In Vivo Positron Emission Tomography Imaging of Adenosine A2A Receptors

The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson’s disease

(2020) Jiang-Fan Chen et al.   Purinergic Signalling

PET Imaging of Adenosine Receptors in Diseases

(2019) Jindian Li et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Role of purines in regulation of metabolic reprogramming

(2019) Zhenwei Tang et al.   Purinergic Signalling

Regulation of human brown adipose tissue by adenosine and A2A receptors – studies with [15O]H2O and [11C]TMSX PET/CT

(2018) Minna Lahesmaa et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Occupancy of adenosine A2A receptors by istradefylline in patients with Parkinson's disease using 11C-preladenant PET

(2018) Kenji Ishibashi et al.   NEUROPHARMACOLOGY

Initial Evaluation of an Adenosine A 2A Receptor Ligand, 11 C-Preladenant, in Healthy Human Subjects

(2017) Muneyuki Sakata et al.   JOURNAL OF NUCLEAR MEDICINE

In Vivo Evaluation of11C-Preladenant for PET Imaging of Adenosine A2AReceptors in the Conscious Monkey

(2017) Xiaoyun Zhou et al.   JOURNAL OF NUCLEAR MEDICINE

The Adenosinergic System as a Therapeutic Target in the Vasculature: New Ligands and Challenges

(2017) Joana Sousa et al.   MOLECULES

In vivo evaluation of [11C]preladenant positron emission tomography for quantification of adenosine A2A receptors in the rat brain

(2016) Xiaoyun Zhou et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Preclinical Evaluation and Quantification of 18 F-Fluoroethyl and 18 F-Fluoropropyl Analogs of SCH442416 as Radioligands for PET Imaging of the Adenosine A 2A Receptor in Rat Brain

(2016) Shivashankar Khanapur et al.   JOURNAL OF NUCLEAR MEDICINE

Radiation Dosimetry of a Novel Adenosine A2A Receptor Radioligand [11C]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats

(2016) Xiaoyun Zhou et al.   MOLECULAR IMAGING AND BIOLOGY

Purines in neurodegeneration and neuroregeneration

(2016) Peter Illes et al.   NEUROPHARMACOLOGY

Characterization in Humans of 18F-MNI-444, a PET Radiotracer for Brain Adenosine 2A Receptors

(2015) O. Barret et al.   JOURNAL OF NUCLEAR MEDICINE

Development of PET radiopharmaceuticals and their clinical applications at the Positron Medical Center

(2015) Kiichi Ishiwata et al.   Geriatrics & Gerontology International

Automated Reference Region Extraction and Population-Based Input Function for Brain [11C]TMSX PET Image Analyses

(2014) Eero Rissanen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synthesis and Preclinical Evaluation of 2-(2-Furanyl)-7-[2-[4-[4-(2-[11C]methoxyethoxy)phenyl]-1-piperazinyl]ethyl]7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine-5-amine ([11C]Preladenant) as a PET Tracer for the Imaging of Cerebral Adenosine A2A Receptors

(2014) Xiaoyun Zhou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of [18F]-Labeled Pyrazolo[4,3-e]-1,2,4- triazolo[1,5-c]pyrimidine (SCH442416) Analogs for the Imaging of Cerebral Adenosine A2A Receptors with Positron Emission Tomography

(2014) Shivashankar Khanapur et al.   JOURNAL OF MEDICINAL CHEMISTRY

Adenosine 2A Receptor Occupancy by Tozadenant and Preladenant in Rhesus Monkeys

(2014) O. Barret et al.   JOURNAL OF NUCLEAR MEDICINE

Adenosine A2A Receptor Antagonists as Positron Emission Tomography (PET) Tracers

(2013) S. Khanapur et al.   CURRENT MEDICINAL CHEMISTRY

Adenosine A2A Receptors in Secondary Progressive Multiple Sclerosis: A [11C]TMSX Brain PET Study

(2013) Eero Rissanen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Kinetic Modeling, Test-Retest, and Dosimetry of 123I-MNI-420 in Humans

(2013) A. A. S. Tavares et al.   JOURNAL OF NUCLEAR MEDICINE

Adenosine in the Inflamed Gut: A Janus Faced Compound

(2011) A. B. Estrela et al.   CURRENT MEDICINAL CHEMISTRY

Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease

(2011) A. F. Ramlackhansingh et al.   NEUROLOGY

Striatal adenosine A2A receptor-mediated positron emission tomographic imaging in 6-hydroxydopamine-lesioned rats using [18F]-MRS5425

(2011) Abesh Kumar Bhattacharjee et al.   NUCLEAR MEDICINE AND BIOLOGY

An Open-Label, Positron Emission Tomography Study to Assess Adenosine A2A Brain Receptor Occupancy of Vipadenant (BIIB014) at Steady-State Levels in Healthy Male Volunteers

(2010) David J. Brooks et al.   CLINICAL NEUROPHARMACOLOGY