Incorporation of a Biocompatible Nanozyme in Cellular Antioxidant Enzyme Cascade Reverses Huntington's Like Disorder in Preclinical Model

Peroxidase‐Like Nanozymes Induce a Novel Form of Cell Death and Inhibit Tumor Growth In Vivo

(2020) Peixia Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Pro-Oxidant Therapeutic Activities of Cerium Oxide Nanoparticles in Colorectal Carcinoma Cells

(2020) Aparna Datta et al.   ACS Omega

Nanomaterials Exhibiting Enzyme-Like Properties (Nanozymes): Current Advances and Future Perspectives

(2019) Sanjay Singh   Frontiers in Chemistry

Impaired Redox Signaling in Huntington’s Disease: Therapeutic Implications

(2019) Bindu D. Paul et al.   Frontiers in Molecular Neuroscience

eg occupancy as an effective descriptor for the catalytic activity of perovskite oxide-based peroxidase mimics

(2019) Xiaoyu Wang et al.   Nature Communications

N- and B-Codoped Graphene: A Strong Candidate To Replace Natural Peroxidase in Sensitive and Selective Bioassays

(2019) Min Su Kim et al.   ACS Nano

Nanozymes: From New Concepts, Mechanisms, and Standards to Applications

(2019) Minmin Liang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Critical Comparison of the Superoxide Dismutase-like Activity of Carbon Antioxidant Nanozymes by Direct Superoxide Consumption Kinetic Measurements

(2019) Gang Wu et al.   ACS Nano

Heme Cofactor‐Resembling Fe–N Single Site Embedded Graphene as Nanozymes to Selectively Detect H 2 O 2 with High Sensitivity

(2019) Min Su Kim et al.   ADVANCED FUNCTIONAL MATERIALS

A Smart Nanotherapeutic Agent for in vitro and in vivo Reversal of Heavy‐Metal‐Induced Causality: Key Information from Optical Spectroscopy

(2019) Aniruddha Adhikari et al.   ChemMedChem

Site-selective photoinduced cleavage and profiling of DNA by chiral semiconductor nanoparticles

(2018) Maozhong Sun et al.   Nature Chemistry

Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes

(2018) Bing Jiang et al.   Nature Protocols

Emerging Biomedical Applications of Enzyme-Like Catalytic Nanomaterials

(2018) David P. Cormode et al.   TRENDS IN BIOTECHNOLOGY

Carbon Dot Nanozymes: How to Be Close to Natural Enzymes

(2018) Yang Lv et al.   CHEMISTRY-A EUROPEAN JOURNAL

Self-Assembly of Multi-nanozymes to Mimic an Intracellular Antioxidant Defense System

(2016) Yanyan Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparison of distribution and toxicity following repeated oral dosing of different vanadium oxide nanoparticles in mice

(2016) Eun-Jung Park et al.   ENVIRONMENTAL RESEARCH

Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers

(2016) Wei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The active site of low-temperature methane hydroxylation in iron-containing zeolites

(2016) Benjamin E. R. Snyder et al.   NATURE

Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

(2016) Richard Obexer et al.   Nature Chemistry

Visualizing Metal Content and Intracellular Distribution in Primary Hippocampal Neurons with Synchrotron X-Ray Fluorescence

(2016) Robert A. Colvin et al.   PLoS One

Targeting Oxidative Stress in Central Nervous System Disorders

(2016) Manisha Patel   TRENDS IN PHARMACOLOGICAL SCIENCES

Intrinsic superoxide dismutase activity of MnO nanoparticles enhances the magnetic resonance imaging contrast

(2016) R. Ragg et al.   Journal of Materials Chemistry B

Safe and symptomatic medicinal use of surface-functionalized Mn3O4 nanoparticles for hyperbilirubinemia treatment in mice

(2015) Nabarun Polley et al.   Nanomedicine

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease

(2014) Nan Wang et al.   NATURE MEDICINE

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

(2014) Amit A. Vernekar et al.   Nature Communications

Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms

(2014) Patrick Pla et al.   Frontiers in Behavioral Neuroscience

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

(2013) Hui Wei et al.   CHEMICAL SOCIETY REVIEWS

Rhes Deletion Is Neuroprotective in the 3-Nitropropionic Acid Model of Huntington's Disease

(2013) R. G. Mealer et al.   JOURNAL OF NEUROSCIENCE

Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

(2013) Robert P Mason et al.   NATURE GENETICS

The role of an oxometallic complex in OH dissociation during water oxidation: a microscopic insight from DFT study

(2013) Soumyajit Sarkar et al.   Journal of Materials Chemistry A

Nano-TiO2-Induced Apoptosis by Oxidative Stress-Mediated DNA Damage and Activation of p53 in Human Embryonic Kidney Cells

(2012) Ramovatar Meena et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation

(2012) Filipe Natalio et al.   Nature Nanotechnology

Cytotoxicity, oxidative stress, and genotoxicity in human hepatocyte and embryonic kidney cells exposed to ZnO nanoparticles

(2012) Rongfa Guan et al.   Nanoscale Research Letters

Antioxidants in Huntington's disease

(2011) Ashu Johri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Directed Evolution of a Protein Container

(2011) B. Worsdorfer et al.   SCIENCE

V2O5 Nanowires with an Intrinsic Peroxidase-Like Activity

(2010) Rute André et al.   ADVANCED FUNCTIONAL MATERIALS

SOD/catalase mimetic platinum nanoparticles inhibit heat-induced apoptosis in human lymphoma U937 and HH cells

(2010) Yoko Yoshihisa et al.   FREE RADICAL RESEARCH

Multi wall carbon nanotubes induce oxidative stress and cytotoxicity in human embryonic kidney (HEK293) cells

(2010) Anreddy Rama Narsimha Reddy et al.   TOXICOLOGY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Manganese Flux Across the Blood–Brain Barrier

(2009) Robert A. Yokel   NEUROMOLECULAR MEDICINE

Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells

(2009) Fen Wang et al.   TOXICOLOGY IN VITRO

Synthetic Biology for Synthetic Chemistry

(2008) Jay D. Keasling   ACS Chemical Biology

Prophylactic neuroprotective property of Centella asiatica against 3-nitropropionic acid induced oxidative stress and mitochondrial dysfunctions in brain regions of prepubertal mice

(2008) George K. Shinomol et al.   NEUROTOXICOLOGY