DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

The nucleolus, an ally, and an enemy of cancer cells

(2018) Dariusz Stępiński   HISTOCHEMISTRY AND CELL BIOLOGY

Landscape of the complete RNA chemical modifications in the human 80S ribosome

(2018) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

(2017) Alice Galbiati et al.   Oncotarget

A reconstituted cell-free assay for the evaluation of the intrinsic activity of purified human ribosomes

(2016) Marianna Penzo et al.   Nature Protocols

A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment

(2016) T Sbarrato et al.   Cell Death & Disease

Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome

(2016) Priyanka D Abeyrathne et al.   eLife

Inhibition of Human Dyskerin as a New Approach to Target Ribosome Biogenesis

(2014) Laura Rocchi et al.   PLoS One

Regulation of snoRNAs in Cancer: Close Encounters with Interferon

(2013) Shreeram C. Nallar et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Multiscale in situ analysis of the role of dyskerin in lung cancer cells

(2012) Ignacio Fernandez-Garcia et al.   Integrative Biology

ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth

(2012) Lori S. Hart et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytoplasmic Skp2 Expression Is Associated with p-Akt1 and Predicts Poor Prognosis in Human Breast Carcinomas

(2012) Jing Liu et al.   PLoS One

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer

(2011) E S Martens-Uzunova et al.   ONCOGENE

Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis

(2010) C. Bellodi et al.   CANCER RESEARCH

Correlation of dyskerin expression with active proliferation independent of telomerase

(2010) Faizan Alawi et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Dyskerin and cancer: more than telomerase. The defect in mRNA translation helps in explaining how a proliferative defect leads to cancer

(2010) Lorenzo Montanaro   JOURNAL OF PATHOLOGY

Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing

(2010) Faizan Alawi et al.   MOLECULAR CARCINOGENESIS

DKC1 overexpression associated with prostate cancer progression

(2009) P Sieron et al.   BRITISH JOURNAL OF CANCER

What the nucleolus says to a tumour pathologist

(2009) Massimo Derenzini et al.   HISTOPATHOLOGY

Translation initiation factors are not required for Dicistroviridae IRES function in vivo

(2009) N. Deniz et al.   RNA

Nucleolus, Ribosomes, and Cancer

(2008) Lorenzo Montanaro et al.   AMERICAN JOURNAL OF PATHOLOGY