Plant-made pharmaceuticals: Leading products and production platforms

Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma

(2010) M. Bendandi et al.   ANNALS OF ONCOLOGY

Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture

(2010) T. Holland et al.   BIOTECHNOLOGY AND BIOENGINEERING

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

(2010) Yao-Ming Huang et al.   BIOTECHNOLOGY PROGRESS

Production of antibodies in plants: status after twenty years

(2010) Benoit De Muynck et al.   PLANT BIOTECHNOLOGY JOURNAL

Solar-powered factories for new vaccines and antibiotics

(2010) Ralph Bock et al.   TRENDS IN BIOTECHNOLOGY

A DNA replicon system for rapid high-level production of virus-like particles in plants

(2009) Zhong Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco

(2009) Pascal M. W. Drake et al.   FASEB JOURNAL

Sales of biologics to show robust growth through to 2013

(2009) Michael Goodman   NATURE REVIEWS DRUG DISCOVERY

Transient co-expression for fast and high-yield production of antibodies with human-likeN-glycans in plants

(2009) Louis-P. Vézina et al.   PLANT BIOTECHNOLOGY JOURNAL

pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants

(2009) Frank Sainsbury et al.   PLANT BIOTECHNOLOGY JOURNAL

A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

(2009) David Aviezer et al.   PLoS One

Optimisation of contained Nicotiana tabacum cultivation for the production of recombinant protein pharmaceuticals

(2009) Richard Colgan et al.   TRANSGENIC RESEARCH

Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

(2008) Alain Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Novel Controlled-Release Lemna-Derived IFN-α2b (Locteron): Pharmacokinetics, Pharmacodynamics, and Tolerability in a Phase I Clinical Trial

(2008) Leo G.J. De Leede et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Molecular pharming in cereal crops

(2008) Koreen Ramessar et al.   PHYTOCHEMISTRY REVIEWS

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: Safety and immunogenicity in a phase I clinical study

(2008) A. A. McCormick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA