The 1.8 Å Cholix Toxin Crystal Structure in Complex with NAD+and Evidence for a New Kinetic Model

Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939

(2012) Christina A. Kirby et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Therapeutic potential of anticancer immunotoxins

(2011) Swati Choudhary et al.   DRUG DISCOVERY TODAY

Linking Distinct Conformations of Nicotinamide Adenine Dinucleotide with Protein Fold/Function

(2011) Gopi Kuppuraj et al.   JOURNAL OF PHYSICAL CHEMISTRY B

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins

(2010) Zachari Turgeon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A role for flexible loops in enzyme catalysis

(2010) M Merced Malabanan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

LigAlign: Flexible ligand-based active site alignment and analysis

(2010) Abraham Heifets et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

From cosubstrate similarity to inhibitor diversity—inhibitors of ADP-ribosyltransferases from kinase inhibitor screening

(2010) Benjamin Maurer et al.   Molecular BioSystems

Diversity and distribution of cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae

(2010) Alexandra E. Purdy et al.   Environmental Microbiology Reports

Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

(2009) Robert Sarnovsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins

(2009) Zachari Turgeon et al.   FEMS MICROBIOLOGY LETTERS

Processing of Pseudomonas aeruginosa Exotoxin A Is Dispensable for Cell Intoxication

(2009) J. Morlon-Guyot et al.   INFECTION AND IMMUNITY

Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa fromClostridium difficile

(2009) Amit Sundriyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developing novel approaches to improve binding energy estimation and virtual screening: a PARP case study

(2009) Fedor N. Novikov et al.   JOURNAL OF MOLECULAR MODELING

Molecular Mechanisms of the Cytotoxicity of ADP-Ribosylating Toxins

(2008) Qing Deng et al.   Annual Review of Microbiology

Putative Virulence Traits and Pathogenicity of Vibrio cholerae Non-O1, Non-O139 Isolates from Surface Waters in Kolkata, India

(2008) P. K. Bag et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The nature and character of the transition state for the ADP-ribosyltransferase reaction

(2008) René Jørgensen et al.   EMBO REPORTS

Cholix Toxin, a Novel ADP-ribosylating Factor fromVibrio cholerae

(2008) René Jørgensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY