Addressing the challenges of E-cigarette safety profiling by assessment of pulmonary toxicological response in bronchial and alveolar mucosa models

A Summary of In Vitro and In Vivo Studies Evaluating the Impact of E-Cigarette Exposure on Living Organisms and the Environment

(2020) Anna Merecz-Sadowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Determining the impact of flavored e-liquids on aldehyde production during Vaping

(2020) I. Gene Gillman et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Identification of Cytotoxic Flavor Chemicals in Top-Selling Electronic Cigarette Refill Fluids

(2019) My Hua et al.   Scientific Reports

Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data

(2019) Koustav Ganguly et al.   CRITICAL REVIEWS IN TOXICOLOGY

Toxicity assessment of electronic cigarettes

(2019) Guanghe Wang et al.   INHALATION TOXICOLOGY

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

(2019) Matthew C. Madison et al.   JOURNAL OF CLINICAL INVESTIGATION

Exposure of normal and chronic bronchitis-like mucosa models to aerosolized carbon nanoparticles: comparison of pro-inflammatory oxidative stress and tissue injury/repair responses

(2019) Jie Ji et al.   Nanotoxicology

Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Preliminary Report

(2019) Jennifer E. Layden et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaping-induced Acute Lung Injury: An Epidemic That Could Have Been Prevented

(2019) John R. Balmes   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Use of social media to establish vapers puffing behaviour: Findings and implications for laboratory evaluation of e-cigarette emissions

(2019) Kevin McAdam et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Flavored Tobacco Product Use Among Middle and High School Students — United States, 2014–2018

(2019) Karen A. Cullen et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Evaluation of diacetyl mediated pulmonary effects in physiologically relevant air-liquid interface models of human primary bronchial epithelial cells

(2019) Tania A. Thimraj et al.   TOXICOLOGY IN VITRO

Effects of E-Cigarette Use on Human Lung Tissue. On Harm Reduction and Causing Harm

(2018) Pieter S. Hiemstra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Electronic cigarette use in youths: a position statement of the Forum of International Respiratory Societies

(2018) Thomas W. Ferkol et al.   EUROPEAN RESPIRATORY JOURNAL

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

(2018) Jie Ji et al.   Particle and Fibre Toxicology

Inflammatory effects of acrolein, crotonaldehyde and hexanal vapors on human primary bronchial epithelial cells cultured at air-liquid interface

(2018) Aishwarya M. Dwivedi et al.   TOXICOLOGY IN VITRO

Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products

(2018) Gurjot Kaur et al.   TOXICOLOGY LETTERS

The Chemical and Products Database, a resource for exposure-relevant data on chemicals in consumer products

(2018) Kathie L. Dionisio et al.   Scientific Data

Evaluation of E-Vapor Nicotine and Nicotyrine Concentrations under Various E-Liquid Compositions, Device Settings, and Vaping Topographies

(2018) Yeongkwon Son et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Patterns, trends and determinants of e-cigarette use in 28 European Union Member States 2014–2017

(2018) Anthony A. Laverty et al.   PREVENTIVE MEDICINE

Electronic Cigarettes – Task Force report from the European Respiratory Society

(2018) Robert Bals et al.   EUROPEAN RESPIRATORY JOURNAL

Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts

(2017) Jennifer M. Logue et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Multicomponent aerosol particle deposition in a realistic cast of the human upper respiratory tract

(2017) Markus Nordlund et al.   INHALATION TOXICOLOGY

Aerodynamic particle size distribution and dynamic properties in aerosols from electronic cigarettes

(2017) Mikael Sundahl et al.   JOURNAL OF AEROSOL SCIENCE

The Prevalence and Characteristics of E-Cigarette Users in the U.S.

(2017) et al.   International Journal of Environmental Research and Public Health

Benzene formation in electronic cigarettes

(2017) James F. Pankow et al.   PLoS One

Comparison of Puff Volume With Cigarettes per Day in Predicting Nicotine Uptake Among Daily Smokers

(2016) Nicolle M. Krebs et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Nicotinic acetylcholine receptor expression in human airway correlates with lung function

(2016) David Chi-Leung Lam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chemical Composition of Aerosol from an E-Cigarette: A Quantitative Comparison with Cigarette Smoke

(2016) Jennifer Margham et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Secretory leukocyte protease inhibitor (SLPI), a multifunctional protein in the host defense response

(2016) Monika Majchrzak-Gorecka et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Emissions from Electronic Cigarettes: Key Parameters Affecting the Release of Harmful Chemicals

(2016) Mohamad Sleiman et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effect of variable power levels on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols

(2016) I.G. Gillman et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Tobacco Use Among Middle and High School Students — United States, 2011–2015

(2016) Tushar Singh et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants

(2015) Megan Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Causation of Cigarette Smoke–Induced Emphysema by p-Benzoquinone and Its Prevention by Vitamin C

(2015) Arunava Ghosh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes

(2015) Joseph G. Allen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Particle doses in the pulmonary lobes of electronic and conventional cigarette users

(2015) Maurizio Manigrasso et al.   ENVIRONMENTAL POLLUTION

Characterisation of mainstream and passive vapours emitted by selected electronic cigarettes

(2015) Otmar Geiss et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation

(2015) Carlos A. Báez-Pagán et al.   Journal of Neuroimmune Pharmacology

Electronic cigarettes: The nicotyrine hypothesis

(2015) Aaron Abramovitz et al.   MEDICAL HYPOTHESES

Cytotoxic Evaluation of e-Liquid Aerosol using Different Lung-Derived Cell Models

(2015) Stefanie Scheffler et al.   International Journal of Environmental Research and Public Health

Abnormalities in Airway Epithelial Junction Formation in Chronic Obstructive Pulmonary Disease

(2014) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Peering through the mist: systematic review of what the chemistry of contaminants in electronic cigarettes tells us about health risks

(2014) Igor Burstyn   BMC PUBLIC HEALTH

Electronic Cigarette Liquid Increases Inflammation and Virus Infection in Primary Human Airway Epithelial Cells

(2014) Qun Wu et al.   PLoS One

Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling

(2013) Ming-Sheng Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Influential parameters on particle concentration and size distribution in the mainstream of e-cigarettes

(2013) F.C. Fuoco et al.   ENVIRONMENTAL POLLUTION

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

(2013) Maarten van den Berge et al.   THORAX

Review article: ulcerative colitis, smoking and nicotine therapy

(2012) P. C. Lunney et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Electronic cigarette aerosol particle size distribution measurements

(2012) Bradley J. Ingebrethsen et al.   INHALATION TOXICOLOGY

Comparison of the effects of e-cigarette vapor and cigarette smoke on indoor air quality

(2012) T. R. McAuley et al.   INHALATION TOXICOLOGY

Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery

(2011) I. H. Heijink et al.   EUROPEAN RESPIRATORY JOURNAL

1,4-Benzoquinone (PBQ) Induced Toxicity in Lung Epithelial Cells Is Mediated by the Disruption of the Microtubule Network and Activation of Caspase-3

(2010) Amlan Das et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

(2010) Maria Tsoumakidou et al.   EXPERIMENTAL LUNG RESEARCH

Budesonide enhances Toll-like receptor 2 expression in activated bronchial epithelial cells

(2010) Ida von Scheele et al.   INHALATION TOXICOLOGY

Nicotine suppresses inflammatory factors in HBE16 airway epithelial cells after exposure to cigarette smoke extract and lipopolysaccharide

(2010) Qi Li et al.   Translational Research

Nicotine and inflammatory neurological disorders

(2009) Wen-Hua Piao et al.   ACTA PHARMACOLOGICA SINICA

Effect of Budesonide and Formoterol on Il-6 and Il-8 Release from Primary Bronchial Epithelial Cells

(2008) Karin Strandberg et al.   JOURNAL OF ASTHMA

Mechanism and Tissue Specificity of Nicotine-mediated LungS-Adenosylmethionine Reduction

(2008) Camilo A. Moncada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY