Enlisting the Ixodes scapularis Embryonic ISE6 Cell Line to Investigate the Neuronal Basis of Tick—Pathogen Interactions

Cholinergic axons regulate type I acini in salivary glands of Ixodes ricinus and Ixodes scapularis ticks

(2020) Lourdes Mateos-Hernandéz et al.   Scientific Reports

Pathogens Manipulating Tick Behavior—Through a Glass, Darkly

(2020) Giovanni Benelli   Pathogens

The leucokinin-like peptide receptor from the cattle fever tick, Rhipicephalus microplus, is localized in the midgut periphery and receptor silencing with validated double-stranded RNAs causes a reproductive fitness cost

(2019) Christina M. Brock et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Tick–Pathogen Interactions: The Metabolic Perspective

(2019) Alejandro Cabezas-Cruz et al.   TRENDS IN PARASITOLOGY

Ultrastructural mapping of salivary gland innervation in the tick Ixodes ricinus

(2019) Marie Vancová et al.   Scientific Reports

Anaplasma phagocytophilum modifies tick cell microRNA expression and upregulates isc-mir-79 to facilitate infection by targeting the Roundabout protein 2 pathway

(2019) Sara Artigas-Jerónimo et al.   Scientific Reports

Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic

(2019) Dick R. Nässel et al.   Frontiers in Neuroscience

Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd

(2018) Cornelia Silaghi et al.   Parasites & Vectors

Molecular characterization of neuropeptide elevenin and two elevenin receptors, IsElevR1 and IsElevR2, from the blacklegged tick, Ixodes scapularis

(2018) Donghun Kim et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Remodeling of tick cytoskeleton in response to infection with i Anaplasma phagocytophilum i

(2017) Jose de la Fuente   Frontiers in Bioscience-Landmark

DINeR: Database for Insect Neuropeptide Research

(2017) Joseph G.C. Yeoh et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Infection-derived lipids elicit an immune deficiency circuit in arthropods

(2017) Dana K. Shaw et al.   Nature Communications

Ixodes scapularis Tick Cells Control Anaplasma phagocytophilum Infection by Increasing the Synthesis of Phosphoenolpyruvate from Tyrosine

(2017) Alejandro Cabezas-Cruz et al.   Frontiers in Cellular and Infection Microbiology

Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis

(2017) Alejandro Cabezas-Cruz et al.   Frontiers in Cellular and Infection Microbiology

Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

(2017) José de la Fuente et al.   Frontiers in Cellular and Infection Microbiology

Endocrine regulation of insect diuresis in the early postgenomic era1This review is part of a virtual symposium on recent advances in understanding a variety of complex regulatory processes in insect physiology and endocrinology, including development, metabolism, cold hardiness, food intake and digestion, and diuresis, through the use of omics technologies in the postgenomic era.

(2017) Yoonseong Park   CANADIAN JOURNAL OF ZOOLOGY

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

(2016) Monika Gulia-Nuss et al.   Nature Communications

Ligand selectivity in tachykinin and natalisin neuropeptidergic systems of the honey bee parasitic mite Varroa destructor

(2016) Hongbo Jiang et al.   Scientific Reports

Changes in the Proteome of Langat-Infected Ixodes scapularis ISE6 Cells: Metabolic Pathways Associated with Flavivirus Infection

(2016) Jeffrey M. Grabowski et al.   PLoS Neglected Tropical Diseases

Tick–Host–Pathogen Interactions: Conflict and Cooperation

(2016) José de la Fuente et al.   PLoS Pathogens

Tissue-Specific Signatures in the Transcriptional Response to Anaplasma phagocytophilum Infection of Ixodes scapularis and Ixodes ricinus Tick Cell Lines

(2016) Pilar Alberdi et al.   Frontiers in Cellular and Infection Microbiology

An Ixodes scapularis cell line with a predominantly neuron-like phenotype

(2015) Jonathan D. Oliver et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected byAnaplasma phagocytophilumInfection in Tick Cells

(2015) Margarita Villar et al.   MOLECULAR & CELLULAR PROTEOMICS

The genus Anaplasma: new challenges after reclassification

(2015) K.M. KOCAN et al.   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis

(2015) Nieves Ayllón et al.   PLoS Genetics

Bioinformatic and mass spectrometry identification of Anaplasma phagocytophilum proteins translocated into host cell nuclei

(2015) Sara H. G. Sinclair et al.   Frontiers in Microbiology

Tissue Distribution of the Ehrlichia muris-Like Agent in a Tick Vector

(2015) Geoffrey E. Lynn et al.   PLoS One

Effector bottleneck: microbial reprogramming of parasitized host cell transcription by epigenetic remodeling of chromatin structure

(2014) Sara H. Sinclair et al.   Frontiers in Genetics

Receptors for the neuropeptides, myoinhibitory peptide and SIFamide, in control of the salivary glands of the blacklegged tick Ixodes scapularis

(2013) Ladislav Šimo et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Validation of Internal Reference Genes for Real-Time Quantitative Polymerase Chain Reaction Studies in the Tick,Ixodes scapularis(Acari: Ixodidae)

(2013) Juraj Koči et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Natalisin, a tachykinin-like signaling system, regulates sexual activity and fecundity in insects

(2013) H. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anaplasma odocoilei sp. nov. (family Anaplasmataceae) from white-tailed deer (Odocoileus virginianus)

(2012) Cynthia M. Tate et al.   Ticks and Tick-Borne Diseases

More than two decades of research on insect neuropeptide GPCRs: an overview

(2012) Jelle Caers et al.   Frontiers in Endocrinology

Expression of heat shock proteins and subolesin affects stress responses, Anaplasma phagocytophilum infection and questing behaviour in the tick, Ixodes scapularis

(2011) A. T. BUSBY et al.   MEDICAL AND VETERINARY ENTOMOLOGY

Global Proteomic Analysis of Two Tick-Borne Emerging Zoonotic Agents: Anaplasma Phagocytophilum and Ehrlichia Chaffeensis

(2011) Mingqun Lin et al.   Frontiers in Microbiology

Wide Dispersal and Possible Multiple Origins of Low-Copy-Number Plasmids in Rickettsia Species Associated with Blood-Feeding Arthropods

(2010) G. D. Baldridge et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Invasion of the Lyme Disease Vector Ixodes scapularis: Implications for Borrelia burgdorferi Endemicity

(2010) Sarah A. Hamer et al.   EcoHealth

Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold

(2010) Girish Neelakanta et al.   JOURNAL OF CLINICAL INVESTIGATION

Toward a consensus nomenclature for insect neuropeptides and peptide hormones

(2010) Geoffrey M. Coast et al.   PEPTIDES

Ixodes ovatus Ehrlichia Exhibits Unique Ultrastructural Characteristics in Mammalian Endothelial and Tick-derived Cells

(2009) Ulrike G. Munderloh et al.   Annals of the New York Academy of Sciences

Two novel neuropeptides in innervation of the salivary glands of the black-legged tick,Ixodes scapularis: Myoinhibitory peptide and SIFamide

(2009) Ladislav Šimo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The neuropeptidomics of Ixodes scapularis synganglion

(2009) Susanne Neupert et al.   Journal of Proteomics

Identification of a complex peptidergic neuroendocrine network in the hard tick, Rhipicephalus appendiculatus

(2008) Ladislav Šimo et al.   CELL AND TISSUE RESEARCH

Neuropeptide discovery in Ixodoidea: An in silico investigation using publicly accessible expressed sequence tags

(2008) Andrew E. Christie   GENERAL AND COMPARATIVE ENDOCRINOLOGY