Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

(2018) Lan Fang et al.   CANCER CELL

RNA N6-methyladenosine modification in cancers: current status and perspectives

(2018) Xiaolan Deng et al.   CELL RESEARCH

N 6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential

(2018) Dandan Yang et al.   NUCLEIC ACIDS RESEARCH

YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

(2018) Xuhao Ni et al.   Cancer Discovery

Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria

(2018) Yang Wang et al.   NATURE CELL BIOLOGY

Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway

(2018) Zhiqiang Li et al.   CANCER CELL

CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells

(2018) Gang Liu et al.   Molecular Cancer

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

(2018) Lei Chang et al.   NATURE

A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1

(2017) Wen Ni et al.   Journal of Hematology & Oncology

Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation

(2017) Changmin Peng et al.   MOLECULAR CELL

A ROR1–HER3–lncRNA signalling axis modulates the Hippo–YAP pathway to regulate bone metastasis

(2017) Chunlai Li et al.   NATURE CELL BIOLOGY

RARγ Downregulation Contributes to Colorectal Tumorigenesis and Metastasis by Derepressing the Hippo–Yap Pathway

(2016) Peng-Da Guo et al.   CANCER RESEARCH

Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

(2016) Audrey W Hong et al.   EMBO REPORTS

Phosphorylation by NLK inhibits YAP‐14‐3‐3‐interactions and induces its nuclear localization

(2016) Sungho Moon et al.   EMBO REPORTS

m6A RNA methylation promotes XIST-mediated transcriptional repression

(2016) Deepak P. Patil et al.   NATURE

The lncRNA HOTAIR impacts on mesenchymal stem cellsviatriple helix formation

(2016) Marie Kalwa et al.   NUCLEIC ACIDS RESEARCH

A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells

(2016) Le Qu et al.   Nature Communications

Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis

(2015) C. Xing et al.   CANCER RESEARCH

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma

(2015) Wei Kang et al.   Molecular Cancer

The regulation and function of YAP transcription co-activator

(2014) C. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Long noncoding RNA GAS5 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

(2014) Dandan Yin et al.   MEDICAL ONCOLOGY

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

A critical role for the long non-coding RNA GAS5 in proliferation and apoptosis in non-small-cell lung cancer

(2013) Xuefei Shi et al.   MOLECULAR CARCINOGENESIS

Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction

(2013) Sheng Wang et al.   Nature Chemical Biology

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage

(2008) Dan Levy et al.   MOLECULAR CELL