Multi-modal Single-Cell Analysis Reveals Brain Immune Landscape Plasticity during Aging and Gut Microbiota Dysbiosis

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

(2020)   NATURE

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

(2019) Marta Joana Costa Jordão et al.   SCIENCE

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis

(2019) Qianquan Ma et al.   Journal of Neuroinflammation

Pre-existing commensal dysbiosis is a host-intrinsic regulator of tissue inflammation and tumor cell dissemination in hormone receptor-positive breast cancer

(2019) Claire Buchta Rosean et al.   CANCER RESEARCH

Age-Associated Changes in the Immune System and Blood–Brain Barrier Functions

(2019) Michelle Erickson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A comparison of single-cell trajectory inference methods

(2019) Wouter Saelens et al.   NATURE BIOTECHNOLOGY

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

Dual-Specificity Phosphatases in Immunity and Infection: An Update

(2019) Roland Lang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice

(2019) Karin Steinbach et al.   Science Translational Medicine

Single-cell transcriptomic profiling of the aging mouse brain

(2019) Methodios Ximerakis et al.   NATURE NEUROSCIENCE

Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

(2019) Hussein Al-Mossawi et al.   Nature Communications

The Central Nervous System Contains ILC1s That Differ From NK Cells in the Response to Inflammation

(2019) Silvina Romero-Suárez et al.   Frontiers in Immunology

Undulating changes in human plasma proteome profiles across the lifespan

(2019) Benoit Lehallier et al.   NATURE MEDICINE

A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain

(2018) Kristofer Davie et al.   CELL

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

(2018) Dunja Mrdjen et al.   IMMUNITY

Innate Lymphoid Cells: Diversity, Plasticity, and Unique Functions in Immunity

(2018) Marco Colonna   IMMUNITY

A Complex Proinflammatory Role for Peripheral Monocytes in Alzheimer's Disease

(2018) Marina Saresella et al.   JOURNAL OF ALZHEIMERS DISEASE

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C − Cells

(2017) Alexander Mildner et al.   IMMUNITY

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T memory stem cells in health and disease

(2017) Luca Gattinoni et al.   NATURE MEDICINE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

(2016) Meital Gury-BenAri et al.   CELL

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Communicating systems in the body: how microbiota and microglia cooperate

(2016) Daniel Erny et al.   IMMUNOLOGY

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

(2016) Timothy G. Dinan et al.   JOURNAL OF PHYSIOLOGY-LONDON

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

(2016) Cheryn J. Couter et al.   Jove-Journal of Visualized Experiments

Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair

(2015) Dietmar M.W. Zaiss et al.   IMMUNITY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Gut microbiota and aging

(2015) P. W. OToole et al.   SCIENCE

Ribosomal proteins: functions beyond the ribosome

(2015) Xiang Zhou et al.   Journal of Molecular Cell Biology

The dynamics of monocytes and microglia in Alzheimer’s disease

(2015) Peter Thériault et al.   Alzheimers Research & Therapy

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells

(2014) Xiao Z Shen et al.   LABORATORY INVESTIGATION

Characterization of T-Bet and Eomes in Peripheral Human Immune Cells

(2014) James J. Knox et al.   Frontiers in Immunology

Microbial shifts in the aging mouse gut

(2014) Morgan GI Langille et al.   Microbiome

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology