Effects of Non-Coding RNA on Regulatory T Cells and Implications for Treatment of Immunological Diseases

MicroRNA-181a and microRNA-155 are involved in the regulation of the differentiation and function of regulatory T cells in allergic rhinitis children

(2019) Qingxiang Zeng et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction

(2019) Lisa Schmidleithner et al.   IMMUNITY

LncRNA SNHG1 regulates the differentiation of Treg cells and affects the immune escape of breast cancer via regulating miR-448/IDO

(2018) Xinhong Pei et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation

(2018) Ruifang Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes

(2018) Isabelle Serr et al.   Science Translational Medicine

Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21

(2018) Shengwei Jin et al.   ANNALS OF THE RHEUMATIC DISEASES

Excessive expression of miR-27 impairs Treg-mediated immunological tolerance

(2017) Leilani O. Cruz et al.   JOURNAL OF CLINICAL INVESTIGATION

Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity

(2017) David Zemmour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression

(2017) Guido Sebastiani et al.   Scientific Reports

The Inflammatory Response in Psoriasis: a Comprehensive Review

(2016) Yaxiong Deng et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

miR-23∼27∼24 clusters control effector T cell differentiation and function

(2016) Sunglim Cho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

LncRNA HULC affects the differentiation of Treg in HBV-related liver cirrhosis

(2015) Jie Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

(2015) Wen Pan et al.   Nature Communications

MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3

(2015) Lingyun Zhang et al.   Nature Communications

MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression

(2015) Dan Li et al.   Scientific Reports

FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells

(2014) X Liu et al.   BONE MARROW TRANSPLANTATION

Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth

(2014) Yuan Yin et al.   CELL RESEARCH

MicroRNA-126 regulates the induction and function of CD4+Foxp3+regulatory T cells through PI3K/AKT pathway

(2013) Andong Qin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

microRNA-17-92 Regulates IL-10 Production by Regulatory T Cells and Control of Experimental Autoimmune Encephalomyelitis

(2013) D. de Kouchkovsky et al.   JOURNAL OF IMMUNOLOGY

MicroRNA 10a Marks Regulatory T Cells

(2012) Lukas T. Jeker et al.   PLoS One

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

(2011) S. Jiang et al.   BLOOD

Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity

(2011) Mireia Guerau-de-Arellano et al.   BRAIN

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease

(2010) S. Jia et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathogenesis and management of Kawasaki disease

(2010) Anne H Rowley et al.   Expert Review of Anti-Infective Therapy

Regulation of MicroRNA Expression and Abundance during Lymphopoiesis

(2010) Stefan Kuchen et al.   IMMUNITY

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.

(2010) Matthias Merkenschlager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

(2009) Redouane Rouas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

(2009) S. Kohlhaas et al.   JOURNAL OF IMMUNOLOGY

miR-142-3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA

(2008) Bo Huang et al.   EMBO REPORTS

The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers

(2008) Chunguang Guo et al.   GENES CHROMOSOMES & CANCER

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE