Immunogenic cell death-inducing chemotherapeutic nanoformulations potentiate combination chemoimmunotherapy

Inhibition of Immunosuppressive Tumors by Polymer‐Assisted Inductions of Immunogenic Cell Death and Multivalent PD‐L1 Crosslinking

(2020) Lian Li et al.   ADVANCED FUNCTIONAL MATERIALS

Codelivery of Anti‐PD‐1 Antibody and Paclitaxel with Matrix Metalloproteinase and pH Dual‐Sensitive Micelles for Enhanced Tumor Chemoimmunotherapy

(2020) Zhenwei Su et al.   Small

Reshaping Tumor Immune Microenvironment through Acidity-Responsive Nanoparticles Featured with CRISPR/Cas9-Mediated Programmed Death-Ligand 1 Attenuation and Chemotherapeutics-Induced Immunogenic Cell Death

(2020) Kun Tu et al.   ACS Applied Materials & Interfaces

Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma

(2020) Zhuo Yu et al.   ACS Nano

Macrophage-mimic shape changeable nanomedicine retained in tumor for multimodal therapy of breast cancer

(2020) Rui Liu et al.   JOURNAL OF CONTROLLED RELEASE

Co‐Delivery of Paclitaxel and Interleukin‐12 Regulating Tumor Microenvironment for Cancer Immunochemotherapy

(2020) Qian Hu et al.   Advanced Healthcare Materials

Codelivered Chemotherapeutic Doxorubicin via a Dual-Functional Immunostimulatory Polymeric Prodrug for Breast Cancer Immunochemotherapy

(2020) Yang Lan et al.   ACS Applied Materials & Interfaces

Tackling autoimmunity with nanomedicines

(2020) Xiangru Feng et al.   Nanomedicine

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

(2020) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Polypeptide nanoformulation-induced immunogenic cell death and remission of immunosuppression for enhanced chemoimmunotherapy

(2020) Xiangru Feng et al.   Science Bulletin

Role of nanoparticle-mediated immunogenic cell death in cancer immunotherapy

(2020) Yajie Sun et al.   Asian Journal of Pharmaceutical Sciences

Multifunctional polymeric micelle-based chemo-immunotherapy with immune checkpoint blockade for efficient treatment of orthotopic and metastatic breast cancer

(2019) Jiaojie Wei et al.   Acta Pharmaceutica Sinica B

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Combining activatable nanodelivery with immunotherapy in a murine breast cancer model

(2019) Azadeh Kheirolomoom et al.   JOURNAL OF CONTROLLED RELEASE

Nanoenabled Reversal of IDO1-Mediated Immunosuppression Synergizes with Immunogenic Chemotherapy for Improved Cancer Therapy

(2019) Hua Huang et al.   NANO LETTERS

Immunomodulatory Nanosystems

(2019) Xiangru Feng et al.   Advanced Science

Survey of Clinical Translation of Cancer Nanomedicines—Lessons Learned from Successes and Failures

(2019) Hongliang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multiantigenic Nanoformulations Activate Anticancer Immunity Depending on Size

(2019) Shengxian Li et al.   ADVANCED FUNCTIONAL MATERIALS

Synergistical chemotherapy and cancer immunotherapy using dual drug-delivering and immunopotentiating mesoporous silica

(2019) Xia Li et al.   Applied Materials Today

Targeted pH-responsive polyion complex micelle for controlled intracellular drug delivery

(2019) Pan Zheng et al.   CHINESE CHEMICAL LETTERS

Reprogramming the T cell response to cancer by simultaneous, nanoparticle-mediated PD-L1 inhibition and immunogenic cell death

(2019) Cao Dai Phung et al.   JOURNAL OF CONTROLLED RELEASE

Combining Doxorubicin-Loaded PEGylated Poly(Lactide-co-glycolide) Nanoparticles with Checkpoint Inhibition Safely Enhances Therapeutic Efficacy in a Melanoma Model

(2019) Khanidtha Chitphet et al.   ACS Biomaterials-Science & Engineering

Biointerface engineering nanoplatforms for cancer-targeted drug delivery

(2019) Huaiyu Zhang et al.   Asian Journal of Pharmaceutical Sciences

Enhanced Tumor Retention Effect by Click Chemistry for Improved Cancer Immunochemotherapy

(2018) Ling Mei et al.   ACS Applied Materials & Interfaces

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immunogenic chemotherapy: Dose and schedule dependence and combination with immunotherapy

(2018) Junjie Wu et al.   CANCER LETTERS

Co-delivery of Doxorubicin and Interferon-gamma by Thermosensitive Nanoparticles for Cancer Immunochemotherapy

(2018) Yijia Yin et al.   MOLECULAR PHARMACEUTICS

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Elimination of established tumors with nanodisc-based combination chemoimmunotherapy

(2018) Rui Kuai et al.   Science Advances

Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

(2018) Bing Feng et al.   ADVANCED MATERIALS

Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies

(2018) Qiang Wang et al.   CANCER LETTERS

Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway

(2018) Jianqin Lu et al.   ACS Nano

An emerging role for nanomaterials in increasing immunogenicity of cancer cell death

(2018) Tatiana Mishchenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

(2018) Melody Smith et al.   OncoImmunology

The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer

(2017) Hanke L. Matlung et al.   IMMUNOLOGICAL REVIEWS

A STING-activating nanovaccine for cancer immunotherapy

(2017) Min Luo et al.   Nature Nanotechnology

Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies

(2017) David J. Byun et al.   Nature Reviews Endocrinology

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

(2017) Guangbao Yang et al.   Nature Communications

PD-1 expression on tumor-specific T cells: Friend or foe for immunotherapy?

(2017) Sylvain Simon et al.   OncoImmunology

Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours

(2017) Suping Li et al.   Nature Biomedical Engineering

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy

(2016) Xiao Zhao et al.   BIOMATERIALS

Clinical advances of nanocarrier-based cancer therapy and diagnostics

(2016) Edurne Luque-Michel et al.   Expert Opinion on Drug Delivery

Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

(2016) Christina Pfirschke et al.   IMMUNITY

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

(2016) Vassiliki A. Boussiotis   NEW ENGLAND JOURNAL OF MEDICINE

An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

(2016) Yichao Chen et al.   Nature Communications

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

(2016) Shohei Koyama et al.   Nature Communications

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment

(2015) Jinqiang Wang et al.   ACS Nano

Improving drug delivery to solid tumors: Priming the tumor microenvironment

(2015) Iftikhar Ali Khawar et al.   JOURNAL OF CONTROLLED RELEASE

CD47 blockade as another immune checkpoint therapy for cancer

(2015) Robert H Vonderheide   NATURE MEDICINE

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models

(2015) Jayanta Bhattacharyya et al.   Nature Communications

PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer

(2014) H. Wimberly et al.   Cancer Immunology Research

Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry

(2013) Hatem Soliman et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours

(2011) R Plummer et al.   BRITISH JOURNAL OF CANCER

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Cytokines in Cancer Immunotherapy

(2011) Sylvia Lee et al.   Cancers

Polymeric nanomedicine for cancer therapy

(2007) Jae Hyung Park et al.   PROGRESS IN POLYMER SCIENCE