Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro

The loss of STAT3 in mature osteoclasts has detrimental effects on bone structure

(2020) Rebecca K. Davidson et al.   PLoS One

Epigenetic and transcriptional regulation of osteoclast differentiation

(2020) Daisuke Kurotaki et al.   BONE

Cooperation of PU.1 with IRF8 and NFATc1 defines chromatin landscapes during RANKL‐induced osteoclastogenesis

(2019) Naohiro Izawa et al.   JOURNAL OF BONE AND MINERAL RESEARCH

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα

(2017) Seyeon Bae et al.   JOURNAL OF CLINICAL INVESTIGATION

Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis

(2017) Ji-Eun Lee et al.   Nature Communications

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

(2016) David Langlais et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc

(2016) Chen Yu et al.   Scientific Reports

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

(2015) Jae-Seok Roe et al.   MOLECULAR CELL

Characterization of Functional Reprogramming during Osteoclast Development Using Quantitative Proteomics and mRNA Profiling

(2014) Eunkyung An et al.   MOLECULAR & CELLULAR PROTEOMICS

Osteoclasts: more than ‘bone eaters’

(2014) Julia F. Charles et al.   TRENDS IN MOLECULAR MEDICINE

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

(2014) Kyung-Hyun Park-Min et al.   Nature Communications

Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle

(2014) François Lamoureux et al.   Nature Communications

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Advances in the Regulation of Osteoclasts and Osteoclast Functions

(2013) B.F. Boyce   JOURNAL OF DENTAL RESEARCH

Activated Invariant NKT Cells Regulate Osteoclast Development and Function

(2011) M. Hu et al.   JOURNAL OF IMMUNOLOGY

The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3

(2011) S. Rahman et al.   MOLECULAR AND CELLULAR BIOLOGY

The Blimp1–Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis

(2010) Yoshiteru Miyauchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

(2010) K. Nishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

(2009) Baohong Zhao et al.   NATURE MEDICINE

The pathogenesis of the bone disease of multiple myeloma

(2008) Claire M. Edwards et al.   BONE

Atp6v0d2 Is an Essential Component of the Osteoclast-Specific Proton Pump That Mediates Extracellular Acidification in Bone Resorption

(2008) Haiping Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

(2008) Gary LeRoy et al.   MOLECULAR CELL

Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation

(2007) Meiheng Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY