Evolution of a highly active and enantiospecific metalloenzyme from short peptides

Catalytic peptide assemblies

(2018) O. Zozulia et al.   CHEMICAL SOCIETY REVIEWS

From ancestral peptides to designed proteins

(2018) Vikram Alva et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Functional Proteins from Short Peptides: Dayhoff's Hypothesis Turns 50

(2016) M. Luisa Romero Romero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Purification and characterization of a new inducible thermostable extracellular lipolytic enzyme from the thermoacidophilic archaeon Sulfolobus solfataricus P1

(2016) Yun-Ho Choi et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Installing hydrolytic activity into a completely de novo protein framework

(2016) Antony J. Burton et al.   Nature Chemistry

Assessing and maximizing data quality in macromolecular crystallography

(2015) P Andrew Karplus et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Artificial Diiron Enzymes with a De Novo Designed Four-Helix Bundle Structure

(2015) Marco Chino et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

New Tricks for Old Proteins: Single Mutations in a Nonenzymatic Protein Give Rise to Various Enzymatic Activities

(2015) Yurii S. Moroz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing Hydrolytic Zinc Metalloenzymes

(2014) Melissa L. Zastrow et al.   BIOCHEMISTRY

Protein Design: Toward Functional Metalloenzymes

(2014) Fangting Yu et al.   CHEMICAL REVIEWS

Artificial metalloenzymes for enantioselective catalysis

(2014) Jeffrey Bos et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Short peptides self-assemble to produce catalytic amyloids

(2014) Caroline M. Rufo et al.   Nature Chemistry

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

(2014) N. Preiswerk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A designed supramolecular protein assembly with in vivo enzymatic activity

(2014) Woon Ju Song et al.   SCIENCE

Computational Enzyme Design

(2013) Gert Kiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A new synthetic protocol for coumarin amino acid

(2013) Xinyi Xu et al.   Beilstein Journal of Organic Chemistry

De novo enzymes by computational design

(2013) Hajo Kries et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Precision is essential for efficient catalysis in an evolved Kemp eliminase

(2013) Rebecca Blomberg et al.   NATURE

Catalysis by a De Novo Zinc-Mediated Protein Interface: Implications for Natural Enzyme Evolution and Rational Enzyme Engineering

(2012) Bryan S. Der et al.   BIOCHEMISTRY

Computational Design of Catalytic Dyads and Oxyanion Holes for Ester Hydrolysis

(2012) Florian Richter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing a functional type 2 copper center that has nitrite reductase activity within  -helical coiled coils

(2012) M. Tegoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59

(2012) O. Khersonsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

(2011) Arren Bar-Even et al.   BIOCHEMISTRY

A Novel Cold-Active Lipase from Candida albicans: Cloning, Expression and Characterization of the Recombinant Enzyme

(2011) Dong-Ming Lan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer

(2011) Bryan S. Der et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrolytic catalysis and structural stabilization in a designed metalloprotein

(2011) Melissa L. Zastrow et al.   Nature Chemistry

Lewis Acid-Mediated Michaelis−Arbuzov Reaction at Room Temperature: A Facile Preparation of Arylmethyl/Heteroarylmethyl Phosphonates

(2011) Ganesan Gobi Rajeshwaran et al.   ORGANIC LETTERS

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Biochemical and Structural Characterization of Two Site-Directed Mutants of Staphylococcus xylosus Lipase

(2010) Deise Juliana Kolling et al.   MOLECULAR BIOTECHNOLOGY

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Design of functional metalloproteins

(2009) Yi Lu et al.   NATURE

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling

(2009) Daniel J Mandell et al.   NATURE METHODS

Metal templated design of protein interfaces

(2009) E. N. Salgado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA