas-Macias et al.   GLYCOBIOLOGY

Effect of Divalent Cation Removal on the Structure of Gram-Negative Bacterial Outer Membrane Models

(2014) Luke A. Clifton et al.   LANGMUIR

Antimicrobial Activity of Peptides Derived from Olive Flounder Lipopolysaccharide Binding Protein/Bactericidal Permeability-Increasing Protein (LBP/BPI)

(2014) Bo-Hye Nam et al.   Marine Drugs

Electrostatic modification of the lipopolysaccharide layer: competing effects of divalent cations and polycationic or polyanionic molecules

(2014) Norman H. Lam, Zheng Ma et al.   Soft Matter

Synergistic Effect between Colistin and Bacteriocins in Controlling Gram-Negative Pathogens and Their Potential To Reduce Antibiotic Toxicity in Mammalian Epithelial Cells

(2013) Karim Naghmouchi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity

(2013) Binu Jacob et al.   JOURNAL OF PEPTIDE SCIENCE

Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides

(2013) Ankur Gautam et al.   NUCLEIC ACIDS RESEARCH

Effect of Sequence and Stereochemistry Reversal on p53 Peptide Mimicry

(2013) Alessio Atzori et al.   PLoS One

Correction: N-Acetylglucosamine Kinase, HXK1 Is Involved in Morphogenetic Transition and Metabolic Gene Expression in Candida albicans

(2013) Kongara Hanumantha Rao et al.   PLoS One

Api88 Is a Novel Antibacterial Designer Peptide To Treat Systemic Infections with Multidrug-Resistant Gram-Negative Pathogens

(2012) Patricia Czihal et al.   ACS Chemical Biology

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

(2012) Inês M. Torcato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences

(2012) Nada Ilić et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Comparison of the Potency of the Lipid II Targeting Antimicrobials Nisin, Lacticin 3147 and Vancomycin Against Gram-Positive Bacteria

(2012) Catalin Iancu et al.   Probiotics and Antimicrobial Proteins

Deciphering the Mode of Action of the Synthetic Antimicrobial Peptide Bac8c

(2011) E. C. Spindler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Improvement of the Efficacy of Linear Undecapeptides against Plant-Pathogenic Bacteria by Incorporation of d-Amino Acids

(2011) Imma Güell et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy

(2011) Linda Ejim et al.   Nature Chemical Biology

Pyrosequencing of Antibiotic-Contaminated River Sediments Reveals High Levels of Resistance and Gene Transfer Elements

(2011) Erik Kristiansson et al.   PLoS One

Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens

(2010) Daniel Knappe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibacterial activity of class I and IIa bacteriocins combined with polymyxin E against resistant variants of Listeria monocytogenes and Escherichia coli

(2010) Karim Naghmouchi et al.   RESEARCH IN MICROBIOLOGY

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Antibiotics for Emerging Pathogens

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