Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab

(2020) Lionel Rougé et al.   SCIENCE

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs

(2020) Rajagopal Murugan et al.   NATURE MEDICINE

RTS,S malaria vaccine pilots in three African countries

(2019) Paul Adepoju   LANCET

Elucidating Mechanisms of Drug-Resistant Plasmodium falciparum

(2019) Leila S. Ross et al.   Cell Host & Microbe

Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy

(2019) Carlota Dobaño et al.   Nature Communications

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens

(2019) Joseph J. Illingworth et al.   Frontiers in Immunology

Development of B Cell Memory in Malaria

(2019) Ann Ly et al.   Frontiers in Immunology

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein

(2019) Tossapol Pholcharee et al.   JOURNAL OF MOLECULAR BIOLOGY

Malaria Elimination: Time to Target All Species

(2018) Andrew A. Lover et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Malaria Vaccines: Recent Advances and New Horizons

(2018) Simon J. Draper et al.   Cell Host & Microbe

Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies

(2018) Stephen W. Scally et al.   IMMUNITY

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

(2018) Joshua Tan et al.   NATURE MEDICINE

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

(2018) Neville K Kisalu et al.   NATURE MEDICINE

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

(2018) Katharina Imkeller et al.   SCIENCE

Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment

(2018) Robert Bernedo-Navarro et al.   Toxins

Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

(2018) Ellie Sherrard-Smith et al.   eLife

Correlating efficacy and immunogenicity in malaria vaccine trials

(2018) Matthew B.B. McCall et al.   SEMINARS IN IMMUNOLOGY

Rodent malaria models: insights into human disease and parasite biology

(2018) Mariana De Niz et al.   CURRENT OPINION IN MICROBIOLOGY

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

(2018) David Oyen et al.   Science Advances

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies

(2017) Gianna Triller et al.   IMMUNITY

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

(2017) Stephen W. Scally et al.   JOURNAL OF EXPERIMENTAL MEDICINE

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Structural basis for antibody recognition of the NANP repeats inPlasmodium falciparumcircumsporozoite protein

(2017) David Oyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

The liquid structure of elastin

(2017) Sarah Rauscher et al.   eLife

Force Spectroscopy of thePlasmodium falciparumVaccine Candidate Circumsporozoite Protein Suggests a Mechanically Pliable Repeat Region

(2016) Aditya Prasad Patra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

(2016) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network

(2015) Liwang Cui et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains

(2015) Raul Herrera et al.   INFECTION AND IMMUNITY

Alignment of cryo-EM movies of individual particles by optimization of image translations

(2015) John L. Rubinstein et al.   JOURNAL OF STRUCTURAL BIOLOGY

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Advances in molecular genetic systems in malaria

(2015) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

Large screen approaches to identify novel malaria vaccine candidates

(2015) D. Huw Davies et al.   VACCINE

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure

(2015) Richard T. Sullivan et al.   PLoS Pathogens

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

(2015) Silvia Portugal et al.   eLife

The Plasmodium bottleneck: malaria parasite losses in the mosquito vector

(2014) Ryan C Smith et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Fabrication of carbon films with ∼500nm holes for cryo-EM with a direct detector device

(2013) Chelsea R. Marr et al.   JOURNAL OF STRUCTURAL BIOLOGY

Repeat-Enriched Proteins Are Related to Host Cell Invasion and Immune Evasion in Parasitic Protozoa

(2013) T.A.O. Mendes et al.   MOLECULAR BIOLOGY AND EVOLUTION

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity

(2012) Satish Mishra et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivax

(2012) Stella M Chenet et al.   MALARIA JOURNAL

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Systematic Validation of Protein Force Fields against Experimental Data

(2012) Kresten Lindorff-Larsen et al.   PLoS One

How Robust Are Protein Folding Simulations with Respect to Force Field Parameterization?

(2011) Stefano Piana et al.   BIOPHYSICAL JOURNAL

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition

(2011) David S. Booth et al.   Jove-Journal of Visualized Experiments

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Plasmodium immunomics

(2010) Denise L. Doolan   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Variable Numbers of Tandem Repeats in Plasmodium falciparum Genes

(2010) John C. Tan et al.   JOURNAL OF MOLECULAR EVOLUTION

Protein Simulations with an Optimized Water Model: Cooperative Helix Formation and Temperature-Induced Unfolded State Collapse

(2010) Robert B. Best et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of thePlasmodium falciparumCircumsporozoite Protein, a Leading Malaria Vaccine Candidate

(2009) Matthew L. Plassmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Malaria Control, Elimination, and Eradication: The Role of the Evolving Biomedical Research Agenda

(2009) B. Fenton Hall et al.   JOURNAL OF INFECTIOUS DISEASES

Optimized Molecular Dynamics Force Fields Applied to the Helix−Coil Transition of Polypeptides

(2009) Robert B. Best et al.   JOURNAL OF PHYSICAL CHEMISTRY B

An Improved Cryogen for Plunge Freezing

(2008) William F. Tivol et al.   MICROSCOPY AND MICROANALYSIS

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation