Fisetin Regulates Gut Microbiota and Exerts Neuroprotective Effect on Mouse Model of Parkinson’s Disease

A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice

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Lactobacillus plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse models of Parkinson’s disease

(2020) Jian-Fu Liao et al.   BRAIN BEHAVIOR AND IMMUNITY

Genistein Inhibits Aβ25–35-Induced Neuronal Death with Changes in the Electrophysiological Properties of Voltage-Gated Sodium and Potassium Channels

(2019) Yu-xiang Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Roles of Shiga Toxins in Immunopathology

(2019) Moo-Seung Lee et al.   Toxins

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

(2019) Sunil Srivastav et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression

(2019) Velma T.E. Aho et al.   EBioMedicine

Antibiotic-induced microbiome depletion protects against MPTP-induced dopaminergic neurotoxicity in the brain

(2019) Yaoyu Pu et al.   Aging-US

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson’s disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway

(2018) Meng-Fei Sun et al.   BRAIN BEHAVIOR AND IMMUNITY

The role of functional amyloids in bacterial virulence

(2018) Nani Van Gerven et al.   JOURNAL OF MOLECULAR BIOLOGY

Gut microbiota in patients with Parkinson's disease in southern China

(2018) Aiqun Lin et al.   PARKINSONISM & RELATED DISORDERS

Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell

(2018) Yibing Si et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

(2017) Erin M. Hill-Burns et al.   MOVEMENT DISORDERS

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Non-motor features of Parkinson disease

(2017) Anthony H.V. Schapira et al.   NATURE REVIEWS NEUROSCIENCE

Oral and nasal microbiota in Parkinson's disease

(2017) Pedro A.B. Pereira et al.   PARKINSONISM & RELATED DISORDERS

Structural changes of gut microbiota in Parkinson’s disease and its correlation with clinical features

(2017) Wei Li et al.   Science China-Life Sciences

Protective effects of fisetin and other berry flavonoids in Parkinson's disease

(2017) Pamela Maher   Food & Function

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

(2017) T. Harach et al.   Scientific Reports

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma

(2016) L. T. Stiemsma et al.   CLINICAL SCIENCE

α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology

(2016) Josefine R. Christiansen et al.   Journal of Neuroinflammation

Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice

(2016) Ashfaq Ahmad et al.   MOLECULAR NEUROBIOLOGY

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

(2016) Patrick P. Michel et al.   NEURON

Animal behavioral assessments in current research of Parkinson’s disease

(2016) Tetsuya Asakawa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

(2016) Marcus M. Unger et al.   PARKINSONISM & RELATED DISORDERS

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

(2016) Shu G. Chen et al.   Scientific Reports

Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells

(2015) Eiman Mukhtar et al.   CANCER LETTERS

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Gastrointestinal dysfunction in Parkinson's disease

(2015) Alfonso Fasano et al.   LANCET NEUROLOGY

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

New insight into the molecular control of bacterial functional amyloids

(2015) Jonathan D. Taylor et al.   Frontiers in Cellular and Infection Microbiology

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Gut microbiota dysbiosis and bacterial community assembly associated with cholesterol gallstones in large-scale study

(2013) Tao Wu et al.   BMC GENOMICS

Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management

(2012) Vaqar Mustafa Adhami et al.   BIOCHEMICAL PHARMACOLOGY

In-feed antibiotic effects on the swine intestinal microbiome

(2012) T. Looft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noninvasive in vivo assessment of muscle impairment in the mdx mouse model – A comparison of two common wire hanging methods with two different results

(2011) Silvan M. Klein et al.   JOURNAL OF NEUROSCIENCE METHODS

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS