Systematic engineering of artificial metalloenzymes for new-to-nature reactions
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Systematic engineering of artificial metalloenzymes for new-to-nature reactions
Authors
Keywords
-
Journal
Science Advances
Volume 7, Issue 4, Pages eabe4208
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-01-23
DOI
10.1126/sciadv.abe4208
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Quest for Xenobiotic Enzymes: From New Enzymes for Chemistry to a Novel Chemistry of Life
- (2020) Tobias Vornholt et al. CHEMBIOCHEM
- Deep Dive into Machine Learning Models for Protein Engineering
- (2020) Yuting Xu et al. Journal of Chemical Information and Modeling
- A Mechanistic Rationale Approach Revealed the Unexpected Chemoselectivity of an Artificial Ru-Dependent Oxidase: A Dual Experimental/Theoretical Approach
- (2020) Sarah Lopez et al. ACS Catalysis
- Asymmetric δ-Lactam Synthesis with a Monomeric Streptavidin Artificial Metalloenzyme
- (2019) Isra S. Hassan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts?
- (2019) Manfred T. Reetz ACCOUNTS OF CHEMICAL RESEARCH
- Design and evolution of an enzyme with a non-canonical organocatalytic mechanism
- (2019) Ashleigh J. Burke et al. NATURE
- Machine learning-assisted directed protein evolution with combinatorial libraries
- (2019) Zachary Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Machine-learning-guided directed evolution for protein engineering
- (2019) Kevin K. Yang et al. NATURE METHODS
- Photoexcitation of flavoenzymes enables a stereoselective radical cyclization
- (2019) Kyle F. Biegasiewicz et al. SCIENCE
- Biocompatibility and therapeutic potential of glycosylated albumin artificial metalloenzymes
- (2019) Shohei Eda et al. Nature Catalysis
- Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host
- (2018) Alexander R Nödling et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Directed Evolution of Protein Catalysts
- (2018) Cathleen Zeymer et al. Annual Review of Biochemistry
- Improved Descriptors for the Quantitative Structure–Activity Relationship Modeling of Peptides and Proteins
- (2018) Mark H. Barley et al. Journal of Chemical Information and Modeling
- A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli
- (2018) Ann E Donnelly et al. Nature Chemical Biology
- Evolving artificial metalloenzymes via random mutagenesis
- (2018) Hao Yang et al. Nature Chemistry
- E. coli surface display of streptavidin for directed evolution of an allylic deallylase
- (2018) Tillmann Heinisch et al. Chemical Science
- A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium–Nitrobindin Metalloprotein
- (2018) Alexander R. Grimm et al. ACS Catalysis
- A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme
- (2018) Evan N. Mirts et al. SCIENCE
- Towards evolution of artificial metalloenzymes - A protein engineer’s perspective
- (2018) Ulrich Markel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Evolution of a highly active and enantiospecific metalloenzyme from short peptides
- (2018) Sabine Studer et al. SCIENCE
- Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene
- (2017) Antonio Tinoco et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The fourth wave of biocatalysis is approaching
- (2017) Uwe T. Bornscheuer PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid
- (2017) Ivana Drienovská et al. Chemical Science
- Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities
- (2016) Tillmann Heinisch et al. ACCOUNTS OF CHEMICAL RESEARCH
- Abiological catalysis by artificial haem proteins containing noble metals in place of iron
- (2016) Hanna M. Key et al. NATURE
- Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light
- (2016) Megan A. Emmanuel et al. NATURE
- Directed evolution of artificial metalloenzymes for in vivo metathesis
- (2016) Markus Jeschek et al. NATURE
- An artificial metalloenzyme with the kinetics of native enzymes
- (2016) P. Dydio et al. SCIENCE
- Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
- (2016) S. B. Jennifer Kan et al. SCIENCE
- Deep learning in neural networks: An overview
- (2015) Jürgen Schmidhuber NEURAL NETWORKS
- Progress towards Bioorthogonal Catalysis with Organometallic Compounds
- (2014) Timo Völker et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A De Novo Designed Metalloenzyme for the Hydration of CO2
- (2014) Virginia M. Cangelosi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Artificial metalloenzymes derived from bovine β-lactoglobulin for the asymmetric transfer hydrogenation of an aryl ketone – synthesis, characterization and catalytic activity
- (2014) Alice Chevalley et al. DALTON TRANSACTIONS
- Neutralizing the Detrimental Effect of Glutathione on Precious Metal Catalysts
- (2014) Yvonne M. Wilson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A designed supramolecular protein assembly with in vivo enzymatic activity
- (2014) Woon Ju Song et al. SCIENCE
- The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering
- (2013) Manfred T. Reetz ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biotinylated Metathesis Catalysts: Synthesis and Performance in Ring Closing Metathesis
- (2013) Anna Kajetanowicz et al. CATALYSIS LETTERS
- C(sp3)–H Bond Hydroxylation Catalyzed by Myoglobin Reconstituted with Manganese Porphycene
- (2013) Koji Oohora et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Artificial Metalloenzymes and Metallopeptide Catalysts for Organic Synthesis
- (2013) Jared C. Lewis ACS Catalysis
- Metal complex catalysis in living biological systems
- (2012) Pijus K. Sasmal et al. CHEMICAL COMMUNICATIONS
- Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation
- (2012) T. K. Hyster et al. SCIENCE
- Indole Transport across Escherichia coli Membranes
- (2011) S. Pinero-Fernandez et al. JOURNAL OF BACTERIOLOGY
- Artificial Metalloenzymes
- (2010) Fiora Rosati et al. ChemCatChem
- A Rationally Designed Fluorescence Turn-On Probe for the Gold(III) Ion
- (2010) Jung Ho Do et al. ORGANIC LETTERS
- Stability effects of mutations and protein evolvability
- (2009) Nobuhiko Tokuriki et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- X-Ray Structure and Designed Evolution of an Artificial Transfer Hydrogenase
- (2008) Marc Creus et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Addressing the Numbers Problem in Directed Evolution
- (2008) Manfred T. Reetz et al. CHEMBIOCHEM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More