Cell Death Signaling Pathway Induced by Cholix Toxin, a Cytotoxin and eEF2 ADP-Ribosyltransferase Produced by Vibrio cholerae

Global emergence of environmental non‐O1 / O139 Vibrio cholerae infections linked with climate change: a neglected research field?

(2020) Luigi Vezzulli et al.   ENVIRONMENTAL MICROBIOLOGY

Non-O1, Non-O139 Vibrio cholerae (NOVC) Bacteremia: Case Report and Literature Review, 2015–2019

(2020) Xiaohui Zhang et al.   Infection and Drug Resistance

Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species

(2020) Geoffrey Masuyer   Toxins

Phenotypic and Genotypic Properties of Vibrio cholerae non-O1, non-O139 Isolates Recovered from Domestic Ducks in Germany

(2020) Nicola Hirsch et al.   Microorganisms

Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process

(2019) Jowita Nowakowska-Gołacka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cholix toxin, an eukaryotic elongation factor 2 ADP‐ribosyltransferase, interacts with Prohibitins and induces apoptosis with mitochondrial dysfunction in human hepatocytes

(2019) Kinnosuke Yahiro et al.   CELLULAR MICROBIOLOGY

Environmental and Clinical Strains of Vibrio cholerae Non-O1, Non-O139 From Germany Possess Similar Virulence Gene Profiles

(2019) Keike Schwartz et al.   Frontiers in Microbiology

T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- and polymicrobial infections

(2019) Ana Fernández-Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Occurrence and Abundance of Pathogenic Vibrio Species in Raw Oysters at Retail Seafood Markets in Northwestern Mexico

(2019) CLAUDIA VILLICAÑA et al.   JOURNAL OF FOOD PROTECTION

Potentially human pathogenic Vibrio spp. in a coastal transect: Occurrence and multiple virulence factors

(2019) Sidika Hackbusch et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress

(2018) Corey J. Anderson et al.   JOURNAL OF NEUROCHEMISTRY

COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity

(2018) Yiting Jia et al.   Cell Death & Disease

Transmission and Toxigenic Potential of Vibrio cholerae in Hilsha Fish (Tenualosa ilisha) for Human Consumption in Bangladesh

(2018) Zenat Z. Hossain et al.   Frontiers in Microbiology

Accessory Toxins of Vibrio Pathogens and Their Role in Epithelial Disruption During Infection

(2018) Diliana Pérez-Reytor et al.   Frontiers in Microbiology

Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes

(2017) Chongshu Jian et al.   JOURNAL OF CELL SCIENCE

Cholera

(2017) John D Clemens et al.   LANCET

IslandViewer 4: expanded prediction of genomic islands for larger-scale datasets

(2017) Claire Bertelli et al.   NUCLEIC ACIDS RESEARCH

Vibrio cholerae Cholix toxin-induced HepG2 cell death is enhanced by tumor necrosis factor-alpha through ROS and intracellular signal-regulated kinases

(2017) Kohei Ogura et al.   TOXICOLOGICAL SCIENCES

Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming

(2017) Fazle Rabbi Chowdhury et al.   Annals of Clinical Microbiology and Antimicrobials

Fish as Hosts of Vibrio cholerae

(2017) Malka Halpern et al.   Frontiers in Microbiology

Multifaceted role of prohibitin in cell survival and apoptosis

(2015) Ya-Ting Peng et al.   APOPTOSIS

Pocket analysis of the full-length cholix toxin. An assessment of the structure–dynamics of theapocatalytic domain

(2015) Miguel R. Lugo et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

A comparative structure-function analysis of active-site inhibitors ofVibrio choleraecholix toxin

(2015) Miguel R. Lugo et al.   JOURNAL OF MOLECULAR RECOGNITION

The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family

(2015) Miguel Lugo et al.   Toxins

Pseudomonas Exotoxin A: optimized by evolution for effective killing

(2015) Marta Michalska et al.   Frontiers in Microbiology

Prevalence of Vibrio cholerae O1 El Tor variant in a cholera-endemic zone of Kenya

(2014) S. M. Saidi et al.   JOURNAL OF MEDICAL MICROBIOLOGY

The biosynthesis and biological function of diphthamide

(2013) Xiaoyang Su et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genetic and phenotypic analysis of Vibrio cholerae non-O1, non-O139 isolated from German and Austrian patients

(2013) F. Schirmeister et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network

(2013) Shanow Uthman et al.   PLoS Genetics

Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial Cells

(2012) Wenjian Wang et al.   Cell Metabolism

Novel Cholix Toxin Variants, ADP-Ribosylating Toxins in Vibrio cholerae Non-O1/Non-O139 Strains, and Their Pathogenicity

(2012) Sharda Prasad Awasthi et al.   INFECTION AND IMMUNITY

The 1.8 Å Cholix Toxin Crystal Structure in Complex with NAD+and Evidence for a New Kinetic Model

(2012) Robert J. Fieldhouse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Genetic Diversity of O-Antigen Biosynthesis Regions inVibrio cholerae

(2011) Antonina Aydanian et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterization of Cholix Toxin-induced Apoptosis in HeLa Cells

(2011) Kohei Ogura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins

(2010) Zachari Turgeon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Non-O1, non-O139 Vibrio cholerae bacteraemia in a cirrhotic patient

(2010) O. Petsaris et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Vibrio cholerae Hemolysin Is Required for Lethality, Developmental Delay, and Intestinal Vacuolation in Caenorhabditis elegans

(2010) Hediye Nese Cinar et al.   PLoS One

Diversity and distribution of cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae

(2010) Alexandra E. Purdy et al.   Environmental Microbiology Reports

Processing of Pseudomonas aeruginosa Exotoxin A Is Dispensable for Cell Intoxication

(2009) J. Morlon-Guyot et al.   INFECTION AND IMMUNITY

Prohibitin and mitochondrial biology

(2009) Marta Artal-Sanz et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The role of the diphthamide-containing loop within eukaryotic elongation factor 2 in ADP-ribosylation byPseudomonas aeruginosaexotoxin A

(2008) Yong Zhang et al.   BIOCHEMICAL JOURNAL

Severe Diarrhea Caused by Cholera Toxin–ProducingVibrio choleraeSerogroup O75 Infections Acquired in the Southeastern United States

(2008) Melissa Tobin‐D’Angelo et al.   CLINICAL INFECTIOUS DISEASES

Cholix Toxin, a Novel ADP-ribosylating Factor fromVibrio cholerae

(2008) René Jørgensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

(2008) Michael Schleicher et al.   JOURNAL OF CELL BIOLOGY