Gut microbiota from patients with arteriosclerotic CSVD induces higher IL-17A production in neutrophils via activating RORγt

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

(2020) Luca Liberale et al.   EUROPEAN HEART JOURNAL

Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells

(2020) Aoife M. McGinley et al.   IMMUNITY

Commensal Bacteroidetes protect against Klebsiella pneumoniae colonization and transmission through IL-36 signalling

(2020) Richard P. Sequeira et al.   Nature Microbiology

Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke

(2020) Lijing Kang et al.   Nature Communications

Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells

(2019) Sen Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

(2019) Aniket Mishra et al.   BRAIN

Crosstalk between neutrophils and the microbiota

(2019) Dachuan Zhang et al.   BLOOD

Endogenous IL-17A mediated neutrophil infiltration by promoting chemokines expression during chlamydial lung infection

(2019) Sai Qiao et al.   MICROBIAL PATHOGENESIS

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

(2019) Maria Carolina Amezcua Vesely et al.   CELL

A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test

(2018) E.G. Kang et al.   BRITISH JOURNAL OF DERMATOLOGY

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

(2018) Alison J. Dicker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response

(2018) Giuseppe Faraco et al.   NATURE NEUROSCIENCE

Cerebral small vessel disease: from a focal to a global perspective

(2018) Annemieke ter Telgte et al.   Nature Reviews Neurology

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

(2018) Christine M. Dejea et al.   SCIENCE

Emerging Role of Immunity in Cerebral Small Vessel Disease

(2018) Ying Fu et al.   Frontiers in Immunology

Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model

(2018) Guangxin Chen et al.   EBioMedicine

Goji Berry Modulates Gut Microbiota and Alleviates Colitis in IL-10-Deficient Mice

(2018) Yifei Kang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

(2018) Luigi Ferrucci et al.   Nature Reviews Cardiology

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson’s Disease

(2018) Feng Lai et al.   NEUROCHEMICAL RESEARCH

Biodiversity across trophic levels drives multifunctionality in highly diverse forests

(2018) Andreas Schuldt et al.   Nature Communications

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)

(2018) Eleni Frangou et al.   ANNALS OF THE RHEUMATIC DISEASES

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease

(2018) Marlies P. Noz et al.   STROKE

Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

(2017) Gabriele Giacomo Schiattarella et al.   EUROPEAN HEART JOURNAL

Relationship between the neutrophil-to-lymphocyte ratio and silent cerebral small vessel disease in community-dwelling older adults. The Atahualpa Project

(2017) Aldo F. Costa et al.   Geriatrics & Gerontology International

Interleukin 17A Promotes Lymphocytes Adhesion and Induces CCL2 and CXCL1 Release from Brain Endothelial Cells

(2017) Dagmara Wojkowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction

(2017) Wolfgang Walz et al.   NEUROCHEMICAL RESEARCH

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular, glial, and lymphatic immune gateways of the central nervous system

(2016) Britta Engelhardt et al.   ACTA NEUROPATHOLOGICA

IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria

(2016) K L Flannigan et al.   Mucosal Immunology

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin

(2016) Susan H. Smith et al.   PLoS One

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Two Novel Gain-of-Function Mutations ofSTAT1Responsible for Chronic Mucocutaneous Candidiasis Disease: Impaired Production of IL-17A and IL-22, and the Presence of Anti–IL-17F Autoantibody

(2014) Yasuhiro Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

(2014) Daniel Kaiser et al.   Acta Neuropathologica Communications

Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells

(2013) Hsiao-yin Yang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

CNS-Targeted Production of IL-17A Induces Glial Activation, Microvascular Pathology and Enhances the Neuroinflammatory Response to Systemic Endotoxemia

(2013) Julian Zimmermann et al.   PLoS One

N2 Neutrophils, Novel Players in Brain Inflammation After Stroke

(2013) María Isabel Cuartero et al.   STROKE

Compression-only Cardiopulmonary Resuscitation Improves Survival

(2011) Gordon A. Ewy et al.   AMERICAN JOURNAL OF MEDICINE

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Enlarged Perivascular Spaces on MRI Are a Feature of Cerebral Small Vessel Disease

(2010) Fergus N. Doubal et al.   STROKE