Small molecule cognitive enhancer reverses age-related memory decline in mice
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Small molecule cognitive enhancer reverses age-related memory decline in mice
Authors
Keywords
-
Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-12-01
DOI
10.7554/elife.62048
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning
- (2020) K.B. Casaletto et al. BRAIN BEHAVIOR AND IMMUNITY
- Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain
- (2020) Alana M. Horowitz et al. SCIENCE
- A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease
- (2020) Emily J. Davis et al. Science Translational Medicine
- Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis
- (2019) Umut I. Onat et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
- (2019) Hanadie Yousef et al. NATURE MEDICINE
- Cognitive aging is not created equally: differentiating unique cognitive phenotypes in “normal” adults
- (2019) Kaitlin B. Casaletto et al. NEUROBIOLOGY OF AGING
- Single-cell analysis reveals T cell infiltration in old neurogenic niches
- (2019) Ben W. Dulken et al. NATURE
- Pharmacological targeting of the unfolded protein response for disease intervention
- (2019) Claudio Hetz et al. Nature Chemical Biology
- T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses
- (2019) Charise Garber et al. NATURE NEUROSCIENCE
- Integrated Stress Response Inhibitor Reverses Sex-Dependent Behavioral and Cell-Specific Deficits after Mild Repetitive Head Trauma
- (2019) Karen Krukowski et al. JOURNAL OF NEUROTRAUMA
- Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α
- (2019) Kevin Klann et al. MOLECULAR CELL
- High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
- (2018) Dunja Mrdjen et al. IMMUNITY
- Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain
- (2018) Austin Chou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Peripheral T Cells as a Biomarker for Oxygen-Ion-Radiation-Induced Social Impairments
- (2018) Karen Krukowski et al. RADIATION RESEARCH
- Role of eIF2α Kinases in Translational Control and Adaptation to Cellular Stress
- (2018) Ronald C. Wek Cold Spring Harbor Perspectives in Biology
- Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
- (2018) Adam C. Frank et al. Nature Communications
- Female mice are protected from space radiation-induced maladaptive responses
- (2018) Karen Krukowski et al. BRAIN BEHAVIOR AND IMMUNITY
- Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
- (2018) Giovanni Di Liberto et al. CELL
- Loss of thin spines and small synapses contributes to defective hippocampal function in aged mice
- (2018) Benke Xu et al. NEUROBIOLOGY OF AGING
- Female XX sex chromosomes increase survival and extend lifespan in aging mice
- (2018) Emily J. Davis et al. AGING CELL
- Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits
- (2018) Karen Krukowski et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring
- (2018) Roberta Cagnetta et al. MOLECULAR CELL
- M(en)TORship lessons on life and death by the integrated stress response
- (2018) Antonis E. Koromilas BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Energy Metabolism and Ageing in the Mouse: A Mini-Review
- (2017) Vian Azzu et al. GERONTOLOGY
- Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
- (2017) Joseph M. Castellano et al. NATURE
- Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury
- (2017) Austin Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
- (2017) Aleksandra Deczkowska et al. Nature Communications
- CA1 pyramidal cells have diverse biophysical properties, affected by development, experience, and aging
- (2017) Erin C. McKiernan et al. PeerJ
- Translational control by 5'-untranslated regions of eukaryotic mRNAs
- (2016) A. G. Hinnebusch et al. SCIENCE
- mTORC2 Balances AKT Activation and eIF2 Serine 51 Phosphorylation to Promote Survival under Stress
- (2015) C. Tenkerian et al. MOLECULAR CANCER RESEARCH
- β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis
- (2015) Lucas K Smith et al. NATURE MEDICINE
- Specific Downregulation of Hippocampal ATF4 Reveals a Necessary Role in Synaptic Plasticity and Memory
- (2015) Silvia Pasini et al. Cell Reports
- Dissecting mechanisms of brain aging by studying the intrinsic excitability of neurons
- (2015) Valerio Rizzo et al. Frontiers in Aging Neuroscience
- Age, Sex, andAPOEε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span
- (2015) Clifford R. Jack et al. JAMA Neurology
- Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
- (2014) Saul A Villeda et al. NATURE MEDICINE
- Aging-induced type I interferon response at the choroid plexus negatively affects brain function
- (2014) K. Baruch et al. SCIENCE
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- RNA-binding proteins involved in RNA localization and their implications in neuronal diseases
- (2012) Marco Tolino et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Evidence for Reduced Experience-Dependent Dendritic Spine Plasticity in the Aging Prefrontal Cortex
- (2011) E. B. Bloss et al. JOURNAL OF NEUROSCIENCE
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Neural protein synthesis during aging: effects on plasticity and memory
- (2010) Schimanski Frontiers in Aging Neuroscience
- Learning and aging related changes in intrinsic neuronal excitability
- (2010) Oh Frontiers in Aging Neuroscience
- Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
- (2009) Evan T. Powers et al. Annual Review of Biochemistry
- Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
- (2009) Nahum Sonenberg et al. CELL
- Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice
- (2009) C. C. Kaczorowski et al. LEARNING & MEMORY
- Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase A
- (2009) M. M. Oh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Principles of Long-Term Dynamics of Dendritic Spines
- (2008) N. Yasumatsu et al. JOURNAL OF NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started