Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo
Authors
Keywords
-
Journal
Stem Cell Research & Therapy
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-14
DOI
10.1186/s13287-020-02050-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immune cell extracellular vesicles and their mitochondrial content decline with ageing
- (2020) Xin Zhang et al. Immunity & Ageing
- Rationale for the Use of Radiation-Activated Mesenchymal Stromal/Stem Cells in Acute Respiratory Distress Syndrome
- (2020) Isabel Tovar et al. Cells
- Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion
- (2019) Oliver D Yuan et al. STEM CELLS AND DEVELOPMENT
- Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
- (2019) Nádia de Cássia Noronha et al. Stem Cell Research & Therapy
- Concise Review: Mesenchymal Stromal Cell‐Derived Extracellular Vesicles for Regenerative Therapy and Immune Modulation: Progress and Challenges Toward Clinical Application
- (2019) David S. Allan et al. Stem Cells Translational Medicine
- MSC exosome works through a protein-based mechanism of action
- (2018) Wei Seong Toh et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- Altered Extracellular Vesicle Concentration, Cargo and Function in Diabetes Mellitus
- (2018) David W. Freeman et al. DIABETES
- Insights into inflammatory priming of mesenchymal stromal cells: functional biological impacts
- (2018) Mehdi Najar et al. INFLAMMATION RESEARCH
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6
- (2018) Sushma Chaubey et al. Stem Cell Research & Therapy
- Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning
- (2018) Joana R. Ferreira et al. Frontiers in Immunology
- Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli
- (2017) Margaret Alexander et al. JOURNAL OF IMMUNOLOGY
- Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis
- (2017) Yuxian Song et al. STEM CELLS
- Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
- (2017) J. Fafián-Labora et al. Scientific Reports
- A Proinflammatory Secretome Mediates the Impaired Immunopotency of Human Mesenchymal Stromal Cells in Elderly Patients with Atherosclerosis
- (2017) Özge Kizilay Mancini et al. Stem Cells Translational Medicine
- Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes
- (2017) Erez Eitan et al. Scientific Reports
- Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress
- (2016) Soshi Kanemoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration
- (2016) Vijay Bhaskar Reddy Konala et al. CYTOTHERAPY
- A20 plays a critical role in the immunoregulatory function of mesenchymal stem cells
- (2016) Rui-Jie Dang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury
- (2016) Manish Mittal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
- (2016) Joanna Kowal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling
- (2016) Johnathon D. Anderson et al. STEM CELLS
- Role of exosomes in the protection of cellular homeostasis
- (2016) Gabriela Desdín-Micó et al. Cell Adhesion & Migration
- Mechanisms of mesenchymal stem/stromal cell function
- (2016) Jeffrey L. Spees et al. Stem Cell Research & Therapy
- Inhibition of Myocardial Ischemia/Reperfusion Injury by Exosomes Secreted from Mesenchymal Stem Cells
- (2016) Heng Zhang et al. Stem Cells International
- Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions
- (2016) Mariano Di Trapani et al. Scientific Reports
- Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation
- (2015) Xiaomei Teng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b
- (2015) Dongdong Ti et al. Journal of Translational Medicine
- Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells
- (2015) Nahuel A. Garcia et al. PLoS One
- Extracellular Vesicles Secreted by Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stromal Cells Fail to Suppress Lymphocyte Proliferation
- (2015) Ana Valéria Gouveia de Andrade et al. STEM CELLS AND DEVELOPMENT
- Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy
- (2015) Chun-yu Li et al. Stem Cell Research & Therapy
- Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
- (2015) Ozge Kizilay Mancini et al. Stem Cell Research & Therapy
- Exosome Secretion by the Parasitic Protozoan Leishmania within the Sand Fly Midgut
- (2015) Vanessa Diniz Atayde et al. Cell Reports
- Comparing the Immunomodulatory Properties of Bone Marrow, Adipose Tissue, and Birth-Associated Tissue Mesenchymal Stromal Cells
- (2015) Philipp Mattar et al. Frontiers in Immunology
- Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells
- (2014) Tae Hoon Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TSG-6 Inhibits Neutrophil Migration via Direct Interaction with the Chemokine CXCL8
- (2014) D. P. Dyer et al. JOURNAL OF IMMUNOLOGY
- Paracrine Effect of Mesenchymal Stem Cells Derived from Human Adipose Tissue in Bone Regeneration
- (2014) Itali Linero et al. PLoS One
- A Systematic Review of Preclinical Studies on the Therapeutic Potential of Mesenchymal Stromal Cell-Derived Microvesicles
- (2014) Celine Akyurekli et al. Stem Cell Reviews and Reports
- Microvescicles Derived from Mesenchymal Stromal Cells Are Not as Effective as Their Cellular Counterpart in the Ability to Modulate Immune Responses In Vitro
- (2014) Antonella Conforti et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
- (2014) Cheau Tan et al. Stem Cell Research & Therapy
- Prospect of Stem Cell Conditioned Medium in Regenerative Medicine
- (2014) Jeanne Adiwinata Pawitan Biomed Research International
- Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells
- (2014) Rebeca Blazquez et al. Frontiers in Immunology
- Immunological characterization of multipotent mesenchymal stromal cells—The International Society for Cellular Therapy (ISCT) working proposal
- (2013) Mauro Krampera et al. CYTOTHERAPY
- TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity
- (2013) D. J. Kota et al. DIABETES
- A20 in inflammation and autoimmunity
- (2013) Leen Catrysse et al. TRENDS IN IMMUNOLOGY
- Adipose Tissue-Derived Multipotent Stromal Cells Have a Higher Immunomodulatory Capacity Than Their Bone Marrow-Derived Counterparts
- (2013) Sara M. Melief et al. Stem Cells Translational Medicine
- Microvesicles derived from mesenchymal stem cells: Potent organelles for induction of tolerogenic signaling
- (2012) Aram Mokarizadeh et al. IMMUNOLOGY LETTERS
- Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life
- (2012) Brooke L. Deatherage et al. INFECTION AND IMMUNITY
- Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation
- (2012) L. von Bahr et al. STEM CELLS
- Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
- (2011) Rebecca A. Dragovic et al. Nanomedicine-Nanotechnology Biology and Medicine
- Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction
- (2011) Leo Timmers et al. Stem Cell Research
- Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses
- (2011) Angélique Bobrie et al. TRAFFIC
- Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling
- (2010) Arthit Chairoungdua et al. JOURNAL OF CELL BIOLOGY
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6
- (2009) Ryang Hwa Lee et al. Cell Stem Cell
- Rab27a and Rab27b control different steps of the exosome secretion pathway
- (2009) Matias Ostrowski et al. NATURE CELL BIOLOGY
- Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
- (2008) Johan Skog et al. NATURE CELL BIOLOGY
- Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
- (2008) Robert R Graham et al. NATURE GENETICS
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
- Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
- (2008) Leo Timmers et al. Stem Cell Research
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started