Determinants of Phagosomal pH During Host-Pathogen Interactions

Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation

(2020) Johannes Westman et al.   Frontiers in Immunology

Targeting Two-Pore Channels: Current Progress and Future Challenges

(2020) Xuhui Jin et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection

(2020) Johannes Westman et al.   Cell Host & Microbe

Revisiting the role of calcium in phagosome formation and maturation

(2019) Johannes Westman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mycobacterium tuberculosis releases an antacid that remodels phagosomes

(2019) Jeffrey Buter et al.   Nature Chemical Biology

Microbial response to acid stress: mechanisms and applications

(2019) Ningzi Guan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The phagocyte NOX2 NADPH oxidase in microbial killing and cell signaling

(2019) William M Nauseef   CURRENT OPINION IN IMMUNOLOGY

The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification

(2018) Vitaly Sedlyarov et al.   Cell Host & Microbe

How to build a phagosome: new concepts for an old process

(2018) Florence Niedergang et al.   CURRENT OPINION IN CELL BIOLOGY

The role of lipids in host-pathogen interactions

(2018) Glenn F. W. Walpole et al.   IUBMB LIFE

Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses

(2018) Joe Dan Dunn et al.   Frontiers in Immunology

Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

(2018) Johannes Westman et al.   mBio

Listeriolysin O: A phagosome-specific cytolysin revisited

(2018) Brittney N. Nguyen et al.   CELLULAR MICROBIOLOGY

Zinc Transporter Proteins

(2017) Abdulkerim Kasim Baltaci et al.   NEUROCHEMICAL RESEARCH

Tuning the ion selectivity of two-pore channels

(2017) Jiangtao Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein

(2017) Jianhua Zhao et al.   PLoS Pathogens

Chloride flux in phagocytes

(2016) Guoshun Wang   IMMUNOLOGICAL REVIEWS

The life cycle of phagosomes: formation, maturation, and resolution

(2016) Roni Levin et al.   IMMUNOLOGICAL REVIEWS

WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

(2016) Catherine M. Buckley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular replication ofStaphylococcus aureusin mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

(2015) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Phagocytic activity of monocytes, their subpopulations and granulocytes during post-transplant adverse events after hematopoietic stem cell transplantation

(2015) Michaela Döring et al.   IMMUNOBIOLOGY

The vacuolar-type H+-ATPase at a glance - more than a proton pump

(2014) M. E. Maxson et al.   JOURNAL OF CELL SCIENCE

Hv1 proton channels differentially regulate the pH of neutrophil and macrophage phagosomes by sustaining the production of phagosomal ROS that inhibit the delivery of vacuolar ATPases

(2014) Antoun El Chemaly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages

(2014) Johnathan Canton et al.   MOLECULAR BIOLOGY OF THE CELL

The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase

(2014) Sheena Claire Li et al.   MOLECULAR BIOLOGY OF THE CELL

Modulation of Phagosomal pH by Candida albicans Promotes Hyphal Morphogenesis and Requires Stp2p, a Regulator of Amino Acid Transport

(2014) Slavena Vylkova et al.   PLoS Pathogens

Two-pore channels (TPCs): Current controversies

(2013) Anthony J. Morgan et al.   BIOESSAYS

mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

(2013) Chunlei Cang et al.   CELL

How nascent phagosomes mature to become phagolysosomes

(2012) Gregory D. Fairn et al.   TRENDS IN IMMUNOLOGY

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis

(2011) Michael Carnell et al.   JOURNAL OF CELL BIOLOGY

Phagosome dynamics during phagocytosis by neutrophils

(2011) Pontus Nordenfelt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expression of the ompATb operon accelerates ammonia secretion and adaptation of Mycobacterium tuberculosis to acidic environments

(2011) Houhui Song et al.   MOLECULAR MICROBIOLOGY

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

(2011) D. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cation counterflux supports lysosomal acidification

(2010) Benjamin E. Steinberg et al.   JOURNAL OF CELL BIOLOGY

Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation

(2010) S. Weinert et al.   SCIENCE

The ClC-3 Cl−/H+Antiporter Becomes Uncoupled at Low Extracellular pH

(2009) James J. Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Autocatalytic processing of procathepsin B is triggered by proenzyme activity

(2008) Jerica Rozman Pungerčar et al.   FEBS Journal

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes

(2008) Austin R. Graves et al.   NATURE