SeMPI 2.0—A Web Server for PKS and NRPS Predictions Combined with Metabolite Screening in Natural Product Databases

StreptomeDB 3.0: an updated compendium of streptomycetes natural products

(2020) Aurélien F A Moumbock et al.   NUCLEIC ACIDS RESEARCH

Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure-Selectivity Relationship of a Ketoreductase

(2019) Matthias Häckh et al.   CHEMBIOCHEM

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

A Review of the Microbial Production of Bioactive Natural Products and Biologics

(2019) Janette V. Pham et al.   Frontiers in Microbiology

MIBiG 2.0: a repository for biosynthetic gene clusters of known function

(2019) Satria A Kautsar et al.   NUCLEIC ACIDS RESEARCH

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

D3GB: An Interactive Genome Browser for R, Python, and WordPress

(2017) David Barrios et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

NANPDB: A Resource for Natural Products from Northern African Sources

(2017) Fidele Ntie-Kang et al.   JOURNAL OF NATURAL PRODUCTS

SBSPKSv2: structure-based sequence analysis of polyketide synthases and non-ribosomal peptide synthetases

(2017) Shradha Khater et al.   NUCLEIC ACIDS RESEARCH

SeMPI: a genome-based secondary metabolite prediction and identification web server

(2017) Paul F. Zierep et al.   NUCLEIC ACIDS RESEARCH

PRISM 3: expanded prediction of natural product chemical structures from microbial genomes

(2017) Michael A. Skinnider et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Total Synthesis and Biological Evaluation of Rakicidin A and Discovery of a Simplified Bioactive Analogue

(2015) Michail Tsakos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes

(2015) Dennis Klementz et al.   NUCLEIC ACIDS RESEARCH

Norine, the knowledgebase dedicated to non-ribosomal peptides, is now open to crowdsourcing

(2015) Areski Flissi et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis

(2013) Jonathan R. Whicher et al.   CHEMISTRY & BIOLOGY

The role of transcription in heterologous expression of polyketides in bacterial hosts

(2013) D. Cole Stevens et al.   NATURAL PRODUCT REPORTS

Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models

(2013) Barzan I. Khayatt et al.   PLoS One

Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses

(2013) A. Kampa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JSME: a free molecule editor in JavaScript

(2013) Bruno Bienfait et al.   Journal of Cheminformatics

ZINC: A Free Tool to Discover Chemistry for Biology

(2012) John J. Irwin et al.   Journal of Chemical Information and Modeling

The structures of type I polyketide synthases

(2012) Adrian T. Keatinge-Clay   NATURAL PRODUCT REPORTS

NRPSsp: non-ribosomal peptide synthase substrate predictor

(2011) Carlos Prieto et al.   BIOINFORMATICS

Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite

(2011) Katja M. Fisch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Prodigal: prokaryotic gene recognition and translation initiation site identification

(2010) Doug Hyatt et al.   BMC BIOINFORMATICS

SBSPKS: structure based sequence analysis of polyketide synthases

(2010) Swadha Anand et al.   NUCLEIC ACIDS RESEARCH

Automated genome mining for natural products

(2009) Michael HT Li et al.   BMC BIOINFORMATICS

Towards Prediction of Metabolic Products of Polyketide Synthases: An In Silico Analysis

(2009) Gitanjali Yadav et al.   PLoS Computational Biology

Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed β-Alanine as Precursor of the Pyridone Moiety

(2008) Tilmann Weber et al.   CHEMISTRY & BIOLOGY

Identification of the Bray-Curtis similarity index: Comment on Yoshioka (2008)

(2008) PJ Somerfield   MARINE ECOLOGY PROGRESS SERIES

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY