Streamlining Natural Products Biomanufacturing With Omics and Machine Learning Driven Microbial Engineering
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Streamlining Natural Products Biomanufacturing With Omics and Machine Learning Driven Microbial Engineering
Authors
Keywords
-
Journal
Frontiers in Bioengineering and Biotechnology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-12-21
DOI
10.3389/fbioe.2020.608918
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identifying Missing Biosynthesis Enzymes of Plant Natural Products
- (2020) Thomas Dugé de Bernonville et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Promoter library based pathway optimization for efficient (2S)-naringenin production from p-coumaric acid in Saccharomyces cerevisiae
- (2020) Song Gao et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
- (2020) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Systems and synthetic biology tools for advanced bioproduction hosts
- (2020) Yan Chen et al. CURRENT OPINION IN BIOTECHNOLOGY
- Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers
- (2020) Christopher J. Robinson et al. METABOLIC ENGINEERING
- Synthesizing Systems Biology Knowledge from Omics Using Genome‐Scale Models
- (2020) Sanjeev Dahal et al. PROTEOMICS
- Biosystems Design by Machine Learning
- (2020) Michael Jeffrey Volk et al. ACS Synthetic Biology
- Systematic Multi-Omics Integration (MOI) Approach in Plant Systems Biology
- (2020) Ili Nadhirah Jamil et al. Frontiers in Plant Science
- A machine learning Automated Recommendation Tool for synthetic biology
- (2020) Tijana Radivojević et al. Nature Communications
- Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism
- (2020) Jie Zhang et al. Nature Communications
- Engineering Plant Secondary Metabolism in Microbial Systems
- (2019) Michael E Pyne et al. PLANT PHYSIOLOGY
- Rapid Assembly of Yeast Expression Cassettes for Phenylpropanoid Biosynthesis in Saccharomyces cerevisiae
- (2019) Ahmad Bazli Ramzi et al. Sains Malaysiana
- Current Progress in Production of Flavonoids using Systems and Synthetic Biology Platforms
- (2019) Ku Nurul Aqmar Ku Bahaudin et al. Sains Malaysiana
- Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium
- (2019) Yu Ping et al. ACS Synthetic Biology
- Systems Metabolic Engineering Strategies: Integrating Systems and Synthetic Biology with Metabolic Engineering
- (2019) Kyeong Rok Choi et al. TRENDS IN BIOTECHNOLOGY
- Complete biosynthesis of cannabinoids and their unnatural analogues in yeast
- (2019) Xiaozhou Luo et al. NATURE
- Systems Metabolic Engineering Meets Machine Learning: A New Era for Data‐Driven Metabolic Engineering
- (2019) Kristin V. Presnell et al. Biotechnology Journal
- Machine learning-assisted directed protein evolution with combinatorial libraries
- (2019) Zachary Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning
- (2019) Paul Opgenorth et al. ACS Synthetic Biology
- Approaches to Computational Strain Design in the Multiomics Era
- (2019) Peter C. St. John et al. Frontiers in Microbiology
- De Novo Production of the Plant-Derived Tropine and Pseudotropine in Yeast
- (2019) Yu Ping et al. ACS Synthetic Biology
- Opportunities at the Intersection of Synthetic Biology, Machine Learning, and Automation
- (2019) Pablo Carbonell et al. ACS Synthetic Biology
- Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose
- (2019) Gheorghe M. Borja et al. Microbial Cell Factories
- Engineering a microbial biosynthesis platform for de novo production of tropane alkaloids
- (2019) Prashanth Srinivasan et al. Nature Communications
- Machine learning applications in systems metabolic engineering
- (2019) Gi Bae Kim et al. CURRENT OPINION IN BIOTECHNOLOGY
- Beyond the semi-synthetic artemisinin: metabolic engineering of plant-derived anti-cancer drugs
- (2019) Ines Carqueijeiro et al. CURRENT OPINION IN BIOTECHNOLOGY
- A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology
- (2018) Arturo Casini et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae
- (2018) Yikang Zhou et al. METABOLIC ENGINEERING
- Functional Characterisation of New Sesquiterpene Synthase from the Malaysian Herbal Plant, Polygonum Minus
- (2018) Nor Rusdi et al. MOLECULES
- Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes
- (2018) Thu-Thuy T. Dang et al. Nature Chemical Biology
- Structural and kinetic studies of a novel nerol dehydrogenase from Persicaria minor , a nerol-specific enzyme for citral biosynthesis
- (2018) Cheng Seng Tan et al. PLANT PHYSIOLOGY AND BIOCHEMISTRY
- The Integration of Metabolomics and Next-Generation Sequencing Data to Elucidate the Pathways of Natural Product Metabolism in Medicinal Plants
- (2018) Federico Scossa et al. PLANTA MEDICA
- Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
- (2018) Lorenzo Caputi et al. SCIENCE
- Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches
- (2018) Xiaonan Liu et al. Nature Communications
- Toward Predictable 5′UTRs in Saccharomyces cerevisiae: Development of a yUTR Calculator
- (2018) Thomas Decoene et al. ACS Synthetic Biology
- Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli
- (2018) Adrian J. Jervis et al. ACS Synthetic Biology
- Recent advancements in fungal-derived fuel and chemical production and commercialization
- (2018) Holly Ekas et al. CURRENT OPINION IN BIOTECHNOLOGY
- Comparison of the metabolic response to over-production of p -coumaric acid in two yeast strains
- (2017) Angelica Rodriguez et al. METABOLIC ENGINEERING
- Integrated omics analysis of specialized metabolism in medicinal plants
- (2017) Amit Rai et al. PLANT JOURNAL
- Transcriptome analysis of Polygonum minus reveals candidate genes involved in important secondary metabolic pathways of phenylpropanoids and flavonoids
- (2017) Kok-Keong Loke et al. PeerJ
- Engineering Cellular Metabolism
- (2016) Jens Nielsen et al. CELL
- Natural Products as Sources of New Drugs from 1981 to 2014
- (2016) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Developing Commercial Production of Semi-Synthetic Artemisinin, and of β-Farnesene, an Isoprenoid Produced by Fermentation of Brazilian Sugar
- (2016) Kirsten R. Benjamin et al. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
- Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae
- (2016) James Kirby et al. METABOLIC ENGINEERING
- The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V fromSiraitia grosvenorii
- (2016) Maxim Itkin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering biosynthesis of the anticancer alkaloid noscapine in yeast
- (2016) Yanran Li et al. Nature Communications
- Characterizing Strain Variation in Engineered E. coli Using a Multi-Omics-Based Workflow
- (2016) Elizabeth Brunk et al. Cell Systems
- Using Genome-scale Models to Predict Biological Capabilities
- (2015) Edward J. O’Brien et al. CELL
- Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering
- (2015) Jorge Alonso-Gutierrez et al. METABOLIC ENGINEERING
- Transcriptome exploration for further understanding of the tropane alkaloids biosynthesis in Anisodus acutangulus
- (2015) Lijie Cui et al. MOLECULAR GENETICS AND GENOMICS
- Systems strategies for developing industrial microbial strains
- (2015) Sang Yup Lee et al. NATURE BIOTECHNOLOGY
- Stereochemical inversion of (S)-reticuline by a cytochrome P450 fusion in opium poppy
- (2015) Scott C Farrow et al. Nature Chemical Biology
- An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose
- (2015) William C DeLoache et al. Nature Chemical Biology
- Complete biosynthesis of opioids in yeast
- (2015) S. Galanie et al. SCIENCE
- Plant systems biology: insights, advances and challenges
- (2014) Bhavisha P. Sheth et al. PLANTA
- Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae
- (2014) Elena Fossati et al. Nature Communications
- Data access for the 1,000 Plants (1KP) project
- (2014) Naim Matasci et al. GigaScience
- Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest
- (2013) Mei Xiao et al. JOURNAL OF BIOTECHNOLOGY
- Engineering dynamic pathway regulation using stress-response promoters
- (2013) Robert H Dahl et al. NATURE BIOTECHNOLOGY
- Quantitative Design of Regulatory Elements Based on High-Precision Strength Prediction Using Artificial Neural Network
- (2013) Hailin Meng et al. PLoS One
- Frontiers in metabolic reconstruction and modeling of plant genomes
- (2012) S. M. D. Seaver et al. JOURNAL OF EXPERIMENTAL BOTANY
- Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy
- (2012) Isabel Desgagné-Penix et al. PLANT MOLECULAR BIOLOGY
- An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis
- (2011) Qi Tang et al. BMC GENOMICS
- Targeted proteomics for metabolic pathway optimization: Application to terpene production
- (2011) Alyssa M. Redding-Johanson et al. METABOLIC ENGINEERING
- The draft genome and transcriptome of Cannabis sativa
- (2011) Harm van Bakel et al. GENOME BIOLOGY
- Next is now: new technologies for sequencing of genomes, transcriptomes, and beyond
- (2009) Ryan Lister et al. CURRENT OPINION IN PLANT BIOLOGY
- Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants
- (2008) Peter J. Facchini et al. PLANT JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More